CD4 Antibody | R&D Systems MAB554-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

CD4 Antibody

catalog :

MAB554-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

479 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

GK1.5

reactivity :

mouse

application :

immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 6f	Liang Z, He P, Han Y, Yun C. Survival of Stem Cells and Progenitors in the Intestine Is Regulated by LPA5-Dependent Signaling. Cell Mol Gastroenterol Hepatol. 2022;14:129-150 pubmed publisher
	Balakrishnan B, Luckey D, Wright K, Davis J, Chen J, Taneja V. Eggerthella lenta augments preclinical autoantibody production and metabolic shift mimicking senescence in arthritis. Sci Adv. 2023;9:eadg1129 pubmed publisher
	Shi S, Xiu Y, Li Y, Yuan M, Shi K, Liu Q, et al. CD4+ T cells aggravate hemorrhagic brain injury. Sci Adv. 2023;9:eabq0712 pubmed publisher
	Lee J, Ostalecki C, Oberstein T, Schierer S, Zinser E, Eberhardt M, et al. Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus. EBioMedicine. 2022;77:103903 pubmed publisher
	Halder S, Milner R. Chronic mild hypoxia accelerates recovery from preexisting EAE by enhancing vascular integrity and apoptosis of infiltrated monocytes. Proc Natl Acad Sci U S A. 2020;117:11126-11135 pubmed publisher
	Huang Y, Hu H, Liu L, Ye J, Wang Z, Que B, et al. Interleukin-12p35 Deficiency Reverses the Th1/Th2 Imbalance, Aggravates the Th17/Treg Imbalance, and Ameliorates Atherosclerosis in ApoE-/- Mice. Mediators Inflamm. 2019;2019:3152040 pubmed publisher
	Halder S, Kant R, Milner R. Hypoxic pre-conditioning suppresses experimental autoimmune encephalomyelitis by modifying multiple properties of blood vessels. Acta Neuropathol Commun. 2018;6:86 pubmed publisher
	Wiehagen K, Girgis N, Yamada D, Smith A, Chan S, Grewal I, et al. Combination of CD40 Agonism and CSF-1R Blockade Reconditions Tumor-Associated Macrophages and Drives Potent Antitumor Immunity. Cancer Immunol Res. 2017;5:1109-1121 pubmed publisher
	Tanaka R, Goshima F, Esaki S, Sato Y, Murata T, Nishiyama Y, et al. The efficacy of combination therapy with oncolytic herpes simplex virus HF10 and dacarbazine in a mouse melanoma model. Am J Cancer Res. 2017;7:1693-1703 pubmed
	Aloisio G, Nakada Y, Saatcioglu H, Peña C, Baker M, Tarnawa E, et al. PAX7 expression defines germline stem cells in the adult testis. J Clin Invest. 2014;124:3929-44 pubmed publisher
	Goshima F, Esaki S, Luo C, Kamakura M, Kimura H, Nishiyama Y. Oncolytic viral therapy with a combination of HF10, a herpes simplex virus type 1 variant and granulocyte-macrophage colony-stimulating factor for murine ovarian cancer. Int J Cancer. 2014;134:2865-77 pubmed publisher
	Mills J, Alabanza L, Mahamed D, Bynoe M. Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitis. J Neuroinflammation. 2012;9:193 pubmed
	Hokeness K, Deweerd E, Munks M, Lewis C, Gladue R, Salazar Mather T. CXCR3-dependent recruitment of antigen-specific T lymphocytes to the liver during murine cytomegalovirus infection. J Virol. 2007;81:1241-50 pubmed
	Dajee M, Muchamuel T, Schryver B, Oo A, Alleman Sposeto J, De Vry C, et al. Blockade of experimental atopic dermatitis via topical NF-kappaB decoy oligonucleotide. J Invest Dermatol. 2006;126:1792-803 pubmed

image

image 1 :

CD4 antibody in Mouse Intestine by Immunohistochemistry (IHC-Fr).

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB554

SKU :

MAB554-100

product name :

CD4 Antibody

Description :

The Mouse CD4 Antibody from R&D Systems is a rat monoclonal antibody to CD4. This antibody reacts with mouse. The Mouse CD4 Antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Cell depletion, Costimulation of T Cells, Inhibition of T Cell Function, CyTOF-ready.

target :

CD4

category :

Primary Antibodies

unit size :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

GK1.5

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse CTL clone V4

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Reacts with mouse CD4, an antigen co-receptor on the T cell surface which interacts with MHC II molecules on antigen presenting cells.

gene symbol :

CD4

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

applications :

Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Cell depletion, Costimulation of T Cells, Inhibition of T Cell Function, CyTOF-ready

USD :

479 USD

alt names :

CD_antigen: CD4, CD4, CD4 antigen, CD4 antigen (p55), CD4 molecule, CD4 receptor, CD4mut, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage