CCR2 Antibody | R&D Systems MAB55381-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

CCR2 Antibody

catalog :

MAB55381-100

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

475301

reactivity :

mouse

application :

flow cytometry, mass cytometry

more info or order :

R&D Systems product webpage

citations: 19

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig s3c	Petermann M, Orfanos Z, Sellau J, Gharaibeh M, Lotter H, Fleischer B, et al. CCR2 Deficiency Impairs Ly6Clo and Ly6Chi Monocyte Responses in Orientia tsutsugamushi Infection. Front Immunol. 2021;12:670219 pubmed publisher
mass cytometry; mouse; loading ...; fig s3	Lagnado A, Leslie J, Ruchaud Sparagano M, Victorelli S, Hirsova P, Ogrodnik M, et al. Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner. EMBO J. 2021;40:e106048 pubmed publisher
	Fulton S, Bendl J, Gameiro Ros I, Fullard J, Al Kachak A, Lepack A, et al. ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex. bioRxiv. 2023;: pubmed publisher
	Kurtz S, De Pascalis R, Meierovics A, Elkins K. Deficiency in CCR2 increases susceptibility of mice to infection with an intracellular pathogen, Francisella tularensis LVS, but does not impair development of protective immunity. PLoS ONE. 2021;16:e0249142 pubmed publisher
	Xu J, Wang J, Wang X, Tan R, Qi X, Liu Z, et al. Soluble PD-L1 improved direct ARDS by reducing monocyte-derived macrophages. Cell Death Dis. 2020;11:934 pubmed publisher
	Regan D, Coy J, Chahal K, Chow L, Kurihara J, Guth A, et al. The Angiotensin Receptor Blocker Losartan Suppresses Growth of Pulmonary Metastases via AT1R-Independent Inhibition of CCR2 Signaling and Monocyte Recruitment. J Immunol. 2019;202:3087-3102 pubmed publisher
	Yang W, Zhao X, Tao Y, Wu Y, He F, Tang L. Proteomic analysis reveals a protective role of specific macrophage subsets in liver repair. Sci Rep. 2019;9:2953 pubmed publisher
	Dick S, Macklin J, Nejat S, Momen A, Clemente Casares X, Althagafi M, et al. Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction. Nat Immunol. 2019;20:29-39 pubmed publisher
	Zhan Y, Wang N, Vasanthakumar A, Zhang Y, Chopin M, Nutt S, et al. CCR2 enhances CD25 expression by FoxP3+ regulatory T cells and regulates their abundance independently of chemotaxis and CCR2+ myeloid cells. Cell Mol Immunol. 2018;: pubmed publisher
	Wang J, Seo M, Deci M, Weil B, Canty J, Nguyen J. Effect of CCR2 inhibitor-loaded lipid micelles on inflammatory cell migration and cardiac function after myocardial infarction. Int J Nanomedicine. 2018;13:6441-6451 pubmed
	Wu J, Zhang R, Hu G, Zhu H, Gao W, Xue J. Carbon Monoxide Impairs CD11b+Ly-6Chi Monocyte Migration from the Blood to Inflamed Pancreas via Inhibition of the CCL2/CCR2 Axis. J Immunol. 2018;200:2104-2114 pubmed publisher
	Perry C, Muñoz Rojas A, Meeth K, Kellman L, Amezquita R, Thakral D, et al. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. J Exp Med. 2018;215:877-893 pubmed publisher
	Mao K, Baptista A, Tamoutounour S, Zhuang L, Bouladoux N, Martins A, et al. Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism. Nature. 2018;554:255-259 pubmed publisher
	Takeda K, WEBB T, Ning F, Shiraishi Y, Regan D, Chow L, et al. Mesenchymal Stem Cells Recruit CCR2+ Monocytes To Suppress Allergic Airway Inflammation. J Immunol. 2018;200:1261-1269 pubmed publisher
	Wu X, Dayanand K, Thylur R, Norbury C, Gowda D. Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes. J Biol Chem. 2017;292:13615-13634 pubmed publisher
	Putz E, Mayfosh A, Kos K, Barkauskas D, Nakamura K, Town L, et al. NK cell heparanase controls tumor invasion and immune surveillance. J Clin Invest. 2017;127:2777-2788 pubmed publisher
	Sagar D, Singh N, Ginwala R, Huang X, Philip R, Nagarkatti M, et al. Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity. Sci Rep. 2017;7:2707 pubmed publisher
	Chatziandreou N, Farsakoglu Y, Palomino Segura M, D Antuono R, Pizzagalli D, Sallusto F, et al. Macrophage Death following Influenza Vaccination Initiates the Inflammatory Response that Promotes Dendritic Cell Function in the Draining Lymph Node. Cell Rep. 2017;18:2427-2440 pubmed publisher
	Meierovics A, Cowley S. MAIT cells promote inflammatory monocyte differentiation into dendritic cells during pulmonary intracellular infection. J Exp Med. 2016;213:2793-2809 pubmed

image

image 1 :

Detection of CCR2 antibody in NS0 Mouse Cell Line Transfected with Mouse CCR2 and eGFP antibody by Flow Cytometry.

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB55381

SKU :

MAB55381-100

product name :

CCR2 Antibody

Description :

The Mouse CCR2 Antibody from R&D Systems is a rat monoclonal antibody to CCR2. This antibody reacts with mouse. The Mouse CCR2 Antibody has been validated for the following applications: Flow Cytometry.

target :

CCR2

category :

Primary Antibodies

unit size :

100 ug (also 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

475301

conjugate :

Unconjugated

host :

Rat

immunogen :

L1.2 mouse pro-B cell line transfected with mouse CCR2

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse CCR2 transfectants but not the parental cell line in flow cytometry. Does not detect HEK293 human embryonic kidney cell line transfected with mouse CCR5 in flow cytometry.

applications :

Flow Cytometry

USD :

479 USD

alt names :

C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CC-CKR-2CKR2B, CCR2, CCR-2, CCR2A, CCR2B, CD192, CD192 antigen, chemokine (C-C motif) receptor 2, CKR2, CKR2A, CMKBR2, CMKBR2MGC111760, FLJ78302, MCP-1 receptor, MCP-1-R, MCP-1-RMGC103828, MGC168006, Monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage