Klotho Antibody | R&D Systems MAB5334-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Klotho Antibody

catalog :

MAB5334-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

479 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

775340

reactivity :

human

application :

neutralization

more info or order :

R&D Systems product webpage

citations: 2

Reference
Suk Kang J, Son S, Lee J, Lee S, Jeong A, Lee E, et al. Protective effects of klotho on palmitate-induced podocyte injury in diabetic nephropathy. PLoS ONE. 2021;16:e0250666 pubmed publisher
Zhong X, Jagarlapudi S, Weng Y, Ly M, Rouse J, McClure K, et al. Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease. J Biol Chem. 2020;295:3115-3133 pubmed publisher

image

image 1 :

Cell Proliferation Induced by Klotho and Neutralization by Human Klotho Antibody.

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB5334

SKU :

MAB5334-100

product name :

Klotho Antibody

Description :

The Human Klotho Antibody from R&D Systems is a rat monoclonal antibody to Klotho. This antibody reacts with human. The Human Klotho Antibody has been validated for the following applications: Neutralization.

target :

Klotho

category :

Primary Antibodies

unit size :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

775340

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Klotho, Glu34-Ser981, Accession # Q9UEF7

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Klotho in direct ELISAs. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse (rm) Klotho (aa 35-982) is observed and no cross-reactivity with rmKlotho (aa 23-550), recombinant human (rh) Klotho beta (aa 53-997), or rhCytosolic beta-Glucosidase/GBA3 is observed.

gene symbol :

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

Q9UEF7

applications :

Neutralization

USD :

479 USD

alt names :

EC 3.2.1, EC 3.2.1.31, KL, klotho

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage