uPAR Antibody | R&D Systems MAB531-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

uPAR Antibody

catalog :

MAB531-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

469 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

109801

reactivity :

mouse

application :

western blot, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Cheng Y, Hall T, Xu X, Yung I, Souza D, Zheng J, et al. Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease. EBioMedicine. 2022;75:103758 pubmed publisher
Amor C, Feucht J, Leibold J, Ho Y, Zhu C, Alonso Curbelo D, et al. Senolytic CAR T cells reverse senescence-associated pathologies. Nature. 2020;583:127-132 pubmed publisher
Yang X, Lin Y, Shi Y, Li B, Liu W, Yin W, et al. FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling. Cancer Res. 2016;76:4124-35 pubmed publisher
Endo Munoz L, Cai N, Cumming A, Macklin R, Merida de Long L, Topkas E, et al. Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis. PLoS ONE. 2015;10:e0133592 pubmed publisher
Narayanaswamy P, Hodjat M, Haller H, Dumler I, Kiyan Y. Loss of urokinase receptor sensitizes cells to DNA damage and delays DNA repair. PLoS ONE. 2014;9:e101529 pubmed publisher
Nagai N, Okada K, Kawao N, Ishida C, Ueshima S, Collen D, et al. Urokinase-type plasminogen activator receptor (uPAR) augments brain damage in a murine model of ischemic stroke. Neurosci Lett. 2008;432:46-9 pubmed publisher

image

image 1 :

Detection of uPAR antibody in Mouse Blood Monocytes antibody by Flow Cytometry.

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB531

SKU :

MAB531-100

product name :

uPAR Antibody

Description :

The Mouse uPAR Antibody from R&D Systems is a rat monoclonal antibody to uPAR. This antibody reacts with mouse. The Mouse uPAR Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Blockade of Receptor-ligand Interaction, CyTOF-reported.

target :

uPAR

category :

Primary Antibodies

unit size :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

109801

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse uPAR isoform 1, Leu24-Thr297, Accession # P35456

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse uPAR in Western blots. In Western blots, no cross-reactivity with recombinant human uPAR is observed.

gene symbol :

PLAUR

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

P35456

applications :

Western Blot, Flow Cytometry, Blockade of Receptor-ligand Interaction, CyTOF-reported

USD :

469 USD

alt names :

CD87, CD87 antigen, Monocyte activation antigen Mo3, plasminogen activator, urokinase receptor, PLAUR, uPAR, U-PAR, UPARurokinase plasminogen activator surface receptor, u-plasminogen activator receptor form 2, URKRMO3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage