product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Mouse CCL24/Eotaxin-2/MPIF-2 Antibody
catalog :
MAB528-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
449 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
106521
reactivity :
human, mouse
application :
western blot, ELISA, neutralization
more info or order :
R&D Systems product webpage
citations: 8
Reference
Mittelsteadt K, Hayes E, Campbell D. ICOS signaling limits regulatory T cell accumulation and function in visceral adipose tissue. J Exp Med. 2021;218: pubmed publisher
Ventura S, Cano F, Kannan Y, Breyer F, Pattison M, Wilson M, et al. A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation. J Exp Med. 2018;215:2737-2747 pubmed publisher
Kannan Y, Entwistle L, Pelly V, Perez Lloret J, Walker A, Ley S, et al. TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus. PLoS Pathog. 2017;13:e1006536 pubmed publisher
Byrne A, Weiss M, Mathie S, Walker S, Eames H, Saliba D, et al. A critical role for IRF5 in regulating allergic airway inflammation. Mucosal Immunol. 2017;10:716-726 pubmed publisher
Denney L, Byrne A, Shea T, Buckley J, Pease J, Herledan G, et al. Pulmonary Epithelial Cell-Derived Cytokine TGF-β1 Is a Critical Cofactor for Enhanced Innate Lymphoid Cell Function. Immunity. 2015;43:945-58 pubmed publisher
Dai C, Yao X, Gordon E, Barochia A, Cuento R, Kaler M, et al. A CCL24-dependent pathway augments eosinophilic airway inflammation in house dust mite-challenged Cd163(-/-) mice. Mucosal Immunol. 2016;9:702-17 pubmed publisher
Wakashin H, Hirose K, Maezawa Y, Kagami S, Suto A, Watanabe N, et al. IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice. Am J Respir Crit Care Med. 2008;178:1023-32 pubmed publisher
Shibamori M, Ogino K, Kambayashi Y, Ishiyama H. Intranasal mite allergen induces allergic asthma-like responses in NC/Nga mice. Life Sci. 2006;78:987-94 pubmed
product information
master code :
MAB528
SKU :
MAB528-100
product name :
Mouse CCL24/Eotaxin-2/MPIF-2 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Mouse CCL24/Eotaxin-2/MPIF-2 Antibody from R&D Systems is a rat monoclonal antibody to CCL24/Eotaxin-2/MPIF-2. This antibody reacts with mouse. The Mouse CCL24/Eotaxin-2/MPIF-2 Antibody has been validated for the following applications: ELISA Development,ELISA Development (Capture),Neutralization,Western Blot,ELISA Capture (Matched Antibody Pair).
target :
CCL24/Eotaxin-2/MPIF-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
106521
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse CCL24/Eotaxin-2/MPIF-2, Ile24-Val119, Accession # Q9JKC0
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CCL24/Eotaxin-2/MPIF-2 in Western blots. In Western blots, no cross-reactivity with recombinant human CCL1, 2, 3, 4, 5, 7, 8, 11, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 28, recombinant mouse CCL1, 2, 3, 4, 6, 7, 9/10/MIP-1 gamma , 11, 12, 19, 20, 21, 22, 25, 28, or recombinant rat CCL20 is observed.
gene symbol :
CCL24
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Chemotaxis Induced by CCL24/Eotaxin-2 and Neutral-ization by Mouse CCL24/ Eotaxin-2 Antibody.
accessionNumbers :
Q9JKC0
applications :
ELISA Development,ELISA Development (Capture),Neutralization,Western Blot,ELISA Capture (Matched Antibody Pair)
USD :
449 USD
alt names :
chemokine (C-C motif) ligand 24, Ckb-6, Eosinophil chemotactic protein 2, Eotaxin-2, member 24, MPIF2, MPIF-2, MPIF2Myeloid progenitor inhibitory factor 2, MPIF-2Small-inducible cytokine A24, SCYA24CK-beta-6
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.