Mouse Fas Ligand/TNFSF6 Antibody | R&D Systems MAB5262 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Fas Ligand/TNFSF6 Antibody

catalog :

MAB5262

quantity :

500 ug (also 25 ug)

price :

559 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

101626

reactivity :

mouse

application :

western blot, ELISA, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 7

Reference
Dumitrescu M, Trusca V, Savu L, Stancu I, Ratiu A, Simionescu M, et al. Adenovirus-Mediated FasL Minigene Transfer Endows Transduced Cells with Killer Potential. Int J Mol Sci. 2020;21: pubmed publisher
Svandová E, Veselá B, Lesot H, Sadoine J, Poliard A, Matalova E. FasL Modulates Expression of Mmp2 in Osteoblasts. Front Physiol. 2018;9:1314 pubmed publisher
Secinaro M, Fortner K, Dienz O, Logan A, Murphy M, Anathy V, et al. Glycolysis promotes caspase-3 activation in lipid rafts in T cells. Cell Death Dis. 2018;9:62 pubmed publisher
Fortner K, Bond J, Austin J, Boss J, Budd R. The molecular signature of murine T cell homeostatic proliferation reveals both inflammatory and immune inhibition patterns. J Autoimmun. 2017;82:47-61 pubmed publisher
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed publisher
Wildbaum G, Zohar Y, Karin N. Antigen-specific CD25- Foxp3- IFN-gamma(high) CD4+ T cells restrain the development of experimental allergic encephalomyelitis by suppressing Th17. Am J Pathol. 2010;176:2764-75 pubmed publisher
Krum S, Miranda Carboni G, Hauschka P, Carroll J, Lane T, Freedman L, et al. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. EMBO J. 2008;27:535-45 pubmed publisher

product information

master code :

MAB5262

SKU :

MAB5262

product name :

Mouse Fas Ligand/TNFSF6 Antibody

unit size :

500 ug (also 25 ug)

description :

The Mouse Fas Ligand/TNFSF6 Antibody from R&D Systems is a rat monoclonal antibody to Fas Ligand/TNFSF6. This antibody reacts with mouse. The Mouse Fas Ligand/TNFSF6 Antibody has been validated for the following applications: Inhibition,Luminex Development,Western Blot,Neutralization,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair).

target :

Fas Ligand/TNFSF6

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

101626

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Fas Ligand/TNFSF6, Pro132-Leu279, Accession # P41047

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse Fas Ligand/TNFSF6 in ELISAs and Western blots. In Western blots, approximately 2% cross-reactivity with recombinant mouse (rm) TNF-alpha is observed and no cross-reactivity with recombinant human (rh) APRIL, rhFas Ligand, rhGITR Ligand, rhLIGHT, rhTRAIL, rmTRANCE, and rhVEGI is observed.

gene symbol :

Fasl

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cytotoxicity Induced by Fas Ligand/TNFSF6 and Neutralization by Mouse Fas Ligand/TNFSF6 Antibody.

accessionNumbers :

P41047

applications :

Inhibition,Luminex Development,Western Blot,Neutralization,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair)

USD :

559 USD

alt names :

apoptosis (APO-1) antigen ligand 1, Apoptosis antigen ligand, APT1LG1CD95L, APTL, CD178, CD178 antigen, CD95L, CD95-L, Fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, member 6), FASLCD95 ligand, FASLG, TNFSF6, TNFSF6FasL, tumor necrosis factor (ligand) superfamily, member 6, tumor necrosis factor ligand superfamily member 6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage