product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse GITR/TNFRSF18 Antibody
catalog :
MAB5241
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
108619
reactivity :
mouse
application :
western blot, flow cytometry
more info or order :
R&D Systems product webpage
citations: 4
Reference
Dobrzynski E, Fitzgerald J, Cao O, Mingozzi F, Wang L, Herzog R. Prevention of cytotoxic T lymphocyte responses to factor IX-expressing hepatocytes by gene transfer-induced regulatory T cells. Proc Natl Acad Sci U S A. 2006;103:4592-7 pubmed
Huang X, Zhu J, Yang Y. Protection against autoimmunity in nonlymphopenic hosts by CD4+ CD25+ regulatory T cells is antigen-specific and requires IL-10 and TGF-beta. J Immunol. 2005;175:4283-91 pubmed
Ji H, Liao G, Faubion W, Abadia Molina A, Cozzo C, Laroux F, et al. Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression. J Immunol. 2004;172:5823-7 pubmed
Khattri R, Cox T, Yasayko S, Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol. 2003;4:337-42 pubmed
product information
master code :
MAB5241
SKU :
MAB5241
product name :
Mouse GITR/TNFRSF18 Antibody
unit size :
500 ug (also 25 ug)
description :
The Mouse GITR/TNFRSF18 Antibody from R&D Systems is a rat monoclonal antibody to GITR/TNFRSF18. This antibody reacts with mouse. The Mouse GITR/TNFRSF18 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,CyTOF-ready.
target :
GITR/TNFRSF18
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
108619
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse GITR/TNFRSF18, Met1-His153, Accession # O35714
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse GITR/TNFRSF18 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) 4-1BB, recombinant mouse (rm) CD27, rmCD30, rmEDAR, rmFas, rhGITR, rhHVEM, rmRANK, rhTROY, and rmTNF R1 is observed.
gene symbol :
TNFRSF18
accessionNumbers :
O35714
applications :
Flow Cytometry,Western Blot,CyTOF-ready
USD :
559 USD
alt names :
Activation-inducible TNFR family receptor, AITR, AITRTNF receptor superfamily activation-inducible protein, CD357, CD357 antigen, GITR-D, GITRtumor necrosis factor receptor superfamily member 18, Glucocorticoid-induced TNFR-related protein, TNFRSF18, tumor necrosis factor receptor superfamily, member 18
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.