ST2/IL-33R Antibody | R&D Systems MAB523-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

ST2/IL-33R Antibody

catalog :

MAB523-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

448 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

97203

reactivity :

human

application :

western blot, ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 8

Reference
Camiolo M, Zhou X, Oriss T, Yan Q, Gorry M, Horne W, et al. High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status. Cell Rep. 2021;35:108974 pubmed publisher
Ramadan A, Daguindau E, Rech J, Chinnaswamy K, Zhang J, Hura G, et al. From proteomics to discovery of first-in-class ST2 inhibitors active in vivo. JCI Insight. 2018;3: pubmed publisher
Wu C, Wu Y, Cheng C, Hong Z, Shi Z, Lin S, et al. Interleukin-33 Predicts Poor Prognosis and Promotes Renal Cell Carcinoma Cell Growth Through its Receptor ST2 and the JNK Signaling Pathway. Cell Physiol Biochem. 2018;47:191-200 pubmed publisher
Díaz Jiménez D, Núñez L, De la Fuente M, Dubois Camacho K, Sepulveda H, Montecino M, et al. A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis. Sci Rep. 2017;7:10180 pubmed publisher
Blom L, Poulsen L. IL-1 family members IL-18 and IL-33 upregulate the inflammatory potential of differentiated human Th1 and Th2 cultures. J Immunol. 2012;189:4331-7 pubmed publisher
Sahlander K, Larsson K, Palmberg L. Daily exposure to dust alters innate immunity. PLoS ONE. 2012;7:e31646 pubmed publisher
Kamekura R, Kojima T, Takano K, Go M, Sawada N, Himi T. The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis. Clin Exp Allergy. 2012;42:218-28 pubmed publisher
Yasuo T, Kitaya K. Effect of ovarian steroids on gene expression profile in human uterine microvascular endothelial cells. Fertil Steril. 2009;92:709-21 pubmed publisher

image

image 1 :

IFN-? Secretion Induced by IL-33 and Neutralization by Human ST2/IL-33 R Antibody.

product information

brand :

R&D Systems

master code :

MAB523

SKU :

MAB523-100

product name :

ST2/IL-33R Antibody

description :

The Human ST2/IL-33R Antibody from R&D Systems is a mouse monoclonal antibody to ST2/IL-33R. This antibody reacts with human. The Human ST2/IL-33R Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

ST2/IL-33R

category :

Primary Antibodies

unit sizes :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

97203

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human ST2/IL-33 R, Lys19-Phe328, Accession # BAA02233

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human ST2/IL-33 R in ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse ST2L, recombinant human (rh) IL-1 RI, rhIL-1 RII, rhIL-1 RA, rhIL-1 alpha , or rhIL-1 beta is observed.

gene symbol :

IL1RL1

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

BAA02233

applications :

Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)

USD :

448 USD

alt names :

DER4, DER4ST2growth stimulation-expressed, FIT-1, IL-1 R4, IL1R4, IL-1R4, IL-1RL1, IL-33 R, IL33R, IL-33R, interleukin 1 receptor-like 1, interleukin 1 receptor-related protein, interleukin-1 receptor-like 1, Ly84, MGC32623, Protein ST2, ST2L, ST2V, T1, T1homolog of mouse growth stimulation-expressed

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage