Mouse Uromodulin Antibody | R&D Systems MAB5175 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Uromodulin Antibody

catalog :

MAB5175

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

774056

reactivity :

mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; loading ...; fig 1A	Kemter E, Frohlich T, Arnold G, Wolf E, Wanke R. Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD). Sci Rep. 2017;7:42970 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:250; fig 6	Rieger A, Kemter E, Kumar S, Popper B, Aigner B, Wolf E, et al. Missense Mutation of POU Domain Class 3 Transcription Factor 3 in Pou3f3L423P Mice Causes Reduced Nephron Number and Impaired Development of the Thick Ascending Limb of the Loop of Henle. PLoS ONE. 2016;11:e0158977 pubmed publisher
	Kumar S, Fan X, Rasouly H, Sharma R, Salant D, Lu W. ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis. JCI Insight. 2023;8: pubmed publisher
	Lauver M, Jin G, Ayers K, Carey S, Specht C, Abendroth C, et al. T cell deficiency precipitates antibody evasion and emergence of neurovirulent polyomavirus. elife. 2022;11: pubmed publisher
	Khalil R, Simitsidellis I, Kim N, Jardí F, Schollaert D, Deboel L, et al. Androgen action on renal calcium and phosphate handling: Effects of bisphosphonate treatment and low calcium diet. Mol Cell Endocrinol. 2020;514:110891 pubmed publisher
	Xu C, Wang L, Zhang Y, Li W, Li J, Wang Y, et al. Tubule-Specific Mst1/2 Deficiency Induces CKD via YAP and Non-YAP Mechanisms. J Am Soc Nephrol. 2020;31:946-961 pubmed publisher
	Fujiki T, Ando F, Murakami K, Isobe K, Mori T, Susa K, et al. Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation. Sci Rep. 2019;9:9245 pubmed publisher
	Puri P, Schaefer C, Bushnell D, Taglienti M, Kreidberg J, Yoder B, et al. Ectopic Phosphorylated Creb Marks Dedifferentiated Proximal Tubules in Cystic Kidney Disease. Am J Pathol. 2018;188:84-94 pubmed publisher
	Naiman N, Fujioka K, Fujino M, Valerius M, Potter S, McMahon A, et al. Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017;41:349-365.e3 pubmed publisher
	Matsumura T, Sugawara Y, Yutani M, Amatsu S, Yagita H, Kohda T, et al. Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity. Nat Commun. 2015;6:6255 pubmed publisher

product information

master code :

MAB5175

SKU :

MAB5175

product name :

Mouse Uromodulin Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Uromodulin Antibody from R&D Systems is a rat monoclonal antibody to Uromodulin. This antibody reacts with mouse. The Mouse Uromodulin Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.

target :

Uromodulin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

774056

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Uromodulin, Ser24-Ala618, Accession # Q91X17

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse Uromodulin in direct ELISAs and Western blots. In direct ELISAs, 100% cross-reactivity with recombinant human Uromodulin is observed.

gene symbol :

UMOD

top caption :

Detection of Mouse Uromodulin antibody by Western Blot.

accessionNumbers :

Q91X17

applications :

Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen

USD :

439 USD

alt names :

ADMCKD2, FJHN, HNFJ, HNFJ1, MCKD2, Tamm-Horsfall glycoprotein, Tamm-Horsfall urinary glycoprotein, THGP, THP, UMOD, uromodulin, uromodulin (uromucoid, Tamm-Horsfall glycoprotein), uromucoid

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage