product summary
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company name :
R&D Systems
product type :
antibody
product name :
Rat IL-6 Antibody
catalog :
MAB5061-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
479 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
53324
reactivity :
human, rat
application :
western blot, immunohistochemistry, neutralization
more info or order :
citations: 5
Reference
Oh S, Lee H, Ki Y, Kim S, Lim K, Jung K. Gabexate mesilate ameliorates the neuropathic pain in a rat model by inhibition of proinflammatory cytokines and nitric oxide pathway via suppression of nuclear factor-κB. Korean J Pain. 2020;33:30-39 pubmed publisher
Lu W, Albalawi F, Beckel J, Lim J, Laties A, Mitchell C. The P2X7 receptor links mechanical strain to cytokine IL-6 up-regulation and release in neurons and astrocytes. J Neurochem. 2017;141:436-448 pubmed publisher
Shi X, Liu J, Yang T, Zhang Y, Li T, Chen J. TLR2/NF?B signalling regulates endogenous IL-6 release from marrow-derived mesenchymal stromal cells to suppress the apoptosis of PC12 cells injured by oxygen and glucose deprivation. Mol Med Rep. 2016;13:5358-64 pubmed publisher
Brochu M, Girard S, Lavoie K, Sebire G. Developmental regulation of the neuroinflammatory responses to LPS and/or hypoxia-ischemia between preterm and term neonates: An experimental study. J Neuroinflammation. 2011;8:55 pubmed publisher
Conant S, Swanborg R. Autoreactive T cells persist in rats protected against experimental autoimmune encephalomyelitis and can be activated through stimulation of innate immunity. J Immunol. 2004;172:5322-8 pubmed
product information
master code :
MAB5061
SKU :
MAB5061-100
product name :
Rat IL-6 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Rat IL-6 Antibody from R&D Systems is a mouse monoclonal antibody to IL-6. This antibody reacts with rat. The Rat IL-6 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Neutralization.
target :
IL-6
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
53324
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant rat IL-6, Phe25-Thr211, Accession # P20607.1
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Rat
specificity :
Detects recombinant rat IL-6 in direct ELISAs and Western blots.
gene symbol :
IL6
accessionNumbers :
P20607.1
applications :
Western Blot,Immunohistochemistry,Neutralization
USD :
479 USD
alt names :
B-cell differentiation factor, B-cell stimulatory factor 2, BSF2, BSF-2, CDF, CTL differentiation factor, HSF, hybridoma growth factor, IFNB2, IFN-beta-2, IL6, IL-6, Interferon beta-2, interleukin 6 (interferon, beta 2), interleukin BSF-2, interleukin-6, MGI-2A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.