Human/Mouse BMPR-IB/ALK-6 Antibody | R&D Systems MAB505 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse BMPR-IB/ALK-6 Antibody

catalog :

MAB505

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

88614

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; fig s2b	Veschi V, Mangiapane L, Nicotra A, Di Franco S, Scavo E, Apuzzo T, et al. Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant. Oncogene. 2020;39:987-1003 pubmed publisher
	Beckham J, Tuttle K, Tyler K. Reovirus activates transforming growth factor beta and bone morphogenetic protein signaling pathways in the central nervous system that contribute to neuronal survival following infection. J Virol. 2009;83:5035-45 pubmed publisher
	Sengle G, Ono R, Lyons K, Bachinger H, Sakai L. A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. J Mol Biol. 2008;381:1025-39 pubmed publisher
	Southwood M, Jeffery T, Yang X, Upton P, Hall S, Atkinson C, et al. Regulation of bone morphogenetic protein signalling in human pulmonary vascular development. J Pathol. 2008;214:85-95 pubmed
	Alejandre Alcazar M, Kwapiszewska G, Reiss I, Amarie O, Marsh L, Sevilla Pérez J, et al. Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2007;292:L537-49 pubmed
	Bleuming S, Kodach L, Garcia Leon M, Richel D, Peppelenbosch M, Reitsma P, et al. Altered bone morphogenetic protein signalling in the Helicobacter pylori-infected stomach. J Pathol. 2006;209:190-7 pubmed
	Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller E. Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res. 2005;65:8274-85 pubmed

product information

brand :

R&D Systems

master code :

MAB505

SKU :

MAB505-100

product name :

Human/Mouse BMPR-IB/ALK-6 Antibody

description :

The Human/Mouse BMPR-IB/ALK-6 Antibody from R&D Systems is a mouse monoclonal antibody to BMPR-IB/ALK-6. This antibody reacts with human, mouse. The Human/Mouse BMPR-IB/ALK-6 Antibody has been validated for the following applications: Western Blot.

target :

BMPR-IB/ALK-6

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

88614

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human BMPR-IB/ALK-6

isotype :

IgG2a

purity :

Protein A or G purified from ascites

species :

Human, Mouse

specificity :

Detects human and mouse BMPR-IB/ALK-6 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant mouse (rm) BMPR-IB and no cross-reactivity with recombinant human (rh) BMPR-IA, rmBMPR-IA, or rhBMPR-II is observed.

gene symbol :

BMPR1B

catalog number base :

MAB505

applications :

Western Blot

2020 USD :

339

2021 USD :

359 USD

alt names :

activin receptor-like kinase 6, ALK-6, ALK6CDw293, BMP type-1B receptor, BMPR1B, BMPR-1B, BMPRIB, bone morphogenetic protein receptor type-1B, bone morphogenetic protein receptor, type IB, CDw293, CDw293 antigen, EC 2.7.11, EC 2.7.11.30, serine/threonine receptor kinase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.