product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CXCL16 Antibody
catalog :
MAB503-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
459 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
142417
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, neutralization, flow cytometry, blocking or activating experiments
more info or order :
R&D Systems product webpage
citations: 17
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; ; fig 2e
Li D, Li J, Liu H, Zhai L, Hu W, Xia N, et al. Pathogenic Tconvs promote inflammatory macrophage polarization through GM-CSF and exacerbate abdominal aortic aneurysm formation. FASEB J. 2022;36:e22172 pubmed publisher
Koya J, Tanigawa T, Mizuno K, Kim H, Ito Y, Yuasa M, et al. Modeling NK-cell lymphoma in mice reveals its cell-of-origin and microenvironmental changes and identifies therapeutic targets. Nat Commun. 2024;15:9106 pubmed publisher
Rakebrandt N, Yassini N, Kolz A, Schorer M, Lambert K, Goljat E, et al. Innate acting memory Th1 cells modulate heterologous diseases. Proc Natl Acad Sci U S A. 2024;121:e2312837121 pubmed publisher
Broquet A, Gourain V, Goronflot T, Le Mabecque V, Sinha D, Ashayeripanah M, et al. Sepsis-trained macrophages promote antitumoral tissue-resident T cells. Nat Immunol. 2024;25:802-819 pubmed publisher
D xed ez S xe1 nchez A, Lindholm H, Vornewald P, Ostrop J, Yao R, Single A, et al. LSD1 drives intestinal epithelial maturation and controls small intestinal immune cell composition independent of microbiota in a murine model. Nat Commun. 2024;15:3412 pubmed publisher
Gnirck A, Philipp M, Waterh xf6 lter A, Wunderlich M, Shaikh N, Adamiak V, et al. Mucosal-associated invariant T cells contribute to suppression of inflammatory myeloid cells in immune-mediated kidney disease. Nat Commun. 2023;14:7372 pubmed publisher
Palakurthi B, Fross S, Guldner I, Aleksandrovic E, Liu X, Martino A, et al. Targeting CXCL16 and STAT1 augments immune checkpoint blockade therapy in triple-negative breast cancer. Nat Commun. 2023;14:2109 pubmed publisher
du Halgouet A, Darbois A, Alkobtawi M, Mestdagh M, Alphonse A, Premel V, et al. Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing. Immunity. 2023;56:78-92.e6 pubmed publisher
Klapproth E, Witt A, Klose P, Wiedemann J, Vavilthota N, K xfc nzel S, et al. Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction. Nat Commun. 2022;13:7648 pubmed publisher
Rosen S, Soung A, Yang W, Ai S, Kanmogne M, Dav xe9 V, et al. Single-cell RNA transcriptome analysis of CNS immune cells reveals CXCL16/CXCR6 as maintenance factors for tissue-resident T cells that drive synapse elimination. Genome Med. 2022;14:108 pubmed publisher
Jarade A, Garcia Z, Marie S, Demera A, Prinz I, Bousso P, et al. Inflammation triggers ILC3 patrolling of the intestinal barrier. Nat Immunol. 2022;23:1317-1323 pubmed publisher
Chen Y, Yang S, Tavormina J, Tampe D, Zeisberg M, Wang H, et al. Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer. Cancer Cell. 2022;40:818-834.e9 pubmed publisher
Catalano S, Panza S, Augimeri G, Giordano C, Malivindi R, Gelsomino L, et al. Phosphodiesterase 5 (PDE5) Is Highly Expressed in Cancer-Associated Fibroblasts and Enhances Breast Tumor Progression. Cancers (Basel). 2019;11: pubmed publisher
Lepore F, D Alessandro G, Antonangeli F, Santoro A, Esposito V, Limatola C, et al. CXCL16/CXCR6 Axis Drives Microglia/Macrophages Phenotype in Physiological Conditions and Plays a Crucial Role in Glioma. Front Immunol. 2018;9:2750 pubmed publisher
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed publisher
Wu T, Xie C, Bhaskarabhatla M, Yan M, Leone A, Chen S, et al. Excreted urinary mediators in an animal model of experimental immune nephritis with potential pathogenic significance. Arthritis Rheum. 2007;56:949-59 pubmed
Gough P, Garton K, Wille P, Rychlewski M, Dempsey P, Raines E. A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16. J Immunol. 2004;172:3678-85 pubmed
product information
master code :
MAB503
SKU :
MAB503-100
product name :
Mouse CXCL16 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Mouse CXCL16 Antibody from R&D Systems is a rat monoclonal antibody to CXCL16. This antibody reacts with mouse,transgenic mouse. The Mouse CXCL16 Antibody has been validated for the following applications: Neutralization,In vivo assay,ELISA Development,Luminex Development,Flow Cytometry,Western Blot,Immunohistochemistry,ELISA Capture (Matched Antibody Pair).
target :
CXCL16
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
142417
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse CXCL16, Asn27-Pro114, Accession # Q8BSU2
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse,Transgenic Mouse
specificity :
Detects mouse CXCL16 in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human CXCL1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, recombinant mouse CXCL1, 2, 6, 9, 10, 11, 12, 13, 14, 15, recombinant rat CXCL1, 2, 3, 5, or recombinant porcine CXCL8 is observed.
gene symbol :
CXCL16
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Chemotaxis Induced by CXCL16 and Neutralization by Mouse CXCL16 Antibody.
accessionNumbers :
Q8BSU2
applications :
Neutralization,In vivo assay,ELISA Development,Luminex Development,Flow Cytometry,Western Blot,Immunohistochemistry,ELISA Capture (Matched Antibody Pair)
USD :
459 USD
alt names :
chemokine (C-X-C motif) ligand 16, CXC chemokine ligand 16, CXCL16, CXCLG16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, SCYB16, Small-inducible cytokine B16, SRPSOXC-X-C motif chemokine 16, SR-PSOXTransmembrane chemokine CXCL16
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.