Mouse IFN-gamma Antibody | R&D Systems MAB485 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IFN-gamma Antibody

catalog :

MAB485

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

37895

reactivity :

human, mouse

application :

western blot, neutralization, blocking or activating experiments

citations: 19

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse; loading ...; fig s5c	Weiss J, Chen W, Nyuydzefe M, Trzeciak A, Flynn R, Tonra J, et al. ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings. Sci Signal. 2016;9:ra73 pubmed publisher
	Yang J, Kalim K, Li Y, Zheng Y, Guo F. Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation. J Leukoc Biol. 2019;106:1139-1151 pubmed publisher
	Nam Y, Jung S, Rim Y, Jung H, Lee K, Park N, et al. Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis. PLoS ONE. 2018;13:e0198740 pubmed publisher
	Lei W, Zeng D, Liu G, Zhu Y, Wang J, Wu H, et al. Crucial role of OX40/OX40L signaling in a murine model of asthma. Mol Med Rep. 2018;17:4213-4220 pubmed publisher
	Hu Y, Lao L, Mao J, Jin W, Luo H, Charpentier T, et al. Armc5 deletion causes developmental defects and compromises T-cell immune responses. Nat Commun. 2017;8:13834 pubmed publisher
	He W, Yang C, Xia L, Zhao M, Ge R, Huang H, et al. CD4(+) T cells from food allergy model are resistant to TCR-dependent apoptotic induction. Cytokine. 2014;68:32-9 pubmed publisher
	Yoo H, Choi Y, Ahn N, Lee S, Kim W, Jang M, et al. Transcriptional regulator CTR9 inhibits Th17 differentiation via repression of IL-17 expression. J Immunol. 2014;192:1440-8 pubmed publisher
	Jin W, Qi S, Luo H. The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function. BMC Immunol. 2011;12:68 pubmed publisher
	Sarra M, Caruso R, Cupi M, Monteleone I, Stolfi C, Campione E, et al. IL-21 promotes skin recruitment of CD4(+) cells and drives IFN-?-dependent epidermal hyperplasia. J Immunol. 2011;186:5435-42 pubmed publisher
	Jones G, Stumhofer J, Foster T, Twohig J, Hertzog P, Topley N, et al. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J. 2011;25:409-19 pubmed publisher
	Horvat J, Starkey M, Kim R, Beagley K, Preston J, Gibson P, et al. Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease. J Immunol. 2010;184:4159-69 pubmed publisher
	Deepak P, Kumar S, Kishore D, Acharya A. IL-13 from Th2-type cells suppresses induction of antigen-specific Th1 immunity in a T-cell lymphoma. Int Immunol. 2010;22:53-63 pubmed publisher
	McKinley L, Alcorn J, Peterson A, Dupont R, Kapadia S, Logar A, et al. TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J Immunol. 2008;181:4089-97 pubmed
	Mabalirajan U, Dinda A, Kumar S, Roshan R, Gupta P, Sharma S, et al. Mitochondrial structural changes and dysfunction are associated with experimental allergic asthma. J Immunol. 2008;181:3540-8 pubmed
	Iwanami K, Matsumoto I, Tanaka Watanabe Y, Inoue A, Mihara M, Ohsugi Y, et al. Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase. Arthritis Rheum. 2008;58:754-63 pubmed publisher
	Nakamura M, Jo J, Tabata Y, Ishikawa O. Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (Alopecia Areata) in a C3H/HeJ mouse model. Am J Pathol. 2008;172:650-8 pubmed publisher
	Smith S, Li J, Garbett K, Mirnics K, Patterson P. Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci. 2007;27:10695-702 pubmed
	Haraguchi G, Suzuki J, Kosuge H, Ogawa M, Koga N, Muto S, et al. A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model. J Mol Cell Cardiol. 2006;41:885-92 pubmed
	Kamath A, Sheasby C, Tough D. Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN-alpha beta and IFN-gamma. J Immunol. 2005;174:767-76 pubmed

product information

brand :

R&D Systems

master code :

MAB485

SKU :

MAB485-100

product name :

Mouse IFN-gamma Antibody

description :

The Mouse IFN-gamma Antibody from R&D Systems is a rat monoclonal antibody to IFN-gamma. This antibody reacts with mouse. The Mouse IFN-gamma Antibody has been validated for the following applications: Western Blot, Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-ready.

target :

IFN-gamma

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

37895

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse IFN-gamma

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse IFN-gamma in Western blots. In Western blots, this antibody does not cross-react with recombinant human (rh) IFN-gamma , rrIFN-gamma , rpIFN-gamma , rrmIFN-gamma , rfeIFN-gamma , or rcaIFN-gamma .

gene symbol :

IFNG

details of functionality :

ActivityAssaywCitation not found None None None

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB485

applications :

Western Blot, Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-ready

2020 USD :

339

2021 USD :

369 USD

alt names :

IFG, IFI, IFNG, IFNgamma, IFN-gamma, Immune interferon, interferon gamma, interferon, gamma

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.