product summary
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company name :
R&D Systems
product type :
antibody
product name :
IFN-gamma Antibody
catalog :
MAB485-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
453 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
37895
reactivity :
mouse
application :
western blot, neutralization
more info or order :
R&D Systems product webpage
citations: 20
Reference
Zhao T, Liu S, Ding X, Johnson E, Hanna N, Singh K, et al. Lysosomal acid lipase, CSF1R, and PD-L1 determine functions of CD11c+ myeloid-derived suppressor cells. JCI Insight. 2022;7: pubmed publisher
Napier R, Lee E, Davey M, Vance E, Furtado J, Snow P, et al. T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis. Nat Commun. 2020;11:5406 pubmed publisher
Yang J, Kalim K, Li Y, Zheng Y, Guo F. Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation. J Leukoc Biol. 2019;106:1139-1151 pubmed publisher
Nam Y, Jung S, Rim Y, Jung H, Lee K, Park N, et al. Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis. PLoS ONE. 2018;13:e0198740 pubmed publisher
Lei W, Zeng D, Liu G, Zhu Y, Wang J, Wu H, et al. Crucial role of OX40/OX40L signaling in a murine model of asthma. Mol Med Rep. 2018;17:4213-4220 pubmed publisher
Hu Y, Lao L, Mao J, Jin W, Luo H, Charpentier T, et al. Armc5 deletion causes developmental defects and compromises T-cell immune responses. Nat Commun. 2017;8:13834 pubmed publisher
He W, Yang C, Xia L, Zhao M, Ge R, Huang H, et al. CD4(+) T cells from food allergy model are resistant to TCR-dependent apoptotic induction. Cytokine. 2014;68:32-9 pubmed publisher
Yoo H, Choi Y, Ahn N, Lee S, Kim W, Jang M, et al. Transcriptional regulator CTR9 inhibits Th17 differentiation via repression of IL-17 expression. J Immunol. 2014;192:1440-8 pubmed publisher
Jin W, Qi S, Luo H. The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function. BMC Immunol. 2011;12:68 pubmed publisher
Sarra M, Caruso R, Cupi M, Monteleone I, Stolfi C, Campione E, et al. IL-21 promotes skin recruitment of CD4(+) cells and drives IFN-?-dependent epidermal hyperplasia. J Immunol. 2011;186:5435-42 pubmed publisher
Jones G, Stumhofer J, Foster T, Twohig J, Hertzog P, Topley N, et al. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J. 2011;25:409-19 pubmed publisher
Horvat J, Starkey M, Kim R, Beagley K, Preston J, Gibson P, et al. Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease. J Immunol. 2010;184:4159-69 pubmed publisher
Deepak P, Kumar S, Kishore D, Acharya A. IL-13 from Th2-type cells suppresses induction of antigen-specific Th1 immunity in a T-cell lymphoma. Int Immunol. 2010;22:53-63 pubmed publisher
McKinley L, Alcorn J, Peterson A, Dupont R, Kapadia S, Logar A, et al. TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J Immunol. 2008;181:4089-97 pubmed
Mabalirajan U, Dinda A, Kumar S, Roshan R, Gupta P, Sharma S, et al. Mitochondrial structural changes and dysfunction are associated with experimental allergic asthma. J Immunol. 2008;181:3540-8 pubmed
Iwanami K, Matsumoto I, Tanaka Watanabe Y, Inoue A, Mihara M, Ohsugi Y, et al. Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase. Arthritis Rheum. 2008;58:754-63 pubmed publisher
Nakamura M, Jo J, Tabata Y, Ishikawa O. Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (Alopecia Areata) in a C3H/HeJ mouse model. Am J Pathol. 2008;172:650-8 pubmed publisher
Smith S, Li J, Garbett K, Mirnics K, Patterson P. Maternal immune activation alters fetal brain development through interleukin-6. J Neurosci. 2007;27:10695-702 pubmed
Haraguchi G, Suzuki J, Kosuge H, Ogawa M, Koga N, Muto S, et al. A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model. J Mol Cell Cardiol. 2006;41:885-92 pubmed
Kamath A, Sheasby C, Tough D. Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN-alpha beta and IFN-gamma. J Immunol. 2005;174:767-76 pubmed
image
image 1 :
R&D Systems MAB485-100 image 1
Detection of IFN-? antibody in Mouse Splenoctyes antibody by Flow Cytometry.
product information
brand :
R&D Systems
master code :
MAB485
SKU :
MAB485-100
product name :
IFN-gamma Antibody
description :
The Mouse IFN-gamma Antibody from R&D Systems is a rat monoclonal antibody to IFN-gamma. This antibody reacts with mouse. The Mouse IFN-gamma Antibody has been validated for the following applications: Western Blot, Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-ready.
target :
IFN-gamma
category :
Primary Antibodies
unit sizes :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
37895
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse IFN-gamma
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse IFN-gamma in Western blots. In Western blots, this antibody does not cross-react with recombinant human (rh) IFN-gamma , rrIFN-gamma , rpIFN-gamma , rrmIFN-gamma , rfeIFN-gamma , or rcaIFN-gamma .
gene symbol :
IFNG
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
applications :
Western Blot, Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-ready
USD :
453 USD
alt names :
IFG, IFI, IFNG, IFNgamma, IFN-gamma, Immune interferon, interferon gamma, interferon, gamma
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.