Human GRP78/HSPA5 Antibody | R&D Systems MAB4846 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human GRP78/HSPA5 Antibody

catalog :

MAB4846

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

474421

reactivity :

human, zebrafish

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 14

Reference
Ennis A, Wang L, Wang X, Yu C, Saidi L, Xu Y, et al. NEMF-mediated CAT-tailing defines distinct branches of translocation-associated quality control. bioRxiv. 2024;: pubmed publisher
Wang L, Xu Y, Yun S, Yuan Q, Satpute Krishnan P, Ye Y. SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum. Cell Rep. 2023;42:112028 pubmed publisher
Tissarinen P, Tiensuu H, Haapalainen A, M xe4 xe4 tt xe4 T, Ojaniemi M, Hallman M, et al. Elevated human placental heat shock protein 5 is associated with spontaneous preterm birth. Pediatr Res. 2023;94:520-529 pubmed publisher
de la Cruz Ojeda P, Schmid T, Boix L, Moreno M, Sapena V, Praena Fern xe1 ndez J, et al. miR-200c-3p, miR-222-5p, and miR-512-3p Constitute a Biomarker Signature of Sorafenib Effectiveness in Advanced Hepatocellular Carcinoma. Cells. 2022;11: pubmed publisher
Weldemariam M, Woo J, Zhang Q. Pancreatic INS-1 β-Cell Response to Thapsigargin and Rotenone: A Comparative Proteomics Analysis Uncovers Key Pathways of β-Cell Dysfunction. Chem Res Toxicol. 2022;35:1080-1094 pubmed publisher
Tsai Y, Jeng K, He M, Hsieh Y, Lai H, Lai C, et al. MXD3 Promotes Obesity and the Androgen Receptor Signaling Pathway in Gender-Disparity Hepatocarcinogenesis. Cells. 2021;10: pubmed publisher
Chu H, Shuai H, Hou Y, Zhang X, Wen L, Huang X, et al. Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity. Sci Adv. 2021;7: pubmed publisher
Horibe T, Torisawa A, Masuda Y, Kawakami K. Functional analysis of protein disulfide isomerase P5 in glioblastoma cells as a novel anticancer target. Oncol Rep. 2019;41:961-972 pubmed publisher
Chu H, Chan C, Zhang X, Wang Y, Yuan S, Zhou J, et al. Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells. J Biol Chem. 2018;293:11709-11726 pubmed publisher
Janczar S, Nautiyal J, Xiao Y, Curry E, Sun M, Zanini E, et al. WWOX sensitises ovarian cancer cells to paclitaxel via modulation of the ER stress response. Cell Death Dis. 2017;8:e2955 pubmed publisher
Banerjee A, Ahmed H, Yang P, Czinn S, Blanchard T. Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment. Oncotarget. 2016;7:41432-41444 pubmed publisher
Shi L, Gehin T, Chevolot Y, Souteyrand E, MangÃ© A, Solassol J, et al. Anti-heat shock protein autoantibody profiling in breast cancer using customized protein microarray. Anal Bioanal Chem. 2016;408:1497-506 pubmed publisher
Kulkarni Y, Klinke D. Protein-based identification of quantitative trait loci associated with malignant transformation in two HER2+ cellular models of breast cancer. Proteome Sci. 2012;10:11 pubmed publisher
Buchkovich N, Maguire T, Paton A, Paton J, Alwine J. The endoplasmic reticulum chaperone BiP/GRP78 is important in the structure and function of the human cytomegalovirus assembly compartment. J Virol. 2009;83:11421-8 pubmed publisher

product information

master code :

MAB4846

SKU :

MAB4846

product name :

Human GRP78/HSPA5 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human GRP78/HSPA5 Antibody from R&D Systems is a mouse monoclonal antibody to GRP78/HSPA5. This antibody reacts with human,fish - danio rerio (zebrafish). The Human GRP78/HSPA5 Antibody has been validated for the following applications: Western Blot,Immunoprecipitation,Immunocytochemistry,Simple Western.

target :

GRP78/HSPA5

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

474421

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human GRP78, Met1-Leu654, Accession # P11021

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Fish - Danio rerio (Zebrafish)

specificity :

Detects endogenous human GRP78 at 78 kDa in Western blots.

gene symbol :

HSPA5

top caption :

Detection of Human GRP78/HSPA5 antibody by Western Blot.

accessionNumbers :

P11021

applications :

Western Blot,Immunoprecipitation,Immunocytochemistry,Simple Western

USD :

469 USD

alt names :

78 kDa glucose-regulated protein, BiP, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, FLJ26106, GRP-78, GRP78BIP, Heat shock 70 kDa protein 5, heat shock 70kD protein 5 (glucose-regulated protein, 78kD), heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa), HSP70-5, HSPA5, Immunoglobulin heavy chain-binding protein, MIF2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage