CD3 Antibody | R&D Systems MAB4841-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

CD3 Antibody

catalog :

MAB4841-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

448 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

17A2

reactivity :

mouse

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 28

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 5c	Li D, Peng J, Li T, Liu Y, Chen M, Shi X. Itgb3-integrin-deficient mice may not be a sufficient model for patients with Glanzmann thrombasthenia. Mol Med Rep. 2021;23: pubmed publisher
	Cha J, Chan L, Wang Y, Chu Y, Wang C, Lee H, et al. Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer. J Biol Chem. 2022;298:101817 pubmed publisher
	Zhang Z, Na H, Gan Q, Tao Q, Alekseyev Y, Hu J, et al. Monomeric C-reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype-dependent pattern: A risk factor for Alzheimer's disease?. Aging Cell. 2021;20:e13501 pubmed publisher
	Zhou J, Zhang N, Zhang W, Lu C, Xu F. The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiation. Cell Biosci. 2021;11:84 pubmed publisher
	Kim Y, Gautam S, Aseer K, Kim J, Chandrasekaran P, Mazucanti C, et al. Hepatocyte cannabinoid 1 receptor nullification alleviates toxin-induced liver damage via NF-κB signaling. Cell Death Dis. 2020;11:1044 pubmed publisher
	Alvarez C, Suliman S, Almarhoumi R, Vega M, Rojas C, Monasterio G, et al. Regulatory T cell phenotype and anti-osteoclastogenic function in experimental periodontitis. Sci Rep. 2020;10:19018 pubmed publisher
	Chida J, Hara H, Uchiyama K, Takahashi E, Miyata H, Kosako H, et al. Prion protein signaling induces M2 macrophage polarization and protects from lethal influenza infection in mice. PLoS Pathog. 2020;16:e1008823 pubmed publisher
	Xu Y, Lv L, Liu Y, Smith M, Li W, Tan X, et al. Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy. J Clin Invest. 2019;130: pubmed publisher
	Wen L, Lu H, Li Q, Li Q, Wen S, Wang D, et al. Contributions of T cell dysfunction to the resistance against anti-PD-1 therapy in oral carcinogenesis. J Exp Clin Cancer Res. 2019;38:299 pubmed publisher
	Wu J, Gu J, Zhou S, Lu H, Lu Y, Lu L, et al. Anti-IL-22 Antibody Attenuates Acute Graft-versus-Host Disease via Increasing Foxp3+ T Cell through Modulation of CD11b+ Cell Function. J Immunol Res. 2018;2018:1605341 pubmed publisher
	Deyhle M, Hafen P, Parmley J, Preece C, Robison M, Sorensen J, et al. CXCL10 increases in human skeletal muscle following damage but is not necessary for muscle regeneration. Physiol Rep. 2018;6:e13689 pubmed publisher
	Chauhan P, Sheng W, Hu S, Prasad S, Lokensgard J. Nitrosative damage during retrovirus infection-induced neuropathic pain. J Neuroinflammation. 2018;15:66 pubmed publisher
	Swirski S, Röger C, Pienkowska Schelling A, Ihlenburg C, Fischer G, May O, et al. A Novel C-Terminal Mutation in Gsdma3 (C+/H-) Leads to Alopecia and Corneal Inflammatory Response in Mice. Invest Ophthalmol Vis Sci. 2018;59:561-571 pubmed publisher
	Lei W, Zeng D, Liu G, Zhu Y, Wang J, Wu H, et al. Crucial role of OX40/OX40L signaling in a murine model of asthma. Mol Med Rep. 2018;17:4213-4220 pubmed publisher
	Fu X, Sun F, Wang F, Zhang J, Zheng B, Zhong J, et al. Aloperine Protects Mice against DSS-Induced Colitis by PP2A-Mediated PI3K/Akt/mTOR Signaling Suppression. Mediators Inflamm. 2017;2017:5706152 pubmed publisher
	Fischer R, Marsal J, Guttà C, Eisler S, Peters N, Bethea J, et al. Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2. Sci Rep. 2017;7:6607 pubmed publisher
	Pan W, Hao W, Shen Y, Li X, Wang Y, Sun F, et al. The excretory-secretory products of Echinococcus granulosus protoscoleces directly regulate the differentiation of B10, B17 and Th17 cells. Parasit Vectors. 2017;10:348 pubmed publisher
	Makker P, Duffy S, Lees J, Perera C, Tonkin R, Butovsky O, et al. Characterisation of Immune and Neuroinflammatory Changes Associated with Chemotherapy-Induced Peripheral Neuropathy. PLoS ONE. 2017;12:e0170814 pubmed publisher
	Maphis N, Jiang S, Xu G, Kokiko Cochran O, Roy S, Van Eldik L, et al. Selective suppression of the ? isoform of p38 MAPK rescues late-stage tau pathology. Alzheimers Res Ther. 2016;8:54 pubmed
	Li K, Fähnrich A, Roy E, Cuda C, Grimes H, PERLMAN H, et al. Temporal Expression of Bim Limits the Development of Agonist-Selected Thymocytes and Skews Their TCR? Repertoire. J Immunol. 2017;198:257-269 pubmed
	Ouyang M, White E, Ren H, Guo Q, Zhang I, Gao H, et al. Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model. PLoS ONE. 2016;11:e0148139 pubmed publisher
	Fan M, Zhang Y, Huang Z, Liu J, Guo X, Zhang H, et al. Optimizations of siRNA design for the activation of gene transcription by targeting the TATA-box motif. PLoS ONE. 2014;9:e108253 pubmed publisher
	Ahn B, Le H, Shin M, Bae S, Lee E, Wee H, et al. Ninjurin1 deficiency attenuates susceptibility of experimental autoimmune encephalomyelitis in mice. J Biol Chem. 2014;289:3328-38 pubmed publisher
	Nakamura T, Hamuro J, Takaishi M, Simmons S, Maruyama K, Zaffalon A, et al. LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis. J Clin Invest. 2014;124:385-97 pubmed publisher
	Xu C, Yu P, Han X, Du L, Gan J, Wang Y, et al. TGF-? promotes immune responses in the presence of mesenchymal stem cells. J Immunol. 2014;192:103-9 pubmed publisher
	Vang A, Housley W, Dong H, Basole C, Ben Sasson S, Kream B, et al. Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac. Biochem J. 2013;456:463-73 pubmed publisher
	De Palma A, Verbeken E, Van Aelst I, Van Den Steen P, Opdenakker G, Neyts J. Increased gelatinase B/matrix metalloproteinase 9 (MMP-9) activity in a murine model of acute coxsackievirus B4-induced pancreatitis. Virology. 2008;382:20-7 pubmed publisher
	Nguyen P, Moisini I, Geiger T. Identification of a murine CD28 dileucine motif that suppresses single-chain chimeric T-cell receptor expression and function. Blood. 2003;102:4320-5 pubmed

image

image 1 :

CD3 antibody in Mouse Splenocytes by Immunocytochemistry (ICC).

product information

brand :

R&D Systems

master code :

MAB4841

SKU :

MAB4841-100

product name :

CD3 Antibody

description :

The Mouse CD3 Antibody from R&D Systems is a rat monoclonal antibody to CD3. This antibody reacts with mouse. The Mouse CD3 Antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Complement-dependent Cytotoxicity, T Cell Stimulation, Immunocytochemistry, CyTOF-ready.

target :

CD3

category :

Primary Antibodies

unit sizes :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

17A2

conjugate :

Unconjugated

host :

Rat

immunogen :

T cell hybridoma D1

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Reacts with mouse TCR-associated CD3 complex that occurs on thymocytes and mature T cells.

gene symbol :

Cd247

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

applications :

Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Complement-dependent Cytotoxicity, T Cell Stimulation, Immunocytochemistry, CyTOF-ready

USD :

448 USD

alt names :

CD_antigen: CD3e, CD3 antigen, delta subunit, CD3d antigen, CD3d antigen, delta polypeptide (TiT3 complex), CD3d molecule, delta (CD3-TCR complex), CD3-DELTA, CD3e, CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, CD3G, CD3g antigen, CD3g antigen, gamma polypeptide (TiT3 complex), CD3g molecule, epsilon (CD3-TCR complex), CD3g molecule, gamma (CD3-TCR complex), CD3-GAMMA, FLJ17620, FLJ17664, FLJ18683, FLJ79544, FLJ94613, IMD18, MGC138597, T3DOKT3, delta chain, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell receptor T3 delta chain, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 delta chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage