CD3 epsilon Antibody | R&D Systems MAB484-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

CD3 epsilon Antibody

catalog :

MAB484-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

453 USD

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

145-2C11

reactivity :

mouse

application :

immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 18

Reference
Sidles S, Xiong Y, Young M, LaRue A. High-Fat Diet Alters Immunogenic Properties of Circulating and Adipose Tissue-Associated Myeloid-Derived CD45+DDR2+ Cells. Mediators Inflamm. 2019;2019:1648614 pubmed publisher
Visekruna A, Hartmann S, Sillke Y, Glauben R, Fischer F, Raifer H, et al. Intestinal development and homeostasis require activation and apoptosis of diet-reactive T cells. J Clin Invest. 2019;129:1972-1983 pubmed publisher
Engelowski E, Modares N, Gorressen S, Bouvain P, Semmler D, Alter C, et al. IL-23R Signaling Plays No Role in Myocardial Infarction. Sci Rep. 2018;8:17078 pubmed publisher
Savinko T, Guenther C, Uotila L, Llort Asens M, Yao S, Tojkander S, et al. Filamin A Is Required for Optimal T Cell Integrin-Mediated Force Transmission, Flow Adhesion, and T Cell Trafficking. J Immunol. 2018;200:3109-3116 pubmed publisher
Mantani P, Dunér P, Bengtsson E, Ljungcrantz I, Sundius L, To F, et al. Interleukin-25 (IL-25) has a protective role in atherosclerosis development in the aortic arch in mice. J Biol Chem. 2018;293:6791-6801 pubmed publisher
Johnson R, Yu H, Strank N, Karunakaran K, Zhu Y, Brunham R. B Cell Presentation of Chlamydia Antigen Selects Out Protective CD4?13 T Cells: Implications for Genital Tract Tissue-Resident Memory Lymphocyte Clusters. Infect Immun. 2018;86: pubmed publisher
McDonald L, Johnson S, Russell D, Young M, LaRue A. Role of a novel immune modulating DDR2-expressing population in silica-induced pulmonary fibrosis. PLoS ONE. 2017;12:e0180724 pubmed publisher
Chung J, Ebens C, Perkey E, Radojcic V, Koch U, Scarpellino L, et al. Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. J Clin Invest. 2017;127:1574-1588 pubmed publisher
Chen H, Wang P, Su H, Wang W, Chu Z, Zhang L, et al. mTORC2 controls Th9 polarization and allergic airway inflammation. Allergy. 2017;72:1510-1520 pubmed publisher
Kinosada H, Yasunaga J, Shimura K, Miyazato P, Onishi C, Iyoda T, et al. HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors. PLoS Pathog. 2017;13:e1006120 pubmed publisher
Gupta S, Marcel N, Talwar S, Garg M, R I, Perumalsamy L, et al. Developmental heterogeneity in DNA packaging patterns influences T-cell activation and transmigration. PLoS ONE. 2012;7:e43718 pubmed publisher
Jones G, Stumhofer J, Foster T, Twohig J, Hertzog P, Topley N, et al. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J. 2011;25:409-19 pubmed publisher
Jones G, McLoughlin R, Hammond V, Parker C, Williams J, Malhotra R, et al. Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. J Immunol. 2010;184:2130-9 pubmed publisher
Sinclair L, Finlay D, Feijoo C, Cornish G, Gray A, Ager A, et al. Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking. Nat Immunol. 2008;9:513-21 pubmed publisher
Li W, Kashiwamura S, Ueda H, Sekiyama A, Okamura H. Protection of CD8+ T cells from activation-induced cell death by IL-18. J Leukoc Biol. 2007;82:142-51 pubmed
Bheeshmachar G, Purushotaman D, Sade H, Gunasekharan V, Rangarajan A, Sarin A. Evidence for a role for notch signaling in the cytokine-dependent survival of activated T cells. J Immunol. 2006;177:5041-50 pubmed
Ogilvie R, Abelson M, Hau H, Vlasova I, Blackshear P, Bohjanen P. Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay. J Immunol. 2005;174:953-61 pubmed
Kipnis J, Cardon M, Avidan H, Lewitus G, Mordechay S, Rolls A, et al. Dopamine, through the extracellular signal-regulated kinase pathway, downregulates CD4+CD25+ regulatory T-cell activity: implications for neurodegeneration. J Neurosci. 2004;24:6133-43 pubmed

image

image 1 :

Mouse CD3e Antibody Stimulates Cell Proliferation antibody in Mouse T Cells.

product information

brand :

R&D Systems

master code :

MAB484

SKU :

MAB484-100

product name :

CD3 epsilon Antibody

description :

The Mouse CD3 epsilon Antibody from R&D Systems is a hamster monoclonal antibody to CD3 epsilon. This antibody reacts with mouse. The Mouse CD3 epsilon Antibody has been validated for the following applications: Flow Cytometry, Immunoprecipitation, Cell depletion, T Cell Stimulation, CyTOF-reported.

target :

CD3 epsilon

category :

Primary Antibodies

sizes available :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

145-2C11

conjugate :

Unconjugated

host :

Hamster

immunogen :

H-2Kb-specific mouse cytotoxic T-lymphocyte

isotype :

IgG

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse CD3 epsilon

gene symbol :

CD3E

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

applications :

Flow Cytometry, Immunoprecipitation, Cell depletion, T Cell Stimulation, CyTOF-reported

USD :

453 USD

alt names :

CD3e, CD3e antigen, CD3e antigen, epsilon polypeptide (TiT3 complex), CD3e molecule, epsilon (CD3-TCR complex), CD3-epsilon, FLJ18683, T3E, T-cell antigen receptor complex, epsilon subunit of T3, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, TCRE

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage