product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Integrin ▀8 Antibody
catalog :
MAB4775
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
416922
reactivity :
human
application :
flow cytometry
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:100; fig 2c
Malenica I, Adam J, Corgnac S, Mezquita L, Auclin E, Damei I, et al. Integrin-αV-mediated activation of TGF-β regulates anti-tumour CD8 T cell immunity and response to PD-1 blockade. Nat Commun. 2021;12:5209 pubmed publisher
Rouaud L, Baudin L, Gautier Isola M, Van Meerbeeck P, Feyereisen E, Blacher S, et al. Spatial Distribution of Non-Immune Cells Expressing Glycoprotein A Repetitions Predominant in Human and Murine Metastatic Lymph Nodes. Cancers (Basel). 2023;15: pubmed publisher
Yang C, Tian G, Dajac M, Doty A, Wang S, Lee J, et al. Slow-Cycling Cells in Glioblastoma: A Specific Population in the Cellular Mosaic of Cancer Stem Cells. Cancers (Basel). 2022;14: pubmed publisher
Desch A, Strozyk E, Bauer A, Huck V, Niemeyer V, Wieland T, et al. Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin ?v?5-induced secretion of VEGF-A. Am J Pathol. 2012;181:693-705 pubmed publisher
product information
master code :
MAB4775
SKU :
MAB4775
product name :
Human Integrin ▀8 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Integrin ß8 Antibody from R&D Systems is a mouse monoclonal antibody to Integrin beta 8. This antibody reacts with human. The Human Integrin ß8 Antibody has been validated for the following applications: Flow Cytometry,CyTOF-ready.
target :
Integrin beta 8
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
416922
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Integrin ▀8, Glu43-Arg684 (predicted), Accession # P26012
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Integrin ▀8 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Integrins ▀1, ▀2, ▀3, ▀4, ▀5, ▀6, ▀7, or recombinant mouse Integrin ▀8 is observed.
gene symbol :
ITGB8
top caption :
Detection of Integrin ss8 antibody in A172 Human Cell Line antibody by Flow Cytometry.
accessionNumbers :
P26012
applications :
Flow Cytometry,CyTOF-ready
USD :
469 USD
alt names :
integrin beta-8, integrin, beta 8, ITGB8
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.