Human/Mouse Wnt-4 Antibody | R&D Systems MAB4751 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse Wnt-4 Antibody

catalog :

MAB4751

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

55025

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; human	Garcia Castro B, Alvarez Zavala M, Riveros Magaña A, Ortiz Lazareno P, Ratkovich González S, Hernandez Flores G, et al. Restoration of WNT4 inhibits cell growth in leukemia-derived cell lines. BMC Cancer. 2013;13:557 pubmed publisher
	Yang L, Ruan Z, Lin X, Wang H, Xin Y, Tang H, et al. NAD+ dependent UPRmt activation underlies intestinal aging caused by mitochondrial DNA mutations. Nat Commun. 2024;15:546 pubmed publisher
	Sottnik J, Shackleford M, Robinson S, Villagomez F, Bahnassy S, Oesterreich S, et al. WNT4 regulates cellular metabolism via intracellular activity at the mitochondria in breast and gynecologic cancers. Cancer Res Commun. 2023;: pubmed publisher
	Sommerfeld L, Finkernagel F, Jansen J, Wagner U, Nist A, Stiewe T, et al. The multicellular signalling network of ovarian cancer metastases. Clin Transl Med. 2021;11:e633 pubmed publisher
	Samant S, Pillai V, Gupta M. Skeletal muscle-specific over-expression of the nuclear sirtuin SIRT6 blocks cancer-associated cachexia by regulating multiple targets. JCSM Rapid Commun. 2021;4:40-56 pubmed publisher
	Shackleford M, Rao D, Bordeaux E, Hicks H, Towers C, Sottnik J, et al. Estrogen Regulation of mTOR Signaling and Mitochondrial Function in Invasive Lobular Carcinoma Cell Lines Requires WNT4. Cancers (Basel). 2020;12: pubmed publisher
	Hung L, Johnson J, Ji Y, Christian D, Herbine K, Pastore C, et al. Cell-Intrinsic Wnt4 Influences Conventional Dendritic Cell Fate Determination to Suppress Type 2 Immunity. J Immunol. 2019;: pubmed publisher

product information

master code :

MAB4751

SKU :

MAB4751

product name :

Human/Mouse Wnt-4 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse Wnt-4 Antibody from R&D Systems is a rat monoclonal antibody to Wnt-4. This antibody reacts with human,mouse,transgenic mouse. The Human/Mouse Wnt-4 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,ELISA,Immunocytochemistry.

target :

Wnt-4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

55025

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse Wnt-4, Ile37-Glu76, Accession # NP_033549

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

This antibody detects human and mouse Wnt-4 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) Wnt-1, 2b, 5a, 5b, 8a, 8b, 9b, 10a, 10b, 11, 16, recombinant human (rh) Wnt-2, 3a, 7a, or 7b is observed. In sandwich immunoassays, this antibody is specific for human Wnt-4 as a capture antibody when paired with Sheep Anti-Human Wnt-4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6076 ).

gene symbol :

WNT4

top caption :

Detection of Human Wnt-4 antibody by Western Blot.

accessionNumbers :

NP_033549

applications :

Western Blot,Immunohistochemistry,ELISA,Immunocytochemistry

USD :

439 USD

alt names :

protein Wnt-4, SERKAL, wingless-type MMTV integration site family, member 4, Wnt4, WNT-4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage