VEGFR1/Flt-1 Antibody | R&D Systems MAB471-100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

VEGFR1/Flt-1 Antibody

catalog :

MAB471-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

479 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

141515

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 5e	Xie A, Iguchi N, Clarkson T, Malykhina A. Pharmacogenetic inhibition of lumbosacral sensory neurons alleviates visceral hypersensitivity in a mouse model of chronic pelvic pain. PLoS ONE. 2022;17:e0262769 pubmed publisher
	Sarkar J, Luo Y, Zhou Q, Ivakhnitskaia E, Lara D, Katz E, et al. VEGF receptor heterodimers and homodimers are differentially expressed in neuronal and endothelial cell types. PLoS ONE. 2022;17:e0269818 pubmed publisher
	Falero Perez J, Sheibani N, Sorenson C. Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells. PLoS ONE. 2020;15:e0232779 pubmed publisher
	Jamali N, Song Y, Sorenson C, Sheibani N. 1,25(OH)2D3 regulates the proangiogenic activity of pericyte through VDR-mediated modulation of VEGF production and signaling of VEGF and PDGF receptors. FASEB Bioadv. 2019;1:415-434 pubmed publisher
	Falero Perez J, Song Y, Zhao Y, Teixeira L, Sorenson C, Sheibani N. Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells. PLoS ONE. 2018;13:e0206756 pubmed publisher
	Selvaraj D, Gangadharan V, Michalski C, Kurejova M, StÃ¶sser S, Srivastava K, et al. A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain. Cancer Cell. 2015;27:780-96 pubmed publisher
	Yang Y, Ahn Y, Chen Y, Tan X, Guo L, Gibbons D, et al. ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism. J Clin Invest. 2014;124:2696-708 pubmed publisher
	Zechariah A, ElAli A, Doeppner T, Jin F, Hasan M, Helfrich I, et al. Vascular endothelial growth factor promotes pericyte coverage of brain capillaries, improves cerebral blood flow during subsequent focal cerebral ischemia, and preserves the metabolic penumbra. Stroke. 2013;44:1690-7 pubmed publisher
	Mir S, Jin L, Craven R. Neutrophil gelatinase-associated lipocalin (NGAL) expression is dependent on the tumor-associated sigma-2 receptor S2RPgrmc1. J Biol Chem. 2012;287:14494-501 pubmed publisher
	Suryawanshi A, Mulik S, Sharma S, Reddy P, Sehrawat S, Rouse B. Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor. J Immunol. 2011;186:3653-65 pubmed publisher
	Rosu A, Ciurea P, Simionescu C, Margaritescu C, Musetescu A, Ciurea R, et al. The study of angiogenesis in early rheumatoid arthritis--clinical, immunohistochemical and immunological correlations. J Med Life. 2008;1:287-94 pubmed
	Isayeva T, Chanda D, Kallman L, Eltoum I, Ponnazhagan S. Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model. Cancer Res. 2007;67:5789-97 pubmed

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

MAB471

SKU :

MAB471-100

product name :

VEGFR1/Flt-1 Antibody

description :

The Mouse VEGFR1/Flt-1 Antibody from R&D Systems is a rat monoclonal antibody to VEGFR1/Flt-1. This antibody reacts with human,mouse,rat. The Mouse VEGFR1/Flt-1 Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry.

target :

VEGFR1/Flt-1

unit size :

100 ug (also 25 ug, 500 ug)

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

141515

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse VEGFR1, Ser27-Glu759, Accession # P35969

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects mouse VEGFR1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human VEGFR1, recombinant mouse (rm) VEGFR2, or rmVEGFR3 is observed.

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

gene symbol :

FLT1

accessionNumbers :

P35969

applications :

Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry

product keywords :

MAB471, mVEGF R1 MAb Cl 141515, Rat Anti-Mouse VEGF R1/Flt-1 Monoclonal Antibody, Anti-VEGF R1, Anti-Flt-1, Rat Anti Mouse VEGF R1/Flt-1 Monoclonal Antibody, Anti-mVEGF R1, SC-316, VEGFR1, Flt1, Receptor Tyrosine Kinase, RTK, VEGFR1, VEGFR 1, VEGF Receptor 1, sFlt1, sFlt 1, sVEGF R1, sFlt-1, sVEGFR1, VEGF R 1, Fms Related Tyrosine Kinase 1, Vascular Endothelial Growth Factor Receptor 1, Tyrosine-Protein Kinase Receptor FLT, Fms-Like

USD :

459

USD 2025 :

479 USD

alt names :

EC 2.7.10, EC 2.7.10.1, FLT, FLT1, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1