Mouse CXCL13/BLC/BCA-1 Antibody | R&D Systems MAB470-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse CXCL13/BLC/BCA-1 Antibody

catalog :

MAB470-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

143614

reactivity :

human, mouse

application :

ELISA, neutralization, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 13

Reference
Ng K, Boumelha J, Enfield K, Almagro J, Cha H, Pich O, et al. Antibodies against endogenous retroviruses promote lung cancer immunotherapy. Nature. 2023;616:563-573 pubmed publisher
Singh S, Roszik J, Saini N, Singh V, Bavisi K, Wang Z, et al. B Cells Are Required to Generate Optimal Anti-Melanoma Immunity in Response to Checkpoint Blockade. Front Immunol. 2022;13:794684 pubmed publisher
Chaurio R, Anadon C, Lee Costich T, Payne K, Biswas S, Harro C, et al. TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures. Immunity. 2022;55:115-128.e9 pubmed publisher
Crichton E, Zeng S, La Muraglia G, Badell I. CXCL13 Is an Indicator of Germinal Center Activity and Alloantibody Formation Following Transplantation. Transplant Direct. 2021;7:e785 pubmed publisher
Ma L, Yu L, Jiang B, Wang J, Guo X, Huang Y, et al. ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons. J Exp Med. 2021;218: pubmed publisher
Klimatcheva E, Pandina T, Reilly C, Torno S, Bussler H, Scrivens M, et al. CXCL13 antibody for the treatment of autoimmune disorders. BMC Immunol. 2015;16:6 pubmed publisher
Ohama H, Asai A, Ito I, Suzuki S, Kobayashi M, Higuchi K, et al. M2b macrophage elimination and improved resistance of mice with chronic alcohol consumption to opportunistic infections. Am J Pathol. 2015;185:420-31 pubmed publisher
Kramer J, Klimatcheva E, Rothstein T. CXCL13 is elevated in Sjögren's syndrome in mice and humans and is implicated in disease pathogenesis. J Leukoc Biol. 2013;94:1079-89 pubmed publisher
Thomas S, Rutkowski J, Pasquier M, Kuan E, Alitalo K, Randolph G, et al. Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage. J Immunol. 2012;189:2181-90 pubmed publisher
León B, Ballesteros Tato A, Browning J, Dunn R, Randall T, Lund F. Regulation of T(H)2 development by CXCR5+ dendritic cells and lymphotoxin-expressing B cells. Nat Immunol. 2012;13:681-90 pubmed publisher
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed publisher
Weisel F, Appelt U, Schneider A, Horlitz J, Van Rooijen N, Korner H, et al. Unique requirements for reactivation of virus-specific memory B lymphocytes. J Immunol. 2010;185:4011-21 pubmed publisher
Henry R, Kendall P. CXCL13 blockade disrupts B lymphocyte organization in tertiary lymphoid structures without altering B cell receptor bias or preventing diabetes in nonobese diabetic mice. J Immunol. 2010;185:1460-5 pubmed publisher

product information

master code :

MAB470

SKU :

MAB470-100

product name :

Mouse CXCL13/BLC/BCA-1 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Mouse CXCL13/BLC/BCA-1 Antibody from R&D Systems is a rat monoclonal antibody to CXCL13/BLC/BCA-1. This antibody reacts with mouse. The Mouse CXCL13/BLC/BCA-1 Antibody has been validated for the following applications: Luminex Development,Neutralization,Direct ELISA,Cell Selection,Immunohistochemistry-Frozen,ELISA Capture (Matched Antibody Pair).

target :

CXCL13/BLC/BCA-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

143614

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse CXCL13, Ile22-Ala109, Accession # O55038

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse CXCL13 in ELISAs. In ELISAs, this antibody does not cross-react with recombinant human (rh) CXCL13, rmCXCL11/I-TAC, rmCXCL9/MIG, or rm CXCL12/SDF-1 alpha .

gene symbol :

CXCL13

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Chemotaxis Induced by CXCL13/BLC/BCA-1 and Neutralization by Mouse CXCL13/BLC/BCA-1 Antibody.

accessionNumbers :

O55038

applications :

Luminex Development,Neutralization,Direct ELISA,Cell Selection,Immunohistochemistry-Frozen,ELISA Capture (Matched Antibody Pair)

USD :

489 USD

alt names :

ANGIE, ANGIE2, B cell-attracting chemokine 1, B lymphocyte chemoattractant, BCA1, BCA-1, BCA1B-cell chemoattractant, BCA-1CXC chemokine BLC, B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1), BLC, BLCSmall-inducible cytokine B13, BLR1L, B-lymphocyte chemoattractant, chemokine (C-X-C motif) ligand 13, chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant), C-X-C motif chemokine 13, SCYB13, SCYB13B-cell-attracting chemokine 1, small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cellchemoattractant)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage