product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse gp130 Antibody
catalog :
MAB4682-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
459 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
125605
reactivity :
human, mouse
application :
ELISA, neutralization, flow cytometry
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse
Weinstock A, RAHMAN K, Yaacov O, Nishi H, Menon P, Nikain C, et al. Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis. elife. 2021;10: pubmed publisher
Barrett T, Schlegel M, Zhou F, Gorenchtein M, Bolstorff J, Moore K, et al. Platelet regulation of myeloid suppressor of cytokine signaling 3 accelerates atherosclerosis. Sci Transl Med. 2019;11: pubmed publisher
Dixit A, Bottek J, Beerlage A, Schuettpelz J, Thiebes S, Brenzel A, et al. Frontline Science: Proliferation of Ly6C+ monocytes during urinary tract infections is regulated by IL-6 trans-signaling. J Leukoc Biol. 2017;: pubmed publisher
Wang X, Miller E, Goswami M, Zhang P, Ronning K, Karlen S, et al. Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130. J Neuroinflammation. 2017;14:121 pubmed publisher
Morrison C, Mancini S, Cipollone J, Kappelhoff R, Roskelley C, Overall C. Microarray and proteomic analysis of breast cancer cell and osteoblast co-cultures: role of osteoblast matrix metalloproteinase (MMP)-13 in bone metastasis. J Biol Chem. 2011;286:34271-85 pubmed publisher
product information
master code :
MAB4682
SKU :
MAB4682-100
product name :
Mouse gp130 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Mouse gp130 Antibody from R&D Systems is a rat monoclonal antibody to gp130/CD130. This antibody reacts with mouse. The Mouse gp130 Antibody has been validated for the following applications: Neutralization,ELISA Capture (Matched Antibody Pair).
target :
gp130
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
125605
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse gp130, Gln23-Glu617, Accession # Q00560
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse gp130 ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant human gp130, recombinant mouse (rm) rmIL-6, or rmIL-6R is observed.
gene symbol :
IL6ST
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by Human IL-6 and Neutralization by Mouse gp130 Antibody.
accessionNumbers :
Q00560
applications :
Neutralization,ELISA Capture (Matched Antibody Pair)
USD :
459 USD
alt names :
CD130, CD130 antigen, CDw130, DKFZp564F053, gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB, IL-6R-beta, IL6ST, interleukin 6 signal transducer (gp130, oncostatin M receptor), interleukin receptor beta chain, interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, membrane glycoprotein gp130, Oncostatin-M receptor subunit alpha
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.