Mouse gp130 Antibody | R&D Systems MAB4681 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse gp130 Antibody

catalog :

MAB4681

quantity :

100 ug (also 25 ug)

price :

449 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

125623

reactivity :

mouse, rat

application :

western blot, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 10

Reference
Lainez N, Coss D. Leukemia Inhibitory Factor Represses GnRH Gene Expression via cFOS during Inflammation in Male Mice. Neuroendocrinology. 2019;108:291-307 pubmed publisher
Wilkinson A, Gartlan K, Kelly G, Samson L, Olver S, Avery J, et al. Granulocytes Are Unresponsive to IL-6 Due to an Absence of gp130. J Immunol. 2018;200:3547-3555 pubmed publisher
Chehboun S, Labrecque Carbonneau J, Pasquin S, Meliani Y, Meddah B, Ferlin W, et al. Epstein-Barr virus-induced gene 3 (EBI3) can mediate IL-6 trans-signaling. J Biol Chem. 2017;292:6644-6656 pubmed publisher
Li C, Bi Y, Li Y, Yang H, Yu Q, Wang J, et al. Dendritic cell MST1 inhibits Th17 differentiation. Nat Commun. 2017;8:14275 pubmed publisher
Echevarria F, Rickman A, Sappington R. Interleukin-6: A Constitutive Modulator of Glycoprotein 130, Neuroinflammatory and Cell Survival Signaling in Retina. J Clin Cell Immunol. 2016;7: pubmed
Echevarria F, Walker C, Abella S, Won M, Sappington R. Stressor-dependent Alterations in Glycoprotein 130: Implications for Glial Cell Reactivity, Cytokine Signaling and Ganglion Cell Health in Glaucoma. J Clin Exp Ophthalmol. 2013;4: pubmed
Le Goff B, Singbrant S, Tonkin B, Martin T, Romas E, Sims N, et al. Oncostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts. Cytokine. 2014;68:101-9 pubmed publisher
Bailey C, Huang I, Kam C, Farzan M. Ifitm3 limits the severity of acute influenza in mice. PLoS Pathog. 2012;8:e1002909 pubmed publisher
Matsumoto S, Hara T, Mitsuyama K, Yamamoto M, Tsuruta O, Sata M, et al. Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model. J Immunol. 2010;184:1543-51 pubmed publisher
Damon D. TH and NPY in sympathetic neurovascular cultures: role of LIF and NT-3. Am J Physiol Cell Physiol. 2008;294:C306-12 pubmed

product information

master code :

MAB4681

SKU :

MAB4681

product name :

Mouse gp130 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse gp130 Antibody from R&D Systems is a rat monoclonal antibody to gp130/CD130. This antibody reacts with mouse,rat. The Mouse gp130 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready.

target :

gp130

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

125623

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse gp130, Gln23-Glu617 (predicted), Accession # Q6PDI9

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse,Rat

specificity :

Detects mouse gp130 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human gp130 is observed.

gene symbol :

IL6ST

top caption :

Detection of gp130 antibody in Mouse Splenocytes antibody by Flow Cytometry.

accessionNumbers :

Q6PDI9

applications :

Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready

USD :

449 USD

alt names :

CD130, CD130 antigen, CDw130, DKFZp564F053, gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB, IL-6R-beta, IL6ST, interleukin 6 signal transducer (gp130, oncostatin M receptor), interleukin receptor beta chain, interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, membrane glycoprotein gp130, Oncostatin-M receptor subunit alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage