product summary
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company name :
R&D Systems
product type :
antibody
product name :
CXCL10/IP-10/CRG-2 Antibody
catalog :
MAB466-100
quantity :
100 ug (also 500 ug, 25 ug)
price :
453 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
134013
reactivity :
mouse
application :
western blot, ELISA, neutralization
more info or order :
R&D Systems product webpage
citations: 12
Reference
Peng C, Tu G, Wang J, Wang Y, Wu P, Yu L, et al. MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10. Cell Death Dis. 2023;14:155 pubmed publisher
Hu S, Gao Y, Gao R, Wang Y, Qu Y, Yang J, et al. The selective STING inhibitor H-151 preserves myocardial function and ameliorates cardiac fibrosis in murine myocardial infarction. Int Immunopharmacol. 2022;107:108658 pubmed publisher
Mawhin M, Bright R, Fourre J, Vloumidi E, Tomlinson J, Sardini A, et al. Chronic kidney disease mediates cardiac dysfunction associated with increased resident cardiac macrophages. BMC Nephrol. 2022;23:47 pubmed publisher
Mursalin M, Coburn P, Miller F, Livingston E, Astley R, Callegan M. C-X-C Chemokines Influence Intraocular Inflammation During Bacillus Endophthalmitis. Invest Ophthalmol Vis Sci. 2021;62:14 pubmed publisher
Zhang Q, Li J, Jiang K, Wang R, Ge J, Yang H, et al. CDK4/6 inhibition promotes immune infiltration in ovarian cancer and synergizes with PD-1 blockade in a B cell-dependent manner. Theranostics. 2020;10:10619-10633 pubmed publisher
Pang Z, Raudonis R, McCormick C, Cheng Z. Early Growth Response 1 Deficiency Protects the Host against Pseudomonas aeruginosa Lung Infection. Infect Immun. 2019;88: pubmed publisher
William M, Leroux L, Chaparro V, Graber T, Alain T, Jaramillo M. Translational repression of Ccl5 and Cxcl10 by 4E-BP1 and 4E-BP2 restrains the ability of mouse macrophages to induce migration of activated T cells. Eur J Immunol. 2019;49:1200-1212 pubmed publisher
Verma A, Waghmare T, Jachak G, Philkhana S, Reddy D, Basu A. Nitrosporeusine analogue ameliorates Chandipura virus induced inflammatory response in CNS via NFκb inactivation in microglia. PLoS Negl Trop Dis. 2018;12:e0006648 pubmed publisher
Lv R, Zhao J, Lei M, Xiao D, Yu Y, Xie J. IL-33 Attenuates Sepsis by Inhibiting IL-17 Receptor Signaling through Upregulation of SOCS3. Cell Physiol Biochem. 2017;42:1961-1972 pubmed publisher
Ioannidis L, Nie C, Ly A, Ryg Cornejo V, Chiu C, Hansen D. Monocyte- and Neutrophil-Derived CXCL10 Impairs Efficient Control of Blood-Stage Malaria Infection and Promotes Severe Disease. J Immunol. 2016;196:1227-38 pubmed publisher
Barreira da Silva R, Laird M, Yatim N, Fiette L, Ingersoll M, Albert M. Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy. Nat Immunol. 2015;16:850-8 pubmed publisher
Umemura N, Saio M, Suwa T, Kitoh Y, Bai J, Nonaka K, et al. Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics. J Leukoc Biol. 2008;83:1136-44 pubmed publisher
image
image 1 :
R&D Systems MAB466-100 image 1
Chemotaxis Induced by CXCL10/CRG-2 and Neutralization by Mouse CXCL10/CRG-2 Antibody.
product information
brand :
R&D Systems
master code :
MAB466
SKU :
MAB466-100
product name :
CXCL10/IP-10/CRG-2 Antibody
description :
The Mouse CXCL10/IP-10/CRG-2 Antibody from R&D Systems is a rat monoclonal antibody to CXCL10/IP-10/CRG-2. This antibody reacts with mouse. The Mouse CXCL10/IP-10/CRG-2 Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).
target :
CXCL10/IP-10/CRG-2
category :
Primary Antibodies
sizes available :
100 ug (also 500 ug, 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
134013
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse CXCL10/IP-10/CRG-2, Ile22-Pro98, Accession # P17515
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CXCL10/IP-10/CRG-2 in ELISAs and Western blots
gene symbol :
Cxcl10
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P17515
applications :
Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)
USD :
453 USD
alt names :
C7, chemokine (C-X-C motif) ligand 10, crg-2, CRG2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.