Human/Mouse Sonic Hedgehog N-Terminus Antibody | R&D Systems MAB464 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse Sonic Hedgehog N-Terminus Antibody

catalog :

MAB464

quantity :

500 ug (also 25 ug)

price :

569 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

171001

reactivity :

human, mouse, rat

application :

western blot

more info or order :

R&D Systems product webpage

citations: 4

Reference
Orzechowska Licari E, Bialkowska A, Yang V. Sonic Hedgehog and WNT Signaling Regulate a Positive Feedback Loop Between Intestinal Epithelial and Stromal Cells to Promote Epithelial Regeneration. Cell Mol Gastroenterol Hepatol. 2023;16:607-642 pubmed publisher
Maity G, Mehta S, Haque I, Dhar K, Sarkar S, Banerjee S, et al. Pancreatic tumor cell secreted CCN1/Cyr61 promotes endothelial cell migration and aberrant neovascularization. Sci Rep. 2014;4:4995 pubmed publisher
Hashimoto M, Ishii K, Nakamura Y, Watabe K, Kohsaka S, Akazawa C. Neuroprotective effect of sonic hedgehog up-regulated in Schwann cells following sciatic nerve injury. J Neurochem. 2008;107:918-27 pubmed publisher
Bänziger C, Soldini D, Schütt C, Zipperlen P, Hausmann G, Basler K. Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell. 2006;125:509-22 pubmed

product information

master code :

MAB464

SKU :

MAB464

product name :

Human/Mouse Sonic Hedgehog N-Terminus Antibody

unit size :

500 ug (also 25 ug)

description :

The Human/Mouse Sonic Hedgehog N-Terminus Antibody from R&D Systems is a rat monoclonal antibody to Sonic Hedgehog/Shh. This antibody reacts with human,mouse,rat. The Human/Mouse Sonic Hedgehog N-Terminus Antibody has been validated for the following applications: Western Blot.

target :

Sonic Hedgehog/Shh

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

171001

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse Sonic Hedgehog, Cys25-Gly198 (Lys122Arg), Accession # Q62226

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects the N-terminal peptide of human (amino acids 24-197) and mouse (amino acids 25-198) Shh in direct ELISAs and Western blots. Shows 50-100% cross-reactivity with the N-terminal peptides of recombinant mouse (rm) Dhh (amino acids 23-198) and rmIhh (amino acids 66-240) and no cross-reactivity with the C-terminal peptides from rmShh (amino acids 199-437), rmDhh (amino acids 199-396), or rmIhh (amino acids 241-449).

gene symbol :

SHH

top caption :

Detection of Human and Mouse Sonic Hedgehog/Shh antibody by Western Blot.

accessionNumbers :

Q62226

applications :

Western Blot

USD :

569 USD

alt names :

HHG1, HHG-1, HLP3, HPE3, MCOPCB5, MCOPCB5sonic hedgehog (Drosophila) homolog, Shh, ShhNC, SMMCI, SMMCIsonic hedgehog homolog (Drosophila), sonic hedgehog, sonic hedgehog homolog, sonic hedgehog protein, TPT, TPTPS

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage