product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse Sonic Hedgehog N-Terminus Antibody
catalog :
MAB464
quantity :
500 ug (also 25 ug)
price :
569 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
171001
reactivity :
human, mouse, rat
application :
western blot
more info or order :
citations: 4
Reference
Orzechowska Licari E, Bialkowska A, Yang V. Sonic Hedgehog and WNT Signaling Regulate a Positive Feedback Loop Between Intestinal Epithelial and Stromal Cells to Promote Epithelial Regeneration. Cell Mol Gastroenterol Hepatol. 2023;16:607-642 pubmed publisher
Maity G, Mehta S, Haque I, Dhar K, Sarkar S, Banerjee S, et al. Pancreatic tumor cell secreted CCN1/Cyr61 promotes endothelial cell migration and aberrant neovascularization. Sci Rep. 2014;4:4995 pubmed publisher
Hashimoto M, Ishii K, Nakamura Y, Watabe K, Kohsaka S, Akazawa C. Neuroprotective effect of sonic hedgehog up-regulated in Schwann cells following sciatic nerve injury. J Neurochem. 2008;107:918-27 pubmed publisher
Bänziger C, Soldini D, Schütt C, Zipperlen P, Hausmann G, Basler K. Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell. 2006;125:509-22 pubmed
product information
master code :
MAB464
SKU :
MAB464
product name :
Human/Mouse Sonic Hedgehog N-Terminus Antibody
unit size :
500 ug (also 25 ug)
description :
The Human/Mouse Sonic Hedgehog N-Terminus Antibody from R&D Systems is a rat monoclonal antibody to Sonic Hedgehog/Shh. This antibody reacts with human,mouse,rat. The Human/Mouse Sonic Hedgehog N-Terminus Antibody has been validated for the following applications: Western Blot.
target :
Sonic Hedgehog/Shh
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
171001
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse Sonic Hedgehog, Cys25-Gly198 (Lys122Arg), Accession # Q62226
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects the N-terminal peptide of human (amino acids 24-197) and mouse (amino acids 25-198) Shh in direct ELISAs and Western blots. Shows 50-100% cross-reactivity with the N-terminal peptides of recombinant mouse (rm) Dhh (amino acids 23-198) and rmIhh (amino acids 66-240) and no cross-reactivity with the C-terminal peptides from rmShh (amino acids 199-437), rmDhh (amino acids 199-396), or rmIhh (amino acids 241-449).
gene symbol :
SHH
top caption :
Detection of Human and Mouse Sonic Hedgehog/Shh antibody by Western Blot.
accessionNumbers :
Q62226
applications :
Western Blot
USD :
569 USD
alt names :
HHG1, HHG-1, HLP3, HPE3, MCOPCB5, MCOPCB5sonic hedgehog (Drosophila) homolog, Shh, ShhNC, SMMCI, SMMCIsonic hedgehog homolog (Drosophila), sonic hedgehog, sonic hedgehog homolog, sonic hedgehog protein, TPT, TPTPS
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.