product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CCL21/6Ckine Antibody
catalog :
MAB457-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
59106
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section, blocking or activating experiments
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; mouse; ; fig 11c
Mao F, Lv Y, Hao C, Teng Y, Liu Y, Cheng P, et al. Helicobacter pylori-Induced Rev-erbα Fosters Gastric Bacteria Colonization by Impairing Host Innate and Adaptive Defense. Cell Mol Gastroenterol Hepatol. 2021;12:395-425 pubmed publisher
Artusa P, Nguyen Yamamoto L, Barbier C, Valbon S, Aghazadeh Habashi Y, Djambazian H, et al. Skewed epithelial cell differentiation and premature aging of the thymus in the absence of vitamin D signaling. Sci Adv. 2024;10:eadm9582 pubmed publisher
Li L, Shirkey M, Zhang T, Xiong Y, Piao W, Saxena V, et al. The lymph node stromal laminin α5 shapes alloimmunity. J Clin Invest. 2020;130:2602-2619 pubmed publisher
Weitman E, Aschen S, Farias Eisner G, Albano N, Cuzzone D, Ghanta S, et al. Obesity impairs lymphatic fluid transport and dendritic cell migration to lymph nodes. PLoS ONE. 2013;8:e70703 pubmed publisher
Liu C, Saito F, Liu Z, Lei Y, Uehara S, Love P, et al. Coordination between CCR7- and CCR9-mediated chemokine signals in prevascular fetal thymus colonization. Blood. 2006;108:2531-9 pubmed
Misslitz A, Pabst O, Hintzen G, Ohl L, Kremmer E, Petrie H, et al. Thymic T cell development and progenitor localization depend on CCR7. J Exp Med. 2004;200:481-91 pubmed
Tolba K, Bowers W, Muller J, Housekneckt V, Giuliano R, Federoff H, et al. Herpes simplex virus (HSV) amplicon-mediated codelivery of secondary lymphoid tissue chemokine and CD40L results in augmented antitumor activity. Cancer Res. 2002;62:6545-51 pubmed
Ato M, Stager S, Engwerda C, Kaye P. Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis. Nat Immunol. 2002;3:1185-91 pubmed
product information
master code :
MAB457
SKU :
MAB457-100
product name :
Mouse CCL21/6Ckine Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Mouse CCL21/6Ckine Antibody from R&D Systems is a rat monoclonal antibody to CCL21/6Ckine. This antibody reacts with human,mouse. The Mouse CCL21/6Ckine Antibody has been validated for the following applications: Flow Cytometry,ELISA Development,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,Western Blot,ELISA Capture (Matched Antibody Pair),Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
CCL21/6Ckine
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
59106
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse CCL21/6Ckine, Ser24-Gly133, Accession # P84444
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects mouse CCL21/6Ckine in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) 6Ckine, rhMIP-1 alpha , rhMIP-1▀, recombinant mouse (rm) MIP-1 alpha , rmMIP-1▀, rhMIP-1 delta , rmMIP-1 gamma , rmMIP-2, rhMIP-3 alpha , rmMIP-3 alpha , rhMIP-3▀, rmMIP-3▀, rhTeck, or rmTeck.
gene symbol :
Ccl21a
top caption :
CCL21/6Ckine antibody in Mouse Thymus by Immunohistochemistry (IHC-Fr).
accessionNumbers :
P84444
applications :
Flow Cytometry,ELISA Development,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,Western Blot,ELISA Capture (Matched Antibody Pair),Intracellular Staining by Flow Cytometry,CyTOF-ready
USD :
469 USD
alt names :
6Ckine, 6CkineSmall-inducible cytokine A21, Beta-chemokine exodus-2, chemokine (C-C motif) ligand 21, CKb9, exodus-2, member 21, SCYA21, SCYA21MGC34555, secondary lymphoid tissue chemokine, SLC, SLCSecondary lymphoid-tissue chemokine, TCA-4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.