product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CXCL1/GRO alpha /KC/CINC-1 Antibody
catalog :
MAB4531-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
429 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
124014
reactivity :
human
application :
western blot, immunohistochemistry, neutralization
more info or order :
citations: 8
Reference
Logue S, McGrath E, Cleary P, Greene S, Mnich K, Almanza A, et al. Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy. Nat Commun. 2018;9:3267 pubmed publisher
Zhang H, Neuhöfer P, Song L, Rabe B, Lesina M, Kurkowski M, et al. IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality. J Clin Invest. 2013;123:1019-31 pubmed publisher
Aeffner F, Davis I. Respiratory syncytial virus reverses airway hyperresponsiveness to methacholine in ovalbumin-sensitized mice. PLoS ONE. 2012;7:e46660 pubmed publisher
Proebstl D, Voisin M, Woodfin A, Whiteford J, D Acquisto F, Jones G, et al. Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. J Exp Med. 2012;209:1219-34 pubmed publisher
Kim J, Natarajan S, Vaickus L, Bouchard J, Beal D, Cruikshank W, et al. Diesel exhaust particulates exacerbate asthma-like inflammation by increasing CXC chemokines. Am J Pathol. 2011;179:2730-9 pubmed publisher
Breslow J, Meissler J, Hartzell R, Spence P, Truant A, Gaughan J, et al. Innate immune responses to systemic Acinetobacter baumannii infection in mice: neutrophils, but not interleukin-17, mediate host resistance. Infect Immun. 2011;79:3317-27 pubmed publisher
Zhao C, Sardella A, Chun J, Poubelle P, Fernandes M, Bourgoin S. TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines. J Lipid Res. 2011;52:1307-18 pubmed publisher
Traylor Z, Yu E, Davis I. Respiratory syncytial virus induces airway insensitivity to beta-agonists in BALB/c mice. Am J Physiol Lung Cell Mol Physiol. 2010;298:L437-45 pubmed publisher
product information
master code :
MAB4531
SKU :
MAB4531-100
product name :
Mouse CXCL1/GRO alpha /KC/CINC-1 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Mouse CXCL1/GRO alpha /KC/CINC-1 Antibody from R&D Systems is a rat monoclonal antibody to CXCL1/GRO alpha/KC/CINC-1. This antibody reacts with mouse. The Mouse CXCL1/GRO alpha /KC/CINC-1 Antibody has been validated for the following applications: Neutralization,Immunohistochemistry,Western Blot.
target :
CXCL1/GRO alpha/KC/CINC-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
124014
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse CXCL1/GRO alpha /KC/CINC-1, Arg20-Lys96, Accession # P12850
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CXCL1 in Western blots. Does not cross-react with recombinant human CXCL2, 3, 5, 6, 8, 9, 10, 11, 12/SDF-1 alpha , 12/SDF-1▀, 13, recombinant mouse CXCL2, 6, 9, 10, 11, 12/SDF-1 alpha , 13, 15, recombinant rat (rr) CXCL2, rrCXCL3/CINC-2 alpha , rrCXCL3/CINC-2▀, rrCXCL5, or recombinant porcine CXCL8.
gene symbol :
Cxcl1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Chemotaxis Induced by CXCL1/KC and Neutralization by Mouse CXCL1/KC Antibody.
accessionNumbers :
P12850
applications :
Neutralization,Immunohistochemistry,Western Blot
USD :
429 USD
alt names :
CINC1, CINC-1, FSP, GRO alpha, GRO1, GROa, KC, MGSA, MGSA-a, MGSA-alpha, NAP-3, SCYB1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.