product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Phospho-FAK (Y397) Antibody
catalog :
MAB4528
quantity :
100 ug (also 25 ug)
price :
449 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
820755
reactivity :
human
application :
western blot
more info or order :
citations: 5
Reference
Wantoch von Rekowski K, König P, Henze S, Schlesinger M, Zawierucha P, Januchowski R, et al. Insight into Cisplatin-Resistance Signaling of W1 Ovarian Cancer Cells Emerges mTOR and HSP27 as Targets for Sensitization Strategies. Int J Mol Sci. 2020;21: pubmed publisher
Tsygankova O, Keen J. A unique role for clathrin light chain A in cell spreading and migration. J Cell Sci. 2019;132: pubmed publisher
Jeong K, Murphy J, Rodriguez Y, Kim J, Ahn E, Lim S. FAK inhibition reduces metastasis of α4 integrin-expressing melanoma to lymph nodes by targeting lymphatic VCAM-1 expression. Biochem Biophys Res Commun. 2019;509:1034-1040 pubmed publisher
Pak J, Bashir Q, Kim I, Hong S, Maeng S, Bahk Y, et al. Clonorchis sinensis excretory-secretory products promote the migration and invasion of cholangiocarcinoma cells by activating the integrin ?4-FAK/Src signaling pathway. Mol Biochem Parasitol. 2017;214:1-9 pubmed publisher
Ye F, Zhou F, Nithianantham S, Chandran B, Yu X, Weinberg A, et al. Kaposi's sarcoma-associated herpesvirus induces rapid release of angiopoietin-2 from endothelial cells. J Virol. 2013;87:6326-35 pubmed publisher
product information
master code :
MAB4528
SKU :
MAB4528
product name :
Human Phospho-FAK (Y397) Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Phospho-FAK (Y397) Antibody from R&D Systems is a rat monoclonal antibody to FAK. This antibody reacts with human. The Human Phospho-FAK (Y397) Antibody has been validated for the following applications: Western Blot.
target :
FAK
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
820755
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Phosphopeptide containing the human FAK Y397 site, Accession # Q05397
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human FAK when phosphorylated at Y397.
gene symbol :
PTK2
top caption :
Detection of Human Phospho-FAK (Y397) antibody by Western Blot.
accessionNumbers :
Q05397
applications :
Western Blot
USD :
449 USD
alt names :
EC 2.7.10, FADK 1, FADK1, FADKFAK-related non-kinase polypeptide, FAK1FRNK, FAKEC 2.7.10.2, focal adhesion kinase 1, pp125FAK, Protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.