product summary
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company name :
R&D Systems
product type :
antibody
product name :
CXCL2/GRO beta/MIP-2/CINC-3 Antibody
catalog :
MAB452-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
389 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
40605
reactivity :
human, mouse
application :
western blot, ELISA, neutralization
more info or order :
citations: 41
Reference
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Finsterbusch M, Hall P, Li A, Devi S, Westhorpe C, Kitching A, et al. Patrolling monocytes promote intravascular neutrophil activation and glomerular injury in the acutely inflamed glomerulus. Proc Natl Acad Sci U S A. 2016;113:E5172-81 pubmed publisher
Denney L, Byrne A, Shea T, Buckley J, Pease J, Herledan G, et al. Pulmonary Epithelial Cell-Derived Cytokine TGF-β1 Is a Critical Cofactor for Enhanced Innate Lymphoid Cell Function. Immunity. 2015;43:945-58 pubmed publisher
Lin Y, Yet S, Hsu Y, Wang G, Hung S. Mesenchymal Stem Cells Ameliorate Atherosclerotic Lesions via Restoring Endothelial Function. Stem Cells Transl Med. 2015;4:44-55 pubmed publisher
Kowalewska P, Patrick A, Fox Robichaud A. Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation. PLoS ONE. 2014;9:e104537 pubmed publisher
Raghuwanshi S, Smith N, Rivers E, Thomas A, Sutton N, Hu Y, et al. G protein-coupled receptor kinase 6 deficiency promotes angiogenesis, tumor progression, and metastasis. J Immunol. 2013;190:5329-36 pubmed publisher
Junkins R, MacNeil A, Wu Z, McCormick C, Lin T. Regulator of calcineurin 1 suppresses inflammation during respiratory tract infections. J Immunol. 2013;190:5178-86 pubmed publisher
Roy M, Richard J, Dumas A, Vallières L. CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis. J Neuroinflammation. 2012;9:18 pubmed publisher
Cheung R, Shen F, Phillips J, McGeachy M, Cua D, Heyworth P, et al. Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice. J Clin Invest. 2011;121:4446-61 pubmed publisher
Kim J, Natarajan S, Vaickus L, Bouchard J, Beal D, Cruikshank W, et al. Diesel exhaust particulates exacerbate asthma-like inflammation by increasing CXC chemokines. Am J Pathol. 2011;179:2730-9 pubmed publisher
Zhao C, Sardella A, Chun J, Poubelle P, Fernandes M, Bourgoin S. TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines. J Lipid Res. 2011;52:1307-18 pubmed publisher
Summers S, van der Veen B, O Sullivan K, Gan P, Ooi J, Heeringa P, et al. Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis. Kidney Int. 2010;78:1263-74 pubmed publisher
Chou R, Kim N, Sadik C, Seung E, Lan Y, Byrne M, et al. Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis. Immunity. 2010;33:266-78 pubmed publisher
Massena S, Christoffersson G, Hjertström E, Zcharia E, Vlodavsky I, Ausmees N, et al. A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils. Blood. 2010;116:1924-31 pubmed publisher
Horvat J, Starkey M, Kim R, Beagley K, Preston J, Gibson P, et al. Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease. J Immunol. 2010;184:4159-69 pubmed publisher
Nold Petry C, Nold M, Nielsen J, Bustamante A, Zepp J, Storm K, et al. Increased cytokine production in interleukin-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling. J Biol Chem. 2009;284:25900-11 pubmed publisher
Wieland C, van der Windt G, Florquin S, McKenzie A, van der Poll T. ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis. Microbes Infect. 2009;11:524-30 pubmed publisher
Kimura K, Nagaki M, Kakimi K, Saio M, Saeki T, Okuda Y, et al. Critical role of CD44 in hepatotoxin-mediated liver injury. J Hepatol. 2008;48:952-61 pubmed publisher
Wieland C, van der Windt G, Wiersinga W, Florquin S, van der Poll T. CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis. Immunology. 2008;125:272-9 pubmed publisher
De Filippo K, Henderson R, Laschinger M, Hogg N. Neutrophil chemokines KC and macrophage-inflammatory protein-2 are newly synthesized by tissue macrophages using distinct TLR signaling pathways. J Immunol. 2008;180:4308-15 pubmed
Scortegagna M, Cataisson C, Martin R, Hicklin D, Schreiber R, Yuspa S, et al. HIF-1alpha regulates epithelial inflammation by cell autonomous NFkappaB activation and paracrine stromal remodeling. Blood. 2008;111:3343-54 pubmed publisher
Wengner A, Pitchford S, Furze R, Rankin S. The coordinated action of G-CSF and ELR + CXC chemokines in neutrophil mobilization during acute inflammation. Blood. 2008;111:42-9 pubmed
Halder R, Aguilera C, Maricic I, Kumar V. Type II NKT cell-mediated anergy induction in type I NKT cells prevents inflammatory liver disease. J Clin Invest. 2007;117:2302-12 pubmed
Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, et al. Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis. J Immunol. 2006;177:8650-7 pubmed
Hajjar A, Harvey M, Shaffer S, Goodlett D, Sjostedt A, Edebro H, et al. Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors. Infect Immun. 2006;74:6730-8 pubmed
Ramos C, Fernandes K, Canetti C, Teixeira M, Silva J, Cunha F. Neutrophil recruitment in immunized mice depends on MIP-2 inducing the sequential release of MIP-1alpha, TNF-alpha and LTB(4). Eur J Immunol. 2006;36:2025-34 pubmed
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Dajee M, Muchamuel T, Schryver B, Oo A, Alleman Sposeto J, De Vry C, et al. Blockade of experimental atopic dermatitis via topical NF-kappaB decoy oligonucleotide. J Invest Dermatol. 2006;126:1792-803 pubmed
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Knott P, Gater P, Dunford P, Fuentes M, Bertrand C. Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation. J Immunol. 2001;166:1233-40 pubmed
image
image 1 :
R&D Systems MAB452-100 image 1
Chemotaxis Induced by CXCL2/MIP-2 and Neutralization by Mouse CXCL2/MIP-2 Antibody.
product information
brand :
R&D Systems
master code :
MAB452
SKU :
MAB452-100
product name :
CXCL2/GRO beta/MIP-2/CINC-3 Antibody
description :
The CXCL2/GRO beta/MIP-2/CINC-3 Antibody from MAB452-100 is a mab452 antibody to . The CXCL2/GRO beta/MIP-2/CINC-3 Antibody has been validated for the following applications: P10889.
target :
CXCL2/GRO beta/MIP-2/CINC-3
category :
Primary Antibodies
unit sizes :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
40605
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse CXCL2/GRO beta/MIP-2/CINC-3, Ala28-Asn100, Accession # P10889
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CXCL2 in ELISAs and Western blots
gene symbol :
CXCL2
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P10889
applications :
Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)
USD :
389 USD
alt names :
chemokine (C-X-C motif) ligand 2, CINC-2a, CINC3, CINC-3, C-X-C Motif Chemokine 2, GRO beta, GRO2, GRO2 oncogene, GROb, Gro-beta, Growth-regulated protein beta, Macrophage inflammatory protein 2-alpha, melanoma growth stimulatory activity beta, MGSA beta, MGSA-b, MGSA-beta, MIP2, MIP-2, MIP-2a, MIP2A, MIP2-alpha, SCYB2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.