product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Neutrophil Elastase/ELA2 Antibody
catalog :
MAB4517
quantity :
100 ug (also 25 ug)
price :
459 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
887105
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 5
Reference
Ostermann L, Seeliger B, David S, Flasche C, Maus R, Reinboth M, et al. S100A9 is indispensable for survival of pneumococcal pneumonia in mice. PLoS Pathog. 2023;19:e1011493 pubmed publisher
Ye D, Yao J, Du W, Chen C, Yang Y, Yan K, et al. Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/Neutrophil Elastase Signaling in Mice. Cell Mol Gastroenterol Hepatol. 2022;14:587-607 pubmed publisher
Margaroli C, Madison M, Viera L, Russell D, Gaggar A, Genschmer K, et al. An in vivo model for extracellular vesicle-induced emphysema. JCI Insight. 2022;7: pubmed publisher
Weckbach L, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, et al. Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. J Exp Med. 2019;216:350-368 pubmed publisher
Pires S, Parker D. IL-1β activation in response to Staphylococcus aureus lung infection requires inflammasome-dependent and independent mechanisms. Eur J Immunol. 2018;48:1707-1716 pubmed publisher
product information
master code :
MAB4517
SKU :
MAB4517
product name :
Mouse Neutrophil Elastase/ELA2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse Neutrophil Elastase/ELA2 Antibody from R&D Systems is a rat monoclonal antibody to Neutrophil Elastase/ELA2. This antibody reacts with human,mouse. The Mouse Neutrophil Elastase/ELA2 Antibody has been validated for the following applications: Immunocytochemistry/ Immunofluorescence,Flow Cytometry,Western Blot,Immunohistochemistry,Immunocytochemistry.
target :
Neutrophil Elastase/ELA2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
887105
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Neutrophil Elastase/ELA2, Met1-Arg260, Accession # Q3UP87
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse Neutrophil Elastase/ELA2 in direct ELISAs and Western blots.
gene symbol :
ELANE
top caption :
Detection of Mouse Neutrophil Elastase/ELA2 antibody by Western Blot.
accessionNumbers :
Q3UP87
applications :
Flow Cytometry,Western Blot,Immunohistochemistry,Immunocytochemistry
USD :
459 USD
alt names :
Bone marrow serine protease, EC 3.4.21, EC 3.4.21.37, ELA2, ELA2granulocyte-derived elastase, ELANE, elastase 2, neutrophil, elastase, neutrophil expressed, Elastase-2, GE, HLEelastase-2, HNE, Human leukocyte elastase, Leukocyte Elastase, medullasin, NE, neutrophil elastase, PMN elastase, PMN-E, polymorphonuclear elastase, SCN1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.