Mouse IL-17RA/IL-17R Antibody | R&D Systems MAB4481 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-17RA/IL-17R Antibody

catalog :

MAB4481

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

657603

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 10

Reference
Li T, Hu L, Qin C, Li Y, Song Z, Jiao Y, et al. Annexin 1 Reduces Dermatitis-Induced Itch and Cholestatic Itch through Inhibiting Neuroinflammation and Iron Overload in the Spinal Dorsal Horn of Mice. Brain Sci. 2024;14: pubmed publisher
Lv X, Lv S, Wang G, Chang Y, Cai Y, Liu H, et al. Glia-derived adenosine in the ventral hippocampus drives pain-related anxiodepression in a mouse model resembling trigeminal neuralgia. Brain Behav Immun. 2024;117:224-241 pubmed publisher
Knizkova D, Pribikova M, Draberova H, Semberova T, Trivic T, Synackova A, et al. CMTM4 is a subunit of the IL-17 receptor and mediates autoimmune pathology. Nat Immunol. 2022;23:1644-1652 pubmed publisher
Yoshida T, Das N, Carpenter A, Izadpanah R, Kumar S, Gautam S, et al. Minocycline reverses IL-17A/TRAF3IP2-mediated p38 MAPK/NF-κB/iNOS/NO-dependent cardiomyocyte contractile depression and death. Cell Signal. 2020;73:109690 pubmed publisher
Saleh M, Frisbee A, Leslie J, Buonomo E, Cowardin C, Ma J, et al. Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection. Cell Host Microbe. 2019;25:756-765.e5 pubmed publisher
Yan J, Li Y, Yang H, Zhang L, Yang B, Wang M, et al. Interleukin-17A participates in podocyte injury by inducing IL-1Î² secretion through ROS-NLRP3 inflammasome-caspase-1 pathway. Scand J Immunol. 2018;87:e12645 pubmed publisher
Akbay E, Koyama S, Liu Y, Dries R, Bufe L, Silkes M, et al. Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade. J Thorac Oncol. 2017;12:1268-1279 pubmed publisher
Qiu A, Liu Q, Wang J. Blocking IL-17A Alleviates Diabetic Retinopathy in Rodents. Cell Physiol Biochem. 2017;41:960-972 pubmed publisher
Ippagunta S, Gangwar R, Finkelstein D, Vogel P, Pelletier S, Gingras S, et al. Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function. Proc Natl Acad Sci U S A. 2016;113:E6162-E6171 pubmed
Wu S, Yu J, Liu F, Miaw S, Wu Hsieh B. Galectin-3 negatively regulates dendritic cell production of IL-23/IL-17-axis cytokines in infection by Histoplasma capsulatum. J Immunol. 2013;190:3427-37 pubmed publisher

product information

master code :

MAB4481

SKU :

MAB4481

product name :

Mouse IL-17RA/IL-17R Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse IL-17RA/IL-17R Antibody from R&D Systems is a rat monoclonal antibody to IL-17RA/IL-17R. This antibody reacts with human,mouse,rat. The Mouse IL-17RA/IL-17R Antibody has been validated for the following applications: Neutralization,In vivo assay,Flow Cytometry,Western Blot,Immunohistochemistry,CyTOF-ready.

target :

IL-17RA/IL-17R

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

657603

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse IL-17 RA/IL-17 R, Ser32-Trp322, Accession # Q60943

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse,Rat

specificity :

Detects mouse IL-17 RA/IL-17 R in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human IL-17 RA, recombinant mouse (rm) IL-17B R, rmIL-17 RD, or rmIL-17 RC is observed. In Western blots, less than 10% cross-reactivity with recombinant human (rh) IL-17 RA or rhIL-17B R is observed.

gene symbol :

IL17RA

top caption :

Detection of IL-17 RA/IL-17 R antibody in EL-4 Mouse Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q60943

applications :

In vivo assay,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,CyTOF-ready

USD :

469 USD

alt names :

CD217, CD217 antigen, Cdw217, CDw217interleukin 17 receptor, hIL-17R, IL-17 R, IL-17 RA, IL-17 receptor A, IL17RA, IL-17RAMGC10262, IL17Rinterleukin-17 receptor A, interleukin 17 receptor A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage