VEGFR2/KDR/Flk-1 Antibody | R&D Systems MAB4431-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

VEGFR2/KDR/Flk-1 Antibody

catalog :

MAB4431-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

419 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

91202

reactivity :

mouse

application :

ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 5

Reference
Rossato F, Su Y, Mackey A, Ng Y. Fibrotic Changes and Endothelial-to-Mesenchymal Transition Promoted by VEGFR2 Antagonism Alter the Therapeutic Effects of VEGFA Pathway Blockage in a Mouse Model of Choroidal Neovascularization. Cells. 2020;9: pubmed publisher
Polena H, Boudou F, Tilleul S, Dubois Colas N, Lecointe C, Rakotosamimanana N, et al. Mycobacterium tuberculosis exploits the formation of new blood vessels for its dissemination. Sci Rep. 2016;6:33162 pubmed publisher
Voron T, Colussi O, Marcheteau E, Pernot S, Nizard M, Pointet A, et al. VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors. J Exp Med. 2015;212:139-48 pubmed publisher
Nagai N, Lundh von Leithner P, Izumi Nagai K, Hosking B, Chang B, Hurd R, et al. Spontaneous CNV in a novel mutant mouse is associated with early VEGF-A-driven angiogenesis and late-stage focal edema, neural cell loss, and dysfunction. Invest Ophthalmol Vis Sci. 2014;55:3709-19 pubmed publisher
Zhang Z, Ramirez N, Yankeelov T, Li Z, Ford L, Qi Y, et al. alpha2beta1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner. Blood. 2008;111:1980-8 pubmed

image

image 1 :

VEGFR2/KDR/Flk-1 Inhibition of VEGF-dependent Cell Proliferation and Neutralization by Mouse VEGFR2/KDR/Flk-1 Antibody.

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB4431

SKU :

MAB4431-100

product name :

VEGFR2/KDR/Flk-1 Antibody

Description :

The Mouse VEGFR2/KDR/Flk-1 Antibody from R&D Systems is a rat monoclonal antibody to VEGFR2/KDR/Flk-1. This antibody reacts with mouse. The Mouse VEGFR2/KDR/Flk-1 Antibody has been validated for the following applications: Neutralization, ELISA Capture (Matched Antibody Pair).

target :

VEGFR2/KDR/Flk-1

category :

Primary Antibodies

unit size :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

91202

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse VEGFR2, Ala20-Glu762, Accession # P35918

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse VEGFR2 in Western blots.

gene symbol :

KDR

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

P35918

applications :

Neutralization, ELISA Capture (Matched Antibody Pair)

USD :

419 USD

alt names :

CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, Flk1, Flk-1, FLK1tyrosine kinase growth factor receptor, KDR, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), KRD1, Ly73, Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGF R2, VEGFR, VEGFR2, VEGFR-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage