Mouse CCL22/MDC Antibody | R&D Systems MAB4391-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse CCL22/MDC Antibody

catalog :

MAB4391-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

158132

reactivity :

human, mouse

application :

ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 6

Reference
Klarquist J, Tobin K, Farhangi Oskuei P, Henning S, Fernandez M, Dellacecca E, et al. Ccl22 Diverts T Regulatory Cells and Controls the Growth of Melanoma. Cancer Res. 2016;76:6230-6240 pubmed
Santulli Marotto S, Wheeler J, Lacy E, Boakye K, Luongo J, Wu S, et al. CCL22-specific Antibodies Reveal That Engagement of Two Distinct Binding Domains on CCL22 Is Required for CCR4-mediated Function. Monoclon Antib Immunodiagn Immunother. 2015;34:373-80 pubmed publisher
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed publisher
Kearley J, Buckland K, Mathie S, Lloyd C. Resolution of allergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathway. Am J Respir Crit Care Med. 2009;179:772-81 pubmed publisher
Kearley J, Robinson D, Lloyd C. CD4+CD25+ regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling. J Allergy Clin Immunol. 2008;122:617-24.e6 pubmed publisher
Meyer E, Wurbel M, Staton T, Pichavant M, Kan M, Savage P, et al. iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity. J Immunol. 2007;179:4661-71 pubmed

product information

master code :

MAB4391

SKU :

MAB4391-100

product name :

Mouse CCL22/MDC Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Mouse CCL22/MDC Antibody from R&D Systems is a rat monoclonal antibody to CCL22/MDC. This antibody reacts with mouse. The Mouse CCL22/MDC Antibody has been validated for the following applications: Neutralization,ELISA Development,Luminex Development,ELISA Capture (Matched Antibody Pair).

target :

CCL22/MDC

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

158132

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse CCL22/MDC, Gly25-Ser92, Accession # O88430

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse CCL22/MDC in ELISAs and Western blots. In Western blots, this antibody shows 25% cross-reactivity with recombinant viral MIP-II and no cross-reactivity with rmCCL1, 2, 3, 4, 6, 7, CCL9/10/MIP-1 gamma , 11, 12, 19, 20, 21, 22, 24, 25, 27, rhCCL1, 2, 3, 4, 5, 7, 8, 11, 13, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 28, or rrCCL20.

gene symbol :

CCL22

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Chemotaxis Induced by CCL22/MDC and Neutralization by Mouse CCL22/MDC Antibody.

accessionNumbers :

O88430

applications :

ELISA Development,Luminex Development,Neutralization,ELISA Capture (Matched Antibody Pair)

USD :

459 USD

alt names :

A-152E5.1, ABCD-1, CC chemokine STCP-1, C-C motif chemokine 22, chemokine (C-C motif) ligand 22, DC/B-CK, Macrophage-derived chemokine, MDC, MDCStimulated T-cell chemotactic protein 1, MGC34554, SCYA22MDC(1-69), small inducible cytokine A22, small inducible cytokine subfamily A (Cys-Cys), member 22, Small-inducible cytokine A22, STCP-1, stimulated T cell chemotactic protein 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage