product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CTLA-4 Antibody
catalog :
MAB434-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
479 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
63828
reactivity :
human, mouse
application :
western blot, neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 2
Reference
Inoue S, Bo L, Bian J, Unsinger J, Chang K, Hotchkiss R. Dose-dependent effect of anti-CTLA-4 on survival in sepsis. Shock. 2011;36:38-44 pubmed publisher
Kipnis J, Cardon M, Avidan H, Lewitus G, Mordechay S, Rolls A, et al. Dopamine, through the extracellular signal-regulated kinase pathway, downregulates CD4+CD25+ regulatory T-cell activity: implications for neurodegeneration. J Neurosci. 2004;24:6133-43 pubmed
product information
master code :
MAB434
SKU :
MAB434-100
product name :
Mouse CTLA-4 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Mouse CTLA-4 Antibody from R&D Systems is a rat monoclonal antibody to CTLA-4. This antibody reacts with mouse. The Mouse CTLA-4 Antibody has been validated for the following applications: Neutralization,Functional Assay,Flow Cytometry,Western Blot,CyTOF-ready.
target :
CTLA-4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
63828
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse CTLA-4, Ala36-Phe161, Accession # XP_001479180
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CTLA-4 in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant mouse (rm) CD28, recombinant human CTLA-4, rmICOS, or rmPD-1.
gene symbol :
CTLA4
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
CTLA-4 Inhibition of B7-1/CD80-induced IL-2 Secretion and Neutralization by Mouse CTLA-4 Antibody.
accessionNumbers :
XP_001479180
applications :
Functional Assay,Flow Cytometry,Western Blot,Neutralization,CyTOF-ready
USD :
479 USD
alt names :
CD, CD152, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA4, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.