TNF RI/TNFRSF1A Antibody | R&D Systems MAB430-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

TNF RI/TNFRSF1A Antibody

catalog :

MAB430-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

489 USD

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

55R170

reactivity :

mouse

application :

western blot, neutralization, immunoprecipitation, blocking or activating experiments

more info or order :

R&D Systems product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse; 5 ug/ml; fig 6c	Yu D, Li T, Delpech J, Zhu B, Kishore P, Koshi T, et al. Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits. Sci Adv. 2022;8:eabm2545 pubmed publisher
	Moujalled D, Gangatirkar P, Kauppi M, Corbin J, Lebois M, Murphy J, et al. The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis. Cell Death Dis. 2021;12:133 pubmed publisher
	Ebert G, Lopaticki S, O Neill M, Steel R, Doerflinger M, Rajasekaran P, et al. Targeting the Extrinsic Pathway of Hepatocyte Apoptosis Promotes Clearance of Plasmodium Liver Infection. Cell Rep. 2020;30:4343-4354.e4 pubmed publisher
	Shi L, Wang J, Ding N, Zhang Y, Zhu Y, Dong S, et al. Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy. Nat Commun. 2019;10:5421 pubmed publisher
	Huang H, Huang Q, Wang F, Milner R, Li L. Cerebral ischemia-induced angiogenesis is dependent on tumor necrosis factor receptor 1-mediated upregulation of Î±5Î²1 and Î±VÎ²3 integrins. J Neuroinflammation. 2016;13:227 pubmed publisher
	Wertz I, Newton K, Seshasayee D, Kusam S, Lam C, Zhang J, et al. Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Nature. 2015;528:370-5 pubmed publisher
	Goto Y, Ogawa K, Nakamura T, Hattori A, Tsujimoto M. TLR-mediated secretion of endoplasmic reticulum aminopeptidase 1 from macrophages. J Immunol. 2014;192:4443-52 pubmed publisher
	Tsai C, Chen W, Hsieh H, Chi P, Hsiao L, Yang C. TNF-? induces matrix metalloproteinase-9-dependent soluble intercellular adhesion molecule-1 release via TRAF2-mediated MAPKs and NF-?B activation in osteoblast-like MC3T3-E1 cells. J Biomed Sci. 2014;21:12 pubmed publisher
	Kudo H, Takahara T, Yata Y, Kawai K, Zhang W, Sugiyama T. Lipopolysaccharide triggered TNF-alpha-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis model. J Hepatol. 2009;51:168-75 pubmed publisher
	Saperstein S, Chen L, Oakes D, Pryhuber G, Finkelstein J. IL-1beta augments TNF-alpha-mediated inflammatory responses from lung epithelial cells. J Interferon Cytokine Res. 2009;29:273-84 pubmed publisher
	Lahat N, Rahat M, Kinarty A, Weiss Cerem L, Pinchevski S, Bitterman H. Hypoxia enhances lysosomal TNF-alpha degradation in mouse peritoneal macrophages. Am J Physiol Cell Physiol. 2008;295:C2-12 pubmed publisher
	Ojaniemi M, Liljeroos M, Harju K, Sormunen R, Vuolteenaho R, Hallman M. TLR-2 is upregulated and mobilized to the hepatocyte plasma membrane in the space of Disse and to the Kupffer cells TLR-4 dependently during acute endotoxemia in mice. Immunol Lett. 2006;102:158-68 pubmed

image

image 1 :

Cytotoxicity Induced by TNF-a and Neutralization by Mouse TNF RI/TNFRSF1A Antibody.

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB430

SKU :

MAB430-100

product name :

TNF RI/TNFRSF1A Antibody

Description :

The Mouse TNF RI/TNFRSF1A Antibody from R&D Systems is a hamster monoclonal antibody to TNF RI/TNFRSF1A. This antibody reacts with mouse. The Mouse TNF RI/TNFRSF1A Antibody has been validated for the following applications: Western Blot, Immunoprecipitation, Neutralization.

target :

TNF RI/TNFRSF1A

category :

Primary Antibodies

unit size :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

55R170

conjugate :

Unconjugated

host :

Hamster

immunogen :

Recombinant mouse TNF RI/TNFRSF1A, Extracellular domain

isotype :

IgG

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse TNF RI/TNFRSF1A in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) 4-1BB, rhCD27, rhCD30, recombinant mouse (rm) CD27, rmCD30, rhCD40, rmCD40, rhDR3, rhDR6, rmEDAR, rhFas, rmFas, rhEDAR, rhGITR, rmGITR, rhHVEM, rhLT beta R, rmLT beta R, rhNGF R, rhOPG, rmOPG, rhRANK, rmRANK, rhTAJ, rhTNF RI, rhTNF RII or rmTNF RII is observed.

gene symbol :

TNFRSF1A

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

applications :

Western Blot, Immunoprecipitation, Neutralization

USD :

489 USD

alt names :

CD120a, CD120a antigen, FPF, p55, p55-R, p60, TNFARMGC19588, TNF-R, TNF-R1, TNFR1TBP1, TNFR55, TNF-R55, TNFR60, TNFRI, TNF-RI, TNF-R-I, TNFR-I, TNFRSF1A, tumor necrosis factor binding protein 1, Tumor necrosis factor receptor 1, tumor necrosis factor receptor 1A isoform beta, tumor necrosis factor receptor superfamily member 1A, tumor necrosis factor receptor superfamily, member 1A, tumor necrosis factor receptor type 1, Tumor necrosis factor receptor type I, tumor necrosis factor-alpha receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage