Human IkB-alpha Antibody | R&D Systems MAB4299 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IkB-alpha Antibody

catalog :

MAB4299

quantity :

50 ug (also 25 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

417208

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Bernau K, Leet J, Floerke H, Bruhn E, Noll A, McDermott I, et al. Interleukin-1α Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation. Cells. 2021;10: pubmed publisher
Minden Birkenmaier B, Cherukuri K, Smith R, Radic M, Bowlin G. Manuka Honey Modulates the Inflammatory Behavior of a dHL-60 Neutrophil Model under the Cytotoxic Limit. Int J Biomater. 2019;2019:6132581 pubmed publisher
Raby A, González Mateo G, Williams A, Topley N, Fraser D, López Cabrera M, et al. Targeting Toll-like receptors with soluble Toll-like receptor 2 prevents peritoneal dialysis solution-induced fibrosis. Kidney Int. 2018;94:346-362 pubmed publisher
Tesoriere L, Attanzio A, Allegra M, Gentile C, Livrea M. Indicaxanthin inhibits NADPH oxidase (NOX)-1 activation and NF-?B-dependent release of inflammatory mediators and prevents the increase of epithelial permeability in IL-1?-exposed Caco-2 cells. Br J Nutr. 2014;111:415-23 pubmed publisher
Tesoriere L, Attanzio A, Allegra M, Gentile C, Livrea M. Phytochemical indicaxanthin suppresses 7-ketocholesterol-induced THP-1 cell apoptosis by preventing cytosolic Ca(2+) increase and oxidative stress. Br J Nutr. 2013;110:230-40 pubmed publisher
Wilhelmsen K, Mesa K, Lucero J, Xu F, Hellman J. ERK5 protein promotes, whereas MEK1 protein differentially regulates, the Toll-like receptor 2 protein-dependent activation of human endothelial cells and monocytes. J Biol Chem. 2012;287:26478-94 pubmed publisher

product information

master code :

MAB4299

SKU :

MAB4299

product name :

Human IkB-alpha Antibody

unit size :

50 ug (also 25 ug)

description :

The Human IkB-alpha Antibody from R&D Systems is a mouse monoclonal antibody to IkB-alpha. This antibody reacts with human. The Human IkB-alpha Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Simple Western,Knockout Validated.

target :

IkB-alpha

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

417208

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human IkB-alpha , Met1-Leu317, Accession # P25963

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human IkB-alpha in Western blots.

gene symbol :

NFKBIA

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human IkB-a antibody by Western Blot.

accessionNumbers :

P25963

applications :

Western Blot,Immunohistochemistry,Simple Western,Knockout Validated

USD :

359 USD

alt names :

alpha, I-kappa-B-alpha, IkappaBalphaNF-kappa-B inhibitor alpha, IKBAikB-alpha, IkBalpha, IkB-alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NFKBI, NFKBIA, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage