Mouse IL-22 R alpha 1 Antibody | R&D Systems MAB42941 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-22 R alpha 1 Antibody

catalog :

MAB42941

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

496514

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 11

Reference
Tan C, Hong G, Wang Z, Duan C, Hou L, Wu J, et al. Promoting Effect of L-Fucose on the Regeneration of Intestinal Stem Cells through AHR/IL-22 Pathway of Intestinal Lamina Propria Monocytes. Nutrients. 2022;14: pubmed publisher
Lu S, Pan H, Hsu Y, Chang K, Wu L, Chen W, et al. IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models. Nat Commun. 2020;11:4611 pubmed publisher
Aggor F, Break T, Trevejo Nuñez G, Whibley N, Coleman B, Bailey R, et al. Oral epithelial IL-22/STAT3 signaling licenses IL-17-mediated immunity to oral mucosal candidiasis. Sci Immunol. 2020;5: pubmed publisher
Madouri F, Barada O, Kervoaze G, Trottein F, Pichavant M, Gosset P. Production of Interleukin-20 cytokines limits bacterial clearance and lung inflammation during infection by Streptococcus pneumoniae. EBioMedicine. 2018;37:417-427 pubmed publisher
Hsu Y, Li H, Sung J, Chen W, Hou Y, Weng Y, et al. Interleukin-20 targets podocytes and is upregulated in experimental murine diabetic nephropathy. Exp Mol Med. 2017;49:e310 pubmed publisher
Treerat P, Prince O, Cruz Lagunas A, Muñoz Torrico M, Salazar Lezama M, Selman M, et al. Novel role for IL-22 in protection during chronic Mycobacterium tuberculosis HN878 infection. Mucosal Immunol. 2017;10:1069-1081 pubmed publisher
Tripathi D, Venkatasubramanian S, Cheekatla S, Paidipally P, Welch E, Tvinnereim A, et al. A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice. Nat Commun. 2016;7:13896 pubmed publisher
Justa S, Zhou X, Sarkar S. Endogenous IL-22 plays a dual role in arthritis: regulation of established arthritis via IFN-? responses. PLoS ONE. 2014;9:e93279 pubmed publisher
Kumar P, Thakar M, Ouyang W, Malarkannan S. IL-22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection. Mucosal Immunol. 2013;6:69-82 pubmed publisher
Li Z, Burns A, Miller S, Smith C. CCL20, ?? T cells, and IL-22 in corneal epithelial healing. FASEB J. 2011;25:2659-68 pubmed publisher
Lindroos J, Svensson L, Norsgaard H, Lovato P, Moller K, Hagedorn P, et al. IL-23-mediated epidermal hyperplasia is dependent on IL-6. J Invest Dermatol. 2011;131:1110-8 pubmed publisher

product information

master code :

MAB42941

SKU :

MAB42941

product name :

Mouse IL-22 R alpha 1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse IL-22 R alpha 1 Antibody from R&D Systems is a rat monoclonal antibody to IL-22R alpha 1. This antibody reacts with human,mouse. The Mouse IL-22 R alpha 1 Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready.

target :

IL-22 R alpha 1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

496514

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse IL-22 R alpha 1, Thr18-Ala228, Accession # Q80XZ4

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects mouse IL-22 R alpha 1 in direct ELISAs. In direct ELISAs, 25% cross-reactivity with recombinant human (rh) IL-22 R alpha 1 is observed and no cross-reactivity with rhIL-20 R alpha , recombinant mouse (rm) IL-20 R alpha , rhIL-22BP, or rmIL-22BP is observed.

gene symbol :

IL22RA1

top caption :

Detection of IL-22 Ra1 antibody in Hepa 1-6 Mouse Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q80XZ4

applications :

Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready

USD :

469 USD

alt names :

CRF2-9, CRF2-9interleukin 22 receptor, Cytokine receptor class-II member 9, Cytokine receptor family 2 member 9, IL-22 receptor subunit alpha-1, IL22R, IL22R alpha 1, IL22R1, IL22RA1, IL-22RA1, IL-22R-alpha-1, IL-TIF-R1, interleukin 22 receptor, alpha 1, interleukin-22 receptor subunit alpha-1, zcytoR11

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage