Human XBP1 (S Isoform) Antibody | R&D Systems MAB4257 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human XBP1 (S Isoform) Antibody

catalog :

MAB4257

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

525904

reactivity :

human, mouse

application :

western blot, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Hasegawa H, Wendling J, He F, Trilisky E, Stevenson R, Franey H, et al. In vivo crystallization of human IgG in the endoplasmic reticulum of engineered Chinese hamster ovary (CHO) cells. J Biol Chem. 2011;286:19917-31 pubmed publisher
	Zhang X, Hu P, Ding S, Sun T, Liu L, Han S, et al. Induction of autophagy-dependent apoptosis in cancer cells through activation of ER stress: an uncovered anti-cancer mechanism by anti-alcoholism drug disulfiram. Am J Cancer Res. 2019;9:1266-1281 pubmed
	Madhusudhan T, Wang H, Ghosh S, Dong W, Kumar V, Al Dabet M, et al. Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function. Blood. 2017;130:1445-1455 pubmed publisher
	Lin H, Masaki H, Yamaguchi T, Wada T, Yachie A, Nishimura K, et al. An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils. Mol Ther Methods Clin Dev. 2015;2:15046 pubmed publisher
	Klein B, Tamir H, Hirschberg D, Glickstein S, Ludwig R, Welch M. Oxytocin modulates markers of the unfolded protein response in Caco2BB gut cells. Cell Stress Chaperones. 2014;19:465-77 pubmed publisher

product information

master code :

MAB4257

SKU :

MAB4257

product name :

Human XBP1 (S Isoform) Antibody

unit size :

100 ug (also 25 ug)

description :

The Human XBP1 (S Isoform) Antibody from R&D Systems is a mouse monoclonal antibody to XBP1. This antibody reacts with human,mouse. The Human XBP1 (S Isoform) Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

XBP1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

525904

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human XBP1S, Ser188-Leu287, Accession # NP_001073007

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human XBP1 (S Isoform) (XBP1S) in direct ELISAs. This segment is found only in the XBP1S (spliced) variant. Does not detect XBP1U (unspliced).

gene symbol :

XBP1

top caption :

Detection of XBP1S antibody in RPMI 8226 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

NP_001073007

applications :

Flow Cytometry,Immunocytochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready

USD :

439 USD

alt names :

HTF, TREB5, X-box binding protein 1, X-box-binding protein 1, XBP-1, XBP2, XBP2Tax-responsive element-binding protein 5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage