product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse/Rat TNF RI/TNFRSF1A Antibody
catalog :
MAB425
quantity :
500 ug (also 25 ug)
price :
589 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
47803
reactivity :
mouse, rat
application :
western blot, ELISA
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig 5a
Wang Z, Feng J, Yu J, Chen G. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. J Cell Sci. 2019;132: pubmed publisher
Lewis R, Keilholz A, Smith C, Burd E, Nichols N. Spinal TNF-α receptor 1 is differentially required for phrenic long-term facilitation (pLTF) over the course of motor neuron death in adult rats. Front Physiol. 2024;15:1488951 pubmed publisher
Moriwaki K, Balaji S, Ka Ming Chan F. The death-inducing activity of RIPK1 is regulated by the pH environment. Sci Signal. 2020;13: pubmed publisher
Kim D, Choi J, Jo I, Kim M, Lee H, Hong S, et al. Berberine ameliorates lipopolysaccharide‑induced inflammatory responses in mouse inner medullary collecting duct‑3 cells by downregulation of NF‑κB pathway. Mol Med Rep. 2020;21:258-266 pubmed publisher
Goodall L, Ovecka M, Rycroft D, Friel S, Sanderson A, Mistry P, et al. Pharmacokinetic and Pharmacodynamic Characterisation of an Anti-Mouse TNF Receptor 1 Domain Antibody Formatted for In Vivo Half-Life Extension. PLoS ONE. 2015;10:e0137065 pubmed publisher
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed publisher
Osuchowski M, Welch K, Siddiqui J, Remick D. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality. J Immunol. 2006;177:1967-74 pubmed
Osuchowski M, Siddiqui J, Copeland S, Remick D. Sequential ELISA to profile multiple cytokines from small volumes. J Immunol Methods. 2005;302:172-81 pubmed
Ellaban E, Bolgos G, Remick D. Selective macrophage suppression during sepsis. Cell Immunol. 2004;231:103-11 pubmed
product information
master code :
MAB425
SKU :
MAB425
product name :
Mouse/Rat TNF RI/TNFRSF1A Antibody
unit size :
500 ug (also 25 ug)
description :
The Mouse/Rat TNF RI/TNFRSF1A Antibody from R&D Systems is a rat monoclonal antibody to TNF RI/TNFRSF1A. This antibody reacts with mouse,rat. The Mouse/Rat TNF RI/TNFRSF1A Antibody has been validated for the following applications: In vivo assay,ELISA Development,ELISA Development (Capture),Luminex Development,Western Blot,ELISA Capture (Matched Antibody Pair).
target :
TNF RI/TNFRSF1A
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
47803
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse TNF RI, Ile22-Ala212, Accession # P25118
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse,Rat
specificity :
Detects mouse TNF RI in ELISAs and Western blots. In ELISAs, no cross-reactivity was observed with recombinant human (rh) TNF RI, rhTNF RII, recombinant mouse TNF RII, rhTNF-alpha , recombinant rat TNF-alpha , recombinant porcine TNF-alpha , or rhTNF┐▀.
gene symbol :
TNFRSF1A
top caption :
Detection of Mouse and Rat TNF RI/TNFRSF1A antibody by Western Blot.
accessionNumbers :
P25118
applications :
In vivo assay,ELISA Development,ELISA Development (Capture),Luminex Development,Western Blot,ELISA Capture (Matched Antibody Pair)
USD :
589 USD
alt names :
CD120a, CD120a antigen, FPF, p55, p55-R, p60, TNFARMGC19588, TNF-R, TNF-R1, TNFR1TBP1, TNFR55, TNF-R55, TNFR60, TNFRI, TNF-RI, TNF-R-I, TNFR-I, TNFRSF1A, tumor necrosis factor binding protein 1, Tumor necrosis factor receptor 1, tumor necrosis factor receptor 1A isoform beta, tumor necrosis factor receptor superfamily member 1A, tumor necrosis factor receptor superfamily, member 1A, tumor necrosis factor receptor type 1, Tumor necrosis factor receptor type I, tumor necrosis factor-alpha receptor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.