Mouse/Rat DARPP-32 Antibody | R&D Systems MAB4230 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse/Rat DARPP-32 Antibody

catalog :

MAB4230

quantity :

100 ug (also 25 ug)

price :

449 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

375604

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - free floating section

more info or order :

R&D Systems product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - free floating section; mouse; loading ...; fig s2b	Stein C, McLendon J, Witmer N, Boudreau R. Modulation of miR-181 influences dopaminergic neuronal degeneration in a mouse model of Parkinson's disease. Mol Ther Nucleic Acids. 2022;28:1-15 pubmed publisher
	Singh V, Menard M, Serrano G, Beach T, Zhao H, Riley DiPaolo A, et al. Cellular and subcellular localization of Rab10 and phospho-T73 Rab10 in the mouse and human brain. Acta Neuropathol Commun. 2023;11:201 pubmed publisher
	Mansky R, Greguske E, Yu D, Zarate N, Intihar T, Tsai W, et al. Tumor suppressor p53 regulates heat shock factor 1 protein degradation in Huntington's disease. Cell Rep. 2023;42:112198 pubmed publisher
	Duvick L, Southern W, Benzow K, Handler H, Mitchell J, Kuivinen H, et al. Regional vulnerability in a neurodegenerative disease: Delineating SCA1 CNS and muscle therapeutic targets using a conditional mutant ATXN1 mouse. bioRxiv. 2023;: pubmed publisher
	Derbis M, Kul E, Niewiadomska D, Sekrecki M, Piasecka A, Taylor K, et al. Short antisense oligonucleotides alleviate the pleiotropic toxicity of RNA harboring expanded CGG repeats. Nat Commun. 2021;12:1265 pubmed publisher
	Schmidt M, Caron N, Aly A, Lemarié F, Dal Cengio L, Ko Y, et al. DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease. Front Cell Neurosci. 2020;14:590569 pubmed publisher
	Machiela E, Jeloka R, Caron N, Mehta S, Schmidt M, Baddeley H, et al. The Interaction of Aging and Cellular Stress Contributes to Pathogenesis in Mouse and Human Huntington Disease Neurons. Front Aging Neurosci. 2020;12:524369 pubmed publisher
	Carriba P, Wyatt S, Davies A. CD40L Reverse Signaling Influences Dendrite Spine Morphology and Expression of PSD-95 and Rho Small GTPases. Front Cell Dev Biol. 2020;8:254 pubmed publisher
	Burrus C, McKinstry S, Kim N, Ozlu M, Santoki A, Fang F, et al. Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival. Cell Rep. 2020;30:642-657.e6 pubmed publisher
	Caron N, Southwell A, Brouwers C, Cengio L, Xie Y, Black H, et al. Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease. Nucleic Acids Res. 2020;48:36-54 pubmed publisher
	Schmidt M, Buren C, Mackay J, Cheung D, Dal Cengio L, Raymond L, et al. Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease. BMC Biol. 2018;16:58 pubmed publisher
	Gómez Pastor R, Burchfiel E, Neef D, Jaeger A, Cabiscol E, McKinstry S, et al. Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease. Nat Commun. 2017;8:14405 pubmed publisher
	Wan Y, Ade K, Caffall Z, Ilcim Ozlu M, Eroglu C, Feng G, et al. Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder. Biol Psychiatry. 2014;75:623-30 pubmed publisher
	Chen M, Wan Y, ADE K, Ting J, Feng G, Calakos N. Sapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity. J Neurosci. 2011;31:9563-73 pubmed publisher
	Teegarden S, Scott A, Bale T. Early life exposure to a high fat diet promotes long-term changes in dietary preferences and central reward signaling. Neuroscience. 2009;162:924-32 pubmed publisher

product information

master code :

MAB4230

SKU :

MAB4230

product name :

Mouse/Rat DARPP-32 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse/Rat DARPP-32 Antibody from R&D Systems is a rat monoclonal antibody to DARPP-32. This antibody reacts with mouse,rat,transgenic mouse. The Mouse/Rat DARPP-32 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunocytochemistry.

target :

DARPP-32

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

375604

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant human DARPP-32, Ala51-Thr204, Accession # Q9UD71.2

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse,Rat,Transgenic Mouse

specificity :

Detects mouse and rat DARPP-32. Reactivity with human DARPP-32 has not been tested.

gene symbol :

PPP1R1B

top caption :

Detection of Mouse/Rat DARPP-32 antibody by Western Blot.

accessionNumbers :

Q9UD71.2

applications :

Immunohistochemistry,Western Blot,Immunocytochemistry

USD :

449 USD

alt names :

DARPP32, PPP1R1B, protein phosphatase 1, regulatory (inhibitor) subunit 1B, regulatory (inhibitor) subunit 1B (dopamine and cAMPregulated phosphoprotein, DARPP-32)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage