Human CXCR7/RDC-1 Antibody | R&D Systems MAB4227 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CXCR7/RDC-1 Antibody

catalog :

MAB4227

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

358426

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Li N, Xu H, Ou Y, Feng Z, Zhang Q, Zhu Q, et al. LPS-induced CXCR7 expression promotes gastric Cancer proliferation and migration via the TLR4/MD-2 pathway. Diagn Pathol. 2019;14:3 pubmed publisher
Montpas N, St Onge G, Nama N, Rhainds D, Benredjem B, Girard M, et al. Ligand-specific conformational transitions and intracellular transport are required for atypical chemokine receptor 3-mediated chemokine scavenging. J Biol Chem. 2018;293:893-905 pubmed publisher
Tang T, Xia Q, Xi M. CXC chemokine receptor 7 expression in cervical intraepithelial neoplasia. Biomed Rep. 2016;4:63-67 pubmed
Wang L, Chen W, Gao L, Yang Q, Liu B, Wu Z, et al. High expression of CXCR4, CXCR7 and SDF-1 predicts poor survival in renal cell carcinoma. World J Surg Oncol. 2012;10:212 pubmed publisher
Xu H, Wu Q, Dang S, Jin M, Xu J, Cheng Y, et al. Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. PLoS ONE. 2011;6:e27399 pubmed publisher
Takao T, Asanoma K, Kato K, Fukushima K, Tsunematsu R, Hirakawa T, et al. Isolation and characterization of human trophoblast side-population (SP) cells in primary villous cytotrophoblasts and HTR-8/SVneo cell line. PLoS ONE. 2011;6:e21990 pubmed publisher
Cabezón R, Sintes J, Llinàs L, Benitez Ribas D. Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. Immunol Lett. 2011;134:167-73 pubmed publisher
Berahovich R, Zabel B, Penfold M, Lewén S, Wang Y, Miao Z, et al. CXCR7 protein is not expressed on human or mouse leukocytes. J Immunol. 2010;185:5130-9 pubmed publisher

product information

master code :

MAB4227

SKU :

MAB4227

product name :

Human CXCR7/RDC-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human CXCR7/RDC-1 Antibody from R&D Systems is a mouse monoclonal antibody to CXCR7/RDC-1. This antibody reacts with human. The Human CXCR7/RDC-1 Antibody has been validated for the following applications: Neutralization,Multiplex Immunofluorescence,Flow Cytometry,Western Blot,Immunocytochemistry,Immunohistochemistry,CyTOF-ready.

target :

CXCR7/RDC-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

358426

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with human CXCR7/RDC-1, Met1-Lys362 (Gly131Ser), Accession # AAA62370

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human CXCR7/RDC-1 in direct ELISAs. In flow cytometry, reacts specifically with five distinct human CXCR7 transfectants, but does not react with their respective parental lines or mouse CXCR7 transfectants. In flow cytometry, also reacts with monocytes expressing CXCR7, but does not react with MCF-7 cells which have been reported to have surface-expressing CXCR7 using clone 11G8. Due to the conflicting reports published, use of monoclonal MAB4227 may result in an underestimation of CXCR7 expression on certain cell types.

gene symbol :

CXCR7

accessionNumbers :

AAA62370

applications :

Neutralization,Multiplex Immunofluorescence,Flow Cytometry,Western Blot,Immunocytochemistry,Immunohistochemistry,CyTOF-ready

USD :

439 USD

alt names :

ACKR3, chemokine (C-X-C motif) receptor 7, Chemokine orphan receptor 1CMKOR1C-X-C chemokine receptor type 7, CMKOR1, CXCR7, CXC-R7, CXCR-7, G protein-coupled receptor, GPR159, GPR159G-protein coupled receptor 159, RDC-1, RDC1G-protein coupled receptor RDC1 homolog

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage