Human Somatostatin R2/SSTR2 Antibody | R&D Systems MAB4224 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Somatostatin R2/SSTR2 Antibody

catalog :

MAB4224

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

402038

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 13

Reference
Carr H, Zuo Y, Frost J. The Wnt pathway protein Dvl1 targets somatostatin receptor 2 for lysosome-dependent degradation. J Biol Chem. 2023;299:104645 pubmed publisher
Mandriani B, Pell xe8 E, Mannavola F, Palazzo A, Marsano R, Ingravallo G, et al. Development of anti-somatostatin receptors CAR T cells for treatment of neuroendocrine tumors. J Immunother Cancer. 2022;10: pubmed publisher
Sim xf3 n M, J xf8 rgensen J, Khare H, Christensen C, Nielsen C, Kjaer A. Combination of [177Lu]Lu-DOTA-TATE Targeted Radionuclide Therapy and Photothermal Therapy as a Promising Approach for Cancer Treatment: In Vivo Studies in a Human Xenograft Mouse Model. Pharmaceutics. 2022;14: pubmed publisher
Dijkstra B, de Jong M, Stroet M, Andreae F, Dulfer S, Everts M, et al. Evaluation of Ac-Lys0(IRDye800CW)Tyr3-octreotate as a novel tracer for SSTR2-targeted molecular fluorescence guided surgery in meningioma. J Neurooncol. 2021;153:211-222 pubmed publisher
Agoglia R, Sun D, Birey F, Yoon S, Miura Y, Sabatini K, et al. Primate cell fusion disentangles gene regulatory divergence in neurodevelopment. Nature. 2021;592:421-427 pubmed publisher
Thakur S, Daley B, Millo C, Cochran C, Jacobson O, Lu H, et al. 177Lu-DOTA-EB-TATE, a Radiolabeled Analogue of Somatostatin Receptor Type 2, for the Imaging and Treatment of Thyroid Cancer. Clin Cancer Res. 2021;27:1399-1409 pubmed publisher
Guenter R, Aweda T, Carmona Matos D, Jang S, Whitt J, Cheng Y, et al. Overexpression of somatostatin receptor type 2 in neuroendocrine tumors for improved Ga68-DOTATATE imaging and treatment. Surgery. 2020;167:189-196 pubmed publisher
Guenter R, Aweda T, Carmona Matos D, Whitt J, Chang A, Cheng E, et al. Pulmonary Carcinoid Surface Receptor Modulation Using Histone Deacetylase Inhibitors. Cancers (Basel). 2019;11: pubmed publisher
Syu G, Wang S, Ma G, Liu S, Pearce D, Prakash A, et al. Development and application of a high-content virion display human GPCR array. Nat Commun. 2019;10:1997 pubmed publisher
Paramonov V, Desai D, Kettiger H, Mamaeva V, Rosenholm J, Sahlgren C, et al. Targeting Somatostatin Receptors By Functionalized Mesoporous Silica Nanoparticles - Are We Striking Home?. Nanotheranostics. 2018;2:320-346 pubmed publisher
Dijkstra B, Motekallemi A, den Dunnen W, Jeltema J, van Dam G, Kruyt F, et al. SSTR-2 as a potential tumour-specific marker for fluorescence-guided meningioma surgery. Acta Neurochir (Wien). 2018;160:1539-1546 pubmed publisher
Parry J, Chen R, Andrews R, Lears K, Rogers B. Identification of critical residues involved in ligand binding and G protein signaling in human somatostatin receptor subtype 2. Endocrinology. 2012;153:2747-55 pubmed publisher
Kim H, Lee H, Kim W. Clinical significance of protein expression of cyclooxygenase-2 and somatostatin receptors in gastroenteropancreatic neuroendocrine tumors. Cancer Res Treat. 2011;43:181-8 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB4224

SKU :

MAB4224

product name :

Human Somatostatin R2/SSTR2 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human Somatostatin R2/SSTR2 Antibody from R&D Systems is a mouse monoclonal antibody to Somatostatin R2/SSTR2. This antibody reacts with human,primate. The Human Somatostatin R2/SSTR2 Antibody has been validated for the following applications: Western Blot,Flow Cytometry,Immunocytochemistry,Immunohistochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

Somatostatin R2/SSTR2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

402038

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Immunohistochemistry 8-25 ug/mL, Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells, Immunocytochemistry 8-25 ug/mL, CyTOF-ready

host :

Mouse

immunogen :

NS0 mouse myeloma cell line transfected with Somatostatin R2/SSTR2, Met1-Ile369, Accession # P30874

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Primate

specificity :

Detects human Somatostatin R2/SSTR2. Stains SSTR2 transfectants but not irrelevant transfectants.

gene symbol :

SSTR2

top caption :

Somatostatin R2/SSTR2 antibody in MDA-MB-231 Human Cell Line by Immunocytochemistry (ICC).

accessionNumbers :

P30874

applications :

Immunohistochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready,Flow Cytometry,Western Blot,Immunocytochemistry

USD :

459 USD

alt names :

Smstr2, somatostatin receptor 2, somatostatin receptor type 2, SomatostatinR2, SRIF-1, SS2R, SS-2-R, SS2-R, SST2, SSTR2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage