product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Uteroglobin/SCGB1A1 Antibody
catalog :
MAB4218
quantity :
100 ug (also 25 ug)
price :
459 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
394324
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
R&D Systems product webpage
citations: 27
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 2e
Wohnhaas C, Gindele J, Kiechle T, Shen Y, Leparc G, Stierstorfer B, et al. Cigarette Smoke Specifically Affects Small Airway Epithelial Cell Populations and Triggers the Expansion of Inflammatory and Squamous Differentiation Associated Basal Cells. Int J Mol Sci. 2021;22: pubmed publisher
Kitano M, Hayashi Y, Ohnishi H, Okuyama H, Yoshimatsu M, Mizuno K, et al. Changes in the Proportion of Each Cell Type After hiPSC-Derived Airway Epithelia Transplantation. Cell Transplant. 2024;33:9636897241228026 pubmed publisher
Lee W, Lee S, Yoon J, Lee D, Kim Y, Han Y, et al. A single-cell atlas of in vitro multiculture systems uncovers the in vivo lineage trajectory and cell state in the human lung. Exp Mol Med. 2023;55:1831-1842 pubmed publisher
Chiu M, Zhang S, Li C, Liu X, Yu Y, Huang J, et al. Apical-Out Human Airway Organoids Modeling SARS-CoV-2 Infection. Viruses. 2023;15: pubmed publisher
Khatri A, Todd J, Kelly F, Nagler A, Ji Z, Jain V, et al. JAK-STAT activation contributes to cytotoxic T cell-mediated basal cell death in human chronic lung allograft dysfunction. JCI Insight. 2023;8: pubmed publisher
Kadur Lakshminarasimha Murthy P, Sontake V, Tata A, Kobayashi Y, Macadlo L, Okuda K, et al. Human distal lung maps and lineage hierarchies reveal a bipotent progenitor. Nature. 2022;604:111-119 pubmed publisher
Basil M, Cardenas Diaz F, Kathiriya J, Morley M, Carl J, Brumwell A, et al. Human distal airways contain a multipotent secretory cell that can regenerate alveoli. Nature. 2022;604:120-126 pubmed publisher
Morgan R, Manfredi C, Easley K, Watkins L, Hunt W, Goudy S, et al. A medium composition containing normal resting glucose that supports differentiation of primary human airway cells. Sci Rep. 2022;12:1540 pubmed publisher
Song H, Weinstein H, Allegakoen P, Wadsworth M, Xie J, Yang H, et al. Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states. Nat Commun. 2022;13:141 pubmed publisher
Kathiriya J, Wang C, Zhou M, Brumwell A, Cassandras M, Le Saux C, et al. Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells. Nat Cell Biol. 2021;: pubmed publisher
Rostami M, LeBlanc M, Strulovici Barel Y, Zuo W, Mezey J, O Beirne S, et al. Smoking shifts human small airway epithelium club cells toward a lesser differentiated population. NPJ Genom Med. 2021;6:73 pubmed publisher
Choi J, Jang Y, Dabrowska C, Iich E, Evans K, Hall H, et al. Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration. Nat Cell Biol. 2021;23:953-966 pubmed publisher
Stancil I, Michalski J, Davis Hall D, Chu H, Park J, Magin C, et al. Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional. Nat Commun. 2021;12:4566 pubmed publisher
Jiang M, Fang Y, Li Y, Huang H, Wei Z, Gao X, et al. VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway. Dev Cell. 2021;56:1646-1660.e5 pubmed publisher
Pohl M, Busnadiego I, Kufner V, Glas I, Karakus U, Schmutz S, et al. SARS-CoV-2 variants reveal features critical for replication in primary human cells. PLoS Biol. 2021;19:e3001006 pubmed publisher
Ernst K, Mittler A, Winkelmann V, Kling C, Eberhardt N, Anastasia A, et al. Pharmacological targeting of host chaperones protects from pertussis toxin in vitro and in vivo. Sci Rep. 2021;11:5429 pubmed publisher
Rodrigues Toste de Carvalho A, Liu H, Chen Y, Porotto M, Moscona A, Snoeck H. The in vitro multilineage differentiation and maturation of lung and airway cells from human pluripotent stem cell-derived lung progenitors in 3D. Nat Protoc. 2021;16:1802-1829 pubmed publisher
Yin X, Riva L, Pu Y, Martin Sancho L, Kanamune J, Yamamoto Y, et al. MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells. Cell Rep. 2021;34:108628 pubmed publisher
Li H, Chaitankar V, Zhu J, Chin K, Liu W, Pirooznia M, et al. Olfactomedin 4 mediation of prostate stem/progenitor-like cell proliferation and differentiation via MYC. Sci Rep. 2020;10:21924 pubmed publisher
Hao S, Ning K, Kuz C, Vorhies K, Yan Z, Qiu J. Long-Term Modeling of SARS-CoV-2 Infection of In Vitro Cultured Polarized Human Airway Epithelium. MBio. 2020;11: pubmed publisher
Youk J, Kim T, Evans K, Jeong Y, Hur Y, Hong S, et al. Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2. Cell Stem Cell. 2020;27:905-919.e10 pubmed publisher
Bluhmki T, Bitzer S, Gindele J, Schruf E, Kiechle T, Webster M, et al. Development of a miniaturized 96-Transwell air-liquid interface human small airway epithelial model. Sci Rep. 2020;10:13022 pubmed publisher
Rehman T, Thornell I, Pezzulo A, Thurman A, Romano Ibarra G, Karp P, et al. TNFα and IL-17 alkalinize airway surface liquid through CFTR and pendrin. Am J Physiol Cell Physiol. 2020;319:C331-C344 pubmed publisher
Ali M, Mori M, Mertens T, Siddhuraj P, Erjefalt J, Onnerfjord P, et al. Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells. Sci Rep. 2019;9:15566 pubmed publisher
Malvin N, Kern J, Liu T, Brody S, Stappenbeck T. Autophagy proteins are required for club cell structure and function in airways. Am J Physiol Lung Cell Mol Physiol. 2019;317:L259-L270 pubmed publisher
Henry G, Malewska A, Joseph D, Malladi V, Lee J, Torrealba J, et al. A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra. Cell Rep. 2018;25:3530-3542.e5 pubmed publisher
Winkelmann V, Thompson K, Neuland K, Jaramillo A, Fois G, Schmidt H, et al. Inflammation-induced upregulation of P2X4 expression augments mucin secretion in airway epithelia. Am J Physiol Lung Cell Mol Physiol. 2019;316:L58-L70 pubmed publisher
product information
master code :
MAB4218
SKU :
MAB4218
product name :
Human Uteroglobin/SCGB1A1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Uteroglobin/SCGB1A1 Antibody from R&D Systems is a rat monoclonal antibody to Uteroglobin/SCGB1A1. This antibody reacts with human,mouse,rat,xenograft. The Human Uteroglobin/SCGB1A1 Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunocytochemistry,Immunocytochemistry/ Immunofluorescence,Western Blot.
target :
Uteroglobin/SCGB1A1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
394324
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant human Uteroglobin/SCGB1A1, Glu22-Asn91, Accession # P11684
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Rat,Xenograft
specificity :
Detects human Uteroglobin/SCGB1A1 in direct ELISAs and Western blots.
gene symbol :
SCGB1A1
top caption :
Uteroglobin/SCGB1A1 antibody in Human Lung by Immunohistochemistry (IHC-P).
accessionNumbers :
P11684
applications :
Immunocytochemistry,Immunohistochemistry,Immunocytochemistry/ Immunofluorescence,Western Blot
USD :
459 USD
alt names :
blastokinin, CC10, CC10Urine protein 1, CC16, CCPBP, CCSP, CCSPCCPBP, Clara, Clara cell phospholipid-binding protein, Clara cells 10 kDa secretory protein, PCB-BP, SCGB1A1, Secretoglobin family 1A member 1, secretoglobin, family 1A, member 1 (uteroglobin), UGB, UGBUP-1, UP1, Urinary protein 1, uteroglobin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.