product summary
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company name :
R&D Systems
product type :
antibody
product name :
IL-17/IL-17A Antibody
catalog :
MAB421-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
453 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
50104
reactivity :
mouse
application :
western blot, neutralization
more info or order :
citations: 89
Reference
Yu D, Li T, Delpech J, Zhu B, Kishore P, Koshi T, et al. Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits. Sci Adv. 2022;8:eabm2545 pubmed publisher
Wang Y, Gao S, Gao S, Li N, Xie B, Shen X. Blocking the interaction between interleukin-17A and endoplasmic reticulum stress in macrophage attenuates retinal neovascularization in oxygen-induced retinopathy. Cell Biosci. 2021;11:82 pubmed publisher
Napier R, Lee E, Davey M, Vance E, Furtado J, Snow P, et al. T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis. Nat Commun. 2020;11:5406 pubmed publisher
Zychlinsky Scharff A, Rousseau M, Lacerda Mariano L, Canton T, Consiglio C, Albert M, et al. Sex differences in IL-17 contribute to chronicity in male versus female urinary tract infection. JCI Insight. 2019;5: pubmed publisher
Qiao S, Zhang H, Zha X, Niu W, Liang J, Pang G, et al. Endogenous IL-17A mediated neutrophil infiltration by promoting chemokines expression during chlamydial lung infection. Microb Pathog. 2019;129:106-111 pubmed publisher
Chen F, Wu W, Jin L, Millman A, Palma M, El Naccache D, et al. B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema. Cell Rep. 2018;25:2775-2783.e3 pubmed publisher
Napier R, Lee E, Vance E, Snow P, Samson K, Dawson C, et al. Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis. J Immunol. 2018;201:1889-1898 pubmed publisher
Gounder A, Yokoyama C, Jarjour N, Bricker T, Edelson B, Boon A. Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimer. PLoS Pathog. 2018;14:e1007001 pubmed publisher
Hoh B, Rojas K, Lin L, Fazal H, Hourani S, Nowicki K, et al. Estrogen Deficiency Promotes Cerebral Aneurysm Rupture by Upregulation of Th17 Cells and Interleukin-17A Which Downregulates E-Cadherin. J Am Heart Assoc. 2018;7: pubmed publisher
Lee C, Moon S, Jeong J, Lee S, Lee M, Yoo S, et al. Kaempferol targeting on the fibroblast growth factor receptor 3-ribosomal S6 kinase 2 signaling axis prevents the development of rheumatoid arthritis. Cell Death Dis. 2018;9:401 pubmed publisher
Liang C, Li C, Weng I, Chen H, Lu H, Huang C, et al. Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA Axis. Am J Pathol. 2018;188:1225-1235 pubmed publisher
Geha M, Tsokos M, Bosse R, Sannikova T, Iwakura Y, Dalle Lucca J, et al. IL-17A Produced by Innate Lymphoid Cells Is Essential for Intestinal Ischemia-Reperfusion Injury. J Immunol. 2017;199:2921-2929 pubmed publisher
Garth J, Reeder K, Godwin M, Mackel J, Dunaway C, Blackburn J, et al. IL-33 Signaling Regulates Innate IL-17A and IL-22 Production via Suppression of Prostaglandin E2 during Lung Fungal Infection. J Immunol. 2017;199:2140-2148 pubmed publisher
Davicino R, Méndez Huergo S, Eliçabe R, Stupirski J, Autenrieth I, Di Genaro M, et al. Galectin-1-Driven Tolerogenic Programs Aggravate Yersinia enterocolitica Infection by Repressing Antibacterial Immunity. J Immunol. 2017;199:1382-1392 pubmed publisher
Zou J, Qin J, Li Y, Wang Y, Li D, Shu Y, et al. IL-35 induces N2 phenotype of neutrophils to promote tumor growth. Oncotarget. 2017;8:33501-33514 pubmed publisher
Okuyama H, Tominaga A, Fukuoka S, Taguchi T, Kusumoto Y, Ono S. Spirulina lipopolysaccharides inhibit tumor growth in a Toll-like receptor 4-dependent manner by altering the cytokine milieu from interleukin-17/interleukin-23 to interferon-?. Oncol Rep. 2017;37:684-694 pubmed publisher
Qiu A, Bian Z, Mao P, Liu Q. IL-17A exacerbates diabetic retinopathy by impairing Müller cell function via Act1 signaling. Exp Mol Med. 2016;48:e280 pubmed publisher
Subbarayal B, Chauhan S, Di Zazzo A, Dana R. IL-17 Augments B Cell Activation in Ocular Surface Autoimmunity. J Immunol. 2016;197:3464-3470 pubmed
Quirino G, Nascimento M, Davoli Ferreira M, Sacramento L, Lima M, Almeida R, et al. Interleukin-27 (IL-27) Mediates Susceptibility to Visceral Leishmaniasis by Suppressing the IL-17-Neutrophil Response. Infect Immun. 2016;84:2289-2298 pubmed publisher
Song Z, Li Z, Li D, Fang W, Liu H, Yang D, et al. Seminal plasma induces inflammation in the uterus through the ?? T/IL-17 pathway. Sci Rep. 2016;6:25118 pubmed publisher
Porcherie A, Gilbert F, Germon P, Cunha P, Trotereau A, Rossignol C, et al. IL-17A Is an Important Effector of the Immune Response of the Mammary Gland to Escherichia coli Infection. J Immunol. 2016;196:803-12 pubmed publisher
Ishizuka M, Miyazaki Y, Masuo M, Suhara K, Tateishi T, Yasui M, et al. Interleukin-17A and Neutrophils in a Murine Model of Bird-Related Hypersensitivity Pneumonitis. PLoS ONE. 2015;10:e0137978 pubmed publisher
Liu Y, Li K, Yang L, Tang S, Wang X, Cao G, et al. Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia. PLoS ONE. 2015;10:e0136214 pubmed publisher
Murphy S, Schaeffer A, Done J, Wong L, Bell Cohn A, Roman K, et al. IL17 Mediates Pelvic Pain in Experimental Autoimmune Prostatitis (EAP). PLoS ONE. 2015;10:e0125623 pubmed publisher
Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N. Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency. J Immunol. 2015;194:5407-16 pubmed publisher
Yang B, Liu R, Yang T, Jiang X, Zhang L, Wang L, et al. Neonatal Streptococcus pneumoniae infection may aggravate adulthood allergic airways disease in association with IL-17A. PLoS ONE. 2015;10:e0123010 pubmed publisher
Kim Y, Lim H, Jung H, Wetsel R, Chung Y. Regulation of autoimmune germinal center reactions in lupus-prone BXD2 mice by follicular helper T cells. PLoS ONE. 2015;10:e0120294 pubmed publisher
Qi H, Yang H, Xu G, Ren J, Hua W, Shi Y, et al. Therapeutic efficacy of IL-17A antibody injection in preventing the development of colitis associated carcinogenesis in mice. Immunobiology. 2015;220:54-9 pubmed publisher
Tilahun A, Chowdhary V, David C, Rajagopalan G. Systemic inflammatory response elicited by superantigen destabilizes T regulatory cells, rendering them ineffective during toxic shock syndrome. J Immunol. 2014;193:2919-30 pubmed publisher
Mathews J, Williams A, Brand J, Wurmbrand A, Chen L, Ninin F, et al. γδ T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFα. PLoS ONE. 2014;9:e97707 pubmed publisher
Akiyama T, Miyamoto Y, Yoshimura K, Yamada A, Takami M, Suzawa T, et al. Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-α and interleukin-1β but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gin. J Biol Chem. 2014;289:15621-30 pubmed publisher
Klein M, Brouwer M, Angele B, Geldhoff M, Marquez G, Varona R, et al. Leukocyte attraction by CCL20 and its receptor CCR6 in humans and mice with pneumococcal meningitis. PLoS ONE. 2014;9:e93057 pubmed publisher
Tseng J, Yang C, Liang S, Liu R, Yang S, Lin J, et al. Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases. Clin Cancer Res. 2014;20:2885-97 pubmed publisher
Bi Y, Zhou J, Yang H, Wang X, Zhang X, Wang Q, et al. IL-17A produced by neutrophils protects against pneumonic plague through orchestrating IFN-?-activated macrophage programming. J Immunol. 2014;192:704-13 pubmed publisher
Chong S, Tan K, Wong F, Chua Y, Tang Y, Ng L, et al. CD8 T cells regulate allergic contact dermatitis by modulating CCR2-dependent TNF/iNOS-expressing Ly6C+ CD11b+ monocytic cells. J Invest Dermatol. 2014;134:666-676 pubmed publisher
Bonnegarde Bernard A, Jee J, Fial M, Aeffner F, Cormet Boyaka E, Davis I, et al. IKK? in intestinal epithelial cells regulates allergen-specific IgA and allergic inflammation at distant mucosal sites. Mucosal Immunol. 2014;7:257-67 pubmed publisher
Wu S, Yu J, Liu F, Miaw S, Wu Hsieh B. Galectin-3 negatively regulates dendritic cell production of IL-23/IL-17-axis cytokines in infection by Histoplasma capsulatum. J Immunol. 2013;190:3427-37 pubmed publisher
Singh T, Schön M, Wallbrecht K, Gruber Wackernagel A, Wang X, Wolf P. Involvement of IL-9 in Th17-associated inflammation and angiogenesis of psoriasis. PLoS ONE. 2013;8:e51752 pubmed publisher
Ano S, Morishima Y, Ishii Y, Yoh K, Yageta Y, Ohtsuka S, et al. Transcription factors GATA-3 and ROR?t are important for determining the phenotype of allergic airway inflammation in a murine model of asthma. J Immunol. 2013;190:1056-65 pubmed publisher
Hou L, Jie Z, Desai M, Liang Y, Soong L, Wang T, et al. Early IL-17 production by intrahepatic T cells is important for adaptive immune responses in viral hepatitis. J Immunol. 2013;190:621-9 pubmed publisher
Noto Llana M, Sarnacki S, Vázquez M, Gartner A, Giacomodonato M, Cerquetti M. Salmonella enterica induces joint inflammation and expression of interleukin-17 in draining lymph nodes early after onset of enterocolitis in mice. Infect Immun. 2012;80:2231-9 pubmed publisher
Khader S, Guglani L, Rangel Moreno J, Gopal R, Junecko B, Fountain J, et al. IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung. J Immunol. 2011;187:5402-7 pubmed publisher
Park S, Gupta D, Kim C, Dziarski R. Differential effects of peptidoglycan recognition proteins on experimental atopic and contact dermatitis mediated by Treg and Th17 cells. PLoS ONE. 2011;6:e24961 pubmed publisher
Kim H, Go H, Akira S, Chung D. TLR2-mediated production of IL-27 and chemokines by respiratory epithelial cells promotes bleomycin-induced pulmonary fibrosis in mice. J Immunol. 2011;187:4007-17 pubmed publisher
Breslow J, Meissler J, Hartzell R, Spence P, Truant A, Gaughan J, et al. Innate immune responses to systemic Acinetobacter baumannii infection in mice: neutrophils, but not interleukin-17, mediate host resistance. Infect Immun. 2011;79:3317-27 pubmed publisher
Ma Y, Aymeric L, Locher C, Mattarollo S, Delahaye N, Pereira P, et al. Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J Exp Med. 2011;208:491-503 pubmed publisher
Shen H, Harris G, Chen W, Sjostedt A, Ryden P, Conlan W. Molecular immune responses to aerosol challenge with Francisella tularensis in mice inoculated with live vaccine candidates of varying efficacy. PLoS ONE. 2010;5:e13349 pubmed publisher
Gao Q, Jiang Y, Ma T, Zhu F, Gao F, Zhang P, et al. A critical function of Th17 proinflammatory cells in the development of atherosclerotic plaque in mice. J Immunol. 2010;185:5820-7 pubmed publisher
Wondimu Z, Santodomingo Garzon T, Le T, Swain M. Protective role of interleukin-17 in murine NKT cell-driven acute experimental hepatitis. Am J Pathol. 2010;177:2334-46 pubmed publisher
Eliçabe R, Cargnelutti E, Serer M, Stege P, Valdez S, Toscano M, et al. Lack of TNFR p55 results in heightened expression of IFN-? and IL-17 during the development of reactive arthritis. J Immunol. 2010;185:4485-95 pubmed publisher
De Latour R, Visconte V, Takaku T, Wu C, Erie A, Sarcon A, et al. Th17 immune responses contribute to the pathophysiology of aplastic anemia. Blood. 2010;116:4175-84 pubmed publisher
Cruz A, Fraga A, Fountain J, Rangel Moreno J, Torrado E, Saraiva M, et al. Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis. J Exp Med. 2010;207:1609-16 pubmed publisher
Redford P, Boonstra A, Read S, Pitt J, Graham C, Stavropoulos E, et al. Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung. Eur J Immunol. 2010;40:2200-10 pubmed publisher
De Luca A, Zelante T, D Angelo C, Zagarella S, Fallarino F, Spreca A, et al. IL-22 defines a novel immune pathway of antifungal resistance. Mucosal Immunol. 2010;3:361-73 pubmed publisher
Lo Re S, Dumoutier L, Couillin I, Van Vyve C, Yakoub Y, Uwambayinema F, et al. IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis. J Immunol. 2010;184:6367-77 pubmed publisher
Horvat J, Starkey M, Kim R, Beagley K, Preston J, Gibson P, et al. Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease. J Immunol. 2010;184:4159-69 pubmed publisher
Li L, Huang L, Vergis A, Ye H, Bajwa A, Narayan V, et al. IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury. J Clin Invest. 2010;120:331-42 pubmed publisher
Han G, Wang R, Chen G, Wang J, Xu R, Wang L, et al. Interleukin-17-producing gammadelta+ T cells protect NOD mice from type 1 diabetes through a mechanism involving transforming growth factor-beta. Immunology. 2010;129:197-206 pubmed publisher
He R, Kim H, Yoon J, Oyoshi M, MacGinnitie A, Goya S, et al. Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13. J Allergy Clin Immunol. 2009;124:761-70.e1 pubmed publisher
Bai H, Cheng J, Gao X, Joyee A, Fan Y, Wang S, et al. IL-17/Th17 promotes type 1 T cell immunity against pulmonary intracellular bacterial infection through modulating dendritic cell function. J Immunol. 2009;183:5886-95 pubmed publisher
Tigno Aranjuez J, Jaini R, Tuohy V, Lehmann P, Tary Lehmann M. Encephalitogenicity of complete Freund's adjuvant relative to CpG is linked to induction of Th17 cells. J Immunol. 2009;183:5654-61 pubmed publisher
Oyoshi M, Elkhal A, Kumar L, Scott J, Koduru S, He R, et al. Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response. Proc Natl Acad Sci U S A. 2009;106:14954-9 pubmed publisher
Wu S, Rhee K, Albesiano E, RABIZADEH S, Wu X, Yen H, et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med. 2009;15:1016-22 pubmed publisher
Park S, Lee K, Kim S, Min K, Choe Y, Moon H, et al. Peroxisome proliferator-activated receptor gamma agonist down-regulates IL-17 expression in a murine model of allergic airway inflammation. J Immunol. 2009;183:3259-67 pubmed publisher
Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton M, et al. A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum. J Immunol. 2009;183:1291-300 pubmed publisher
Yuan X, Ansari M, D Addio F, Paez Cortez J, Schmitt I, Donnarumma M, et al. Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells. Proc Natl Acad Sci U S A. 2009;106:10734-9 pubmed publisher
Hamada H, Garcia Hernandez M, Reome J, Misra S, Strutt T, McKinstry K, et al. Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge. J Immunol. 2009;182:3469-81 pubmed publisher
Zhang Z, Zhong W, Spencer D, Chen H, Lu H, Kawaguchi T, et al. Interleukin-17 causes neutrophil mediated inflammation in ovalbumin-induced uveitis in DO11.10 mice. Cytokine. 2009;46:79-91 pubmed publisher
Otani K, Watanabe T, Tanigawa T, Okazaki H, Yamagami H, Watanabe K, et al. Anti-inflammatory effects of IL-17A on Helicobacter pylori-induced gastritis. Biochem Biophys Res Commun. 2009;382:252-8 pubmed publisher
Chauhan S, El Annan J, Ecoiffier T, Goyal S, Zhang Q, Saban D, et al. Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression. J Immunol. 2009;182:1247-52 pubmed
Egan P, van Nieuwenhuijze A, Campbell I, Wicks I. Promotion of the local differentiation of murine Th17 cells by synovial macrophages during acute inflammatory arthritis. Arthritis Rheum. 2008;58:3720-9 pubmed publisher
Koenders M, Devesa I, Marijnissen R, Abdollahi Roodsaz S, Boots A, Walgreen B, et al. Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice. Arthritis Rheum. 2008;58:3461-70 pubmed publisher
Burrell B, Csencsits K, Lu G, Grabauskiene S, Bishop D. CD8+ Th17 mediate costimulation blockade-resistant allograft rejection in T-bet-deficient mice. J Immunol. 2008;181:3906-14 pubmed
Mauermann N, Burian J, von Garnier C, Dirnhofer S, Germano D, Schuett C, et al. Interferon-gamma regulates idiopathic pneumonia syndrome, a Th17+CD4+ T-cell-mediated graft-versus-host disease. Am J Respir Crit Care Med. 2008;178:379-88 pubmed publisher
Lee K, Kang M, Lee Y, Kim Y, Kim D, Ko H, et al. A distinct subset of natural killer T cells produces IL-17, contributing to airway infiltration of neutrophils but not to airway hyperreactivity. Cell Immunol. 2008;251:50-5 pubmed publisher
Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D Angelo C, et al. Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection. J Immunol. 2008;180:4022-31 pubmed
Iwanami K, Matsumoto I, Tanaka Watanabe Y, Inoue A, Mihara M, Ohsugi Y, et al. Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase. Arthritis Rheum. 2008;58:754-63 pubmed publisher
Romani L, Fallarino F, De Luca A, Montagnoli C, D Angelo C, Zelante T, et al. Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. Nature. 2008;451:211-5 pubmed publisher
Irmler I, Gajda M, Bräuer R. Exacerbation of antigen-induced arthritis in IFN-gamma-deficient mice as a result of unrestricted IL-17 response. J Immunol. 2007;179:6228-36 pubmed
Zelante T, De Luca A, Bonifazi P, Montagnoli C, Bozza S, Moretti S, et al. IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur J Immunol. 2007;37:2695-706 pubmed
He R, Oyoshi M, Jin H, Geha R. Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge. Proc Natl Acad Sci U S A. 2007;104:15817-22 pubmed
Harris T, Grosso J, Yen H, Xin H, Kortylewski M, Albesiano E, et al. Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity. J Immunol. 2007;179:4313-7 pubmed
Kohyama S, Ohno S, Isoda A, Moriya O, Belladonna M, Hayashi H, et al. IL-23 enhances host defense against vaccinia virus infection via a mechanism partly involving IL-17. J Immunol. 2007;179:3917-25 pubmed
Shibata K, Yamada H, Hara H, Kishihara K, Yoshikai Y. Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 production. J Immunol. 2007;178:4466-72 pubmed
Fujiwara M, Hirose K, Kagami S, Takatori H, Wakashin H, Tamachi T, et al. T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways. J Allergy Clin Immunol. 2007;119:662-70 pubmed
Ivanov S, Bozinovski S, Bossios A, Valadi H, Vlahos R, Malmhäll C, et al. Functional relevance of the IL-23-IL-17 axis in lungs in vivo. Am J Respir Cell Mol Biol. 2007;36:442-51 pubmed
Sergejeva S, Ivanov S, Lotvall J, Linden A. Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation. Am J Respir Cell Mol Biol. 2005;33:248-53 pubmed
Burchill M, Nardelli D, England D, DeCoster D, Christopherson J, Callister S, et al. Inhibition of interleukin-17 prevents the development of arthritis in vaccinated mice challenged with Borrelia burgdorferi. Infect Immun. 2003;71:3437-42 pubmed
Miyamoto M, Prause O, Sjöstrand M, Laan M, Lotvall J, Linden A. Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways. J Immunol. 2003;170:4665-72 pubmed
image
image 1 :
R&D Systems MAB421-100 image 1
Detection of Recombinant Mouse IL-17/IL-17A antibody by Western Blot.
product information
brand :
R&D Systems
master code :
MAB421
SKU :
MAB421-100
product name :
IL-17/IL-17A Antibody
description :
The Mouse IL-17/IL-17A Antibody from R&D Systems is a rat monoclonal antibody to IL-17/IL-17A. This antibody reacts with mouse. The Mouse IL-17/IL-17A Antibody has been validated for the following applications: Western Blot, Neutralization.
target :
IL-17/IL-17A
category :
Primary Antibodies
unit sizes :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
50104
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse IL-17, Thr22-Ala158, Accession # Q62386
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse IL-17 in direct ELISAs and Western blots. In direct ELISAs, 100% reactivity with recombinant rat IL-17A and approximately 40% reactivity with recombinant mouse (rm) IL-17A/IL-17F heterodimer is observed. No cross-reactivity with recombinant human IL-17, recombinant canine IL-17, rmIL-17B, rmIL-17C, rmIL-17D, rmIL-17E, or rmIL-17F is observed.
gene symbol :
IL17A
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
Q62386
applications :
Western Blot, Neutralization
USD :
453 USD
alt names :
CTLA8, CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, IL17interleukin-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.