CCL11/Eotaxin Antibody | R&D Systems MAB420-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

CCL11/Eotaxin Antibody

catalog :

MAB420-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

469 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

42285

reactivity :

mouse

application :

western blot, immunohistochemistry, neutralization

more info or order :

R&D Systems product webpage

citations: 6

Reference
Scabia G, Testa G, Scali M, Del Turco S, Desiato G, Berardi N, et al. Reduced ccl11/eotaxin mediates the beneficial effects of environmental stimulation on the aged hippocampus. Brain Behav Immun. 2021;98:234-244 pubmed publisher
Wang F, Baba N, Shen Y, Yamashita T, Tsuru E, Tsuda M, et al. CCL11 promotes migration and proliferation of mouse neural progenitor cells. Stem Cell Res Ther. 2017;8:26 pubmed publisher
Chandra G, Rangasamy S, Roy A, Kordower J, Pahan K. Neutralization of RANTES and Eotaxin Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson Disease. J Biol Chem. 2016;291:15267-81 pubmed publisher
Villeda S, Luo J, Mosher K, Zou B, Britschgi M, Bieri G, et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature. 2011;477:90-4 pubmed publisher
Barlow J, Flynn R, Ballantyne S, McKenzie A. Reciprocal expression of IL-25 and IL-17A is important for allergic airways hyperreactivity. Clin Exp Allergy. 2011;41:1447-55 pubmed publisher
Wakashin H, Hirose K, Maezawa Y, Kagami S, Suto A, Watanabe N, et al. IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice. Am J Respir Crit Care Med. 2008;178:1023-32 pubmed publisher

image

image 1 :

Chemotaxis Induced by CCL11/Eotaxin and Neutralization by Mouse CCL11/Eotaxin Antibody.

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB420

SKU :

MAB420-100

product name :

CCL11/Eotaxin Antibody

Description :

The Mouse CCL11/Eotaxin Antibody from R&D Systems is a rat monoclonal antibody to CCL11/Eotaxin. This antibody reacts with mouse. The Mouse CCL11/Eotaxin Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Neutralization.

target :

CCL11/Eotaxin

category :

Primary Antibodies

unit size :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

42285

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse CCL11/Eotaxin, His24-Pro97, Accession # P48298

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse CCL11/Eotaxin in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant human (rh) CCL11/Eotaxin, recombinant mouse CCL7, and rhCCL21 is observed.

gene symbol :

CCL11

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

P48298

applications :

Western Blot, Immunohistochemistry, Neutralization

USD :

469 USD

alt names :

C-C motif chemokine 11, chemokine (C-C motif) ligand 11, Eosinophil chemotactic protein, Eotaxin, eotaxin-1, MGC22554, SCYA11Small-inducible cytokine A11, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage