product summary
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company name :
R&D Systems
product type :
antibody
product name :
IL-12 p70 Antibody
catalog :
MAB419-100
quantity :
100 ug (also 500 ug, 25 ug)
price :
459 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
48110
reactivity :
mouse
application :
western blot, ELISA
more info or order :
R&D Systems product webpage
citations: 14
Reference
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Matalka K, Abdulridha N, Badr M, Mansoor K, Qinna N, Qadan F. Eriobotrya japonica Water Extract Characterization: An Inducer of Interferon-Gamma Production Mainly by the JAK-STAT Pathway. Molecules. 2016;21: pubmed publisher
Badr M, Qinna N, Qadan F, Matalka K. Dichloroacetate modulates cytokines toward T helper 1 function via induction of the interleukin-12-interferon-γ pathway. Onco Targets Ther. 2014;7:193-201 pubmed publisher
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, et al. Response patterns of cytokines/chemokines in two murine strains after irradiation. Cytokine. 2012;58:169-77 pubmed publisher
Jin W, Qi S, Luo H. The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function. BMC Immunol. 2011;12:68 pubmed publisher
Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, et al. NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity. J Immunol. 2008;181:7157-65 pubmed
Liu J, Dolan M, Reidy M, Cramer C. Expression of bioactive single-chain murine IL-12 in transgenic plants. J Interferon Cytokine Res. 2008;28:381-92 pubmed publisher
Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, et al. Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis. J Immunol. 2006;177:8650-7 pubmed
Chiang Y, Chang C, Chang S, Yang W, Shyur L. Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator. J Ethnopharmacol. 2007;110:532-8 pubmed
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An H, Jeong H, Um J, Kim H, Hong S. Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages. J Ethnopharmacol. 2006;106:418-24 pubmed
Osuchowski M, Siddiqui J, Copeland S, Remick D. Sequential ELISA to profile multiple cytokines from small volumes. J Immunol Methods. 2005;302:172-81 pubmed
Rosini L, Matlack R, Taylor J, Howell K, Yeh K, Pennello A, et al. Nonlymphoid peritoneal cells suppress the T cell response to Mls. Immunobiology. 2004;209:575-84 pubmed
Bengtsson A, Ryan E, Giordano D, Magaletti D, Clark E. 17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells. Blood. 2004;104:1404-10 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB419
SKU :
MAB419-100
product name :
IL-12 p70 Antibody
Description :
The Mouse IL-12 p70 Antibody from R&D Systems is a rat monoclonal antibody to IL-12 p70/IL-12A. This antibody reacts with mouse. The Mouse IL-12 p70 Antibody has been validated for the following applications: Western Blot, ELISA Capture (Matched Antibody Pair).
target :
IL-12 p70
category :
Primary Antibodies
unit size :
100 ug (also 500 ug, 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
48110
conjugate :
Unconjugated
host :
Rat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse IL-12
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse IL-12 in ELISAs and Western blots. Detects an epitope in the p35 subunit. In sandwich ELISAs, does not cross-react with recombinant mouse IL-12 p40.
gene symbol :
IL12A
applications :
Western Blot, ELISA Capture (Matched Antibody Pair)
USD :
459 USD
alt names :
CLMF p35, CLMF1, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL12, IL12 p70, IL-12 subunit p35, IL-12, subunit p35, IL12A, interleukin 12, p35, interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p35), interleukin-12 alpha chain, interleukin-12 subunit alpha, natural killer cell stimulatory factor 1, 35 kD subunit, NF cell stimulatory factor chain 1, NK cell stimulatory factor chain 1, NKSF1, p35
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.