product summary
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company name :
R&D Systems
product type :
antibody
product name :
IL-11 Antibody
catalog :
MAB418
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
188520
reactivity :
mouse
application :
western blot, neutralization
more info or order :
citations: 3
Reference
Zhang X, Kiapour N, Kapoor S, Khan T, Thamilarasan M, Tao Y, et al. IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis. J Immunol. 2019;203:1142-1150 pubmed publisher
Kim J, Kim M, Ham A, Brown K, Greene R, D Agati V, et al. IL-11 is required for A1 adenosine receptor-mediated protection against ischemic AKI. J Am Soc Nephrol. 2013;24:1558-70 pubmed publisher
Mitchell H, White D, Domowicz M, Kraig R. Cold pre-conditioning neuroprotection depends on TNF-? and is enhanced by blockade of interleukin-11. J Neurochem. 2011;117:187-96 pubmed publisher
image
image 1 :
R&D Systems MAB418 image 1
Cell Proliferation Induced by IL-11 and Neutralization by Mouse IL-11 Antibody.
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB418
SKU :
MAB418
product name :
IL-11 Antibody
Description :
The Mouse IL-11 Antibody from R&D Systems is a rat monoclonal antibody to IL-11. This antibody reacts with mouse. The Mouse IL-11 Antibody has been validated for the following applications: Western Blot, Neutralization.
target :
IL-11
category :
Primary Antibodies
unit size :
500 ug (also 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
188520
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse IL-11, Gly23-Leu199, Accession # P47873
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse IL-11 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 10-20% cross-reactivity with recombinant human (rh) IL-11 is observed and no cross-reactivity with recombinant rat CNTF, recombinant mouse (rm) IL-6, rmLIF, rmOSM, rmCT-1, or rhCLC is observed.
gene symbol :
IL11
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P47873
applications :
Western Blot, Neutralization
USD :
559 USD
alt names :
Adipogenesis inhibitory factor, AGIF, AGIFoprelvekin, IL11, IL-11Oprelvekin, interleukin 11, interleukin-11, Oprelvekin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.