IL-10 Antibody | R&D Systems MAB417-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

IL-10 Antibody

catalog :

MAB417-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

453 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

JES052A5

reactivity :

mouse

application :

western blot, ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 42

Reference
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Na Y, Kwon J, Kim D, Chung H, Song J, Jung D, et al. Protein Kinase A Catalytic Subunit Is a Molecular Switch that Promotes the Pro-tumoral Function of Macrophages. Cell Rep. 2020;31:107643 pubmed publisher
Zhao Y, Wang J, Min Z, Peng L, Qi S, Lin W. I-alowCD11bhigh DC Regulates the Immune Response in the Eyes of Experimental Autoimmune Uveitis. Mediators Inflamm. 2020;2020:6947482 pubmed publisher
Wang B, Wu S, Ma Z, Wang T, Yang C. BMSCs pre-treatment ameliorates inflammation-related tissue destruction in LPS-induced rat DIC model. Cell Death Dis. 2018;9:1024 pubmed publisher
Tian L, Song S, Zhu B, Liu S. Electroacupuncture at ST-36 Protects Interstitial Cells of Cajal via Sustaining Heme Oxygenase-1 Positive M2 Macrophages in the Stomach of Diabetic Mice. Oxid Med Cell Longev. 2018;2018:3987134 pubmed publisher
Dyck S, Kataria H, Alizadeh A, Santhosh K, Lang B, Silver J, et al. Perturbing chondroitin sulfate proteoglycan signaling through LAR and PTPσ receptors promotes a beneficial inflammatory response following spinal cord injury. J Neuroinflammation. 2018;15:90 pubmed publisher
Foubert P, Kaneda M, Varner J. PI3Kγ Activates Integrin α4 and Promotes Immune Suppressive Myeloid Cell Polarization during Tumor Progression. Cancer Immunol Res. 2017;5:957-968 pubmed publisher
Li L, Labuda J, Imai D, Griffey S, McSorley S. CCR7 Deficiency Allows Accelerated Clearance of Chlamydia from the Female Reproductive Tract. J Immunol. 2017;199:2547-2554 pubmed publisher
Nascimento D, Melo P, Piñeros A, Ferreira R, Cólon D, Donate P, et al. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population. Nat Commun. 2017;8:14919 pubmed publisher
Dawicki W, Li C, Town J, Zhang X, Gordon J. Therapeutic reversal of food allergen sensitivity by mature retinoic acid-differentiated dendritic cell induction of LAG3+CD49b-Foxp3- regulatory T cells. J Allergy Clin Immunol. 2017;139:1608-1620.e3 pubmed publisher
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Lim J, Im K, Lee E, Kim N, Nam Y, Jeon Y, et al. Enhanced immunoregulation of mesenchymal stem cells by IL-10-producing type 1 regulatory T cells in collagen-induced arthritis. Sci Rep. 2016;6:26851 pubmed publisher
Besnard A, Guabiraba R, Niedbala W, Palomo J, Reverchon F, Shaw T, et al. IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells. PLoS Pathog. 2015;11:e1004607 pubmed publisher
McKelvey R, Berta T, Old E, Ji R, Fitzgerald M. Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation. J Neurosci. 2015;35:457-66 pubmed publisher
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image

image 1 :

Detection of Recombinant Mouse IL-10 antibody by Western Blot.

product information

brand :

R&D Systems

master code :

MAB417

SKU :

MAB417-100

product name :

IL-10 Antibody

description :

The Mouse IL-10 Antibody from R&D Systems is a rat monoclonal antibody to IL-10. This antibody reacts with mouse. The Mouse IL-10 Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

IL-10

category :

Primary Antibodies

unit sizes :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

JES052A5

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse IL-10, Accession # P18893

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse IL-10 in sandwich ELISAs and Western blots. In sandwich ELISAs, less than 8% cross-reactivity with recombinant rat IL-10 and 1% cross-reactivity with recombinant cotton rat IL-10 is observed. In sandwich ELISAs, no cross-reactivity with recombinant human (rh) IL-10, recombinant mouse IL-10 R, rhIL-10 R, recombinant canine IL-10, recombinant feline IL-10, or recombinant porcine IL-10 is observed.

gene symbol :

IL10

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

P18893

applications :

Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)

USD :

453 USD

alt names :

CSIF, CSIFMGC126450, Cytokine synthesis inhibitory factor, GVHDS, IL10, IL10A, IL-10MGC126451, interleukin 10, interleukin-10, TGIF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage