Mouse M-CSF Antibody | R&D Systems MAB416-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse M-CSF Antibody

catalog :

MAB416-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

131621

reactivity :

human, mouse

application :

ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 5

Reference
Moon H, Kim S, Jeong J, Han S, Jarjour N, Lee H, et al. Airway Epithelial Cell-Derived Colony Stimulating Factor-1 Promotes Allergen Sensitization. Immunity. 2018;49:275-287.e5 pubmed publisher
Tang J, Frey J, Wilson C, Moncada Pazos A, Levet C, Freeman M, et al. Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation. Mol Cell Biol. 2018;38: pubmed publisher
Kumar V, Donthireddy L, Marvel D, Condamine T, Wang F, Lavilla Alonso S, et al. Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors. Cancer Cell. 2017;32:654-668.e5 pubmed publisher
Rothhammer V, Mascanfroni I, Bunse L, Takenaka M, Kenison J, Mayo L, et al. Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor. Nat Med. 2016;22:586-97 pubmed publisher
Escamilla J, Schokrpur S, Liu C, Priceman S, Moughon D, Jiang Z, et al. CSF1 receptor targeting in prostate cancer reverses macrophage-mediated resistance to androgen blockade therapy. Cancer Res. 2015;75:950-62 pubmed publisher

product information

master code :

MAB416

SKU :

MAB416-100

product name :

Mouse M-CSF Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Mouse M-CSF Antibody from R&D Systems is a rat monoclonal antibody to M-CSF. This antibody reacts with human,mouse. The Mouse M-CSF Antibody has been validated for the following applications: Immunohistochemistry,ELISA Development (Capture),Neutralization,ELISA Capture (Matched Antibody Pair).

target :

M-CSF

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

131621

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse M-CSF, Lys33-Glu262 (predicted), Accession # P07141

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse M-CSF in ELISAs. In sandwich immunoassays, no cross-reactivity with recombinant human M-CSF, recombinant mouse (rm) SCF, rmFlt-3 Ligand, rmG-CSF, and rmGM-CSF is observed.

gene symbol :

CSF1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by M-CSF and Neutralization by Mouse M-CSF Antibody.

accessionNumbers :

P07141

applications :

ELISA Development (Capture),Neutralization,ELISA Capture (Matched Antibody Pair)

USD :

459 USD

alt names :

colony stimulating factor 1 (macrophage), CSF1, CSF-1, Lanimostim, macrophage colony stimulating factor, macrophage colony-stimulating factor 1, MCSF, M-CSF, MCSFlanimostim, MGC31930

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage