IL-13 Antibody | R&D Systems MAB413-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

IL-13 Antibody

catalog :

MAB413-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

442 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

38213

reactivity :

mouse

application :

western blot, ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 12

Reference
Zhao J, Okamoto Y, Asano Y, Ishimaru K, Aki S, Yoshioka K, et al. Sphingosine-1-phosphate receptor-2 facilitates pulmonary fibrosis through potentiating IL-13 pathway in macrophages. PLoS ONE. 2018;13:e0197604 pubmed publisher
Damle S, Martin R, Cross J, Conrad D. Macrophage migration inhibitory factor deficiency enhances immune response to Nippostrongylus brasiliensis. Mucosal Immunol. 2017;10:205-214 pubmed publisher
Knudson C, Hartwig S, Meyerholz D, Varga S. RSV vaccine-enhanced disease is orchestrated by the combined actions of distinct CD4 T cell subsets. PLoS Pathog. 2015;11:e1004757 pubmed publisher
Zhang X, Schaumburg C, Coursey T, Siemasko K, Volpe E, Gandhi N, et al. CD8? cells regulate the T helper-17 response in an experimental murine model of Sjögren syndrome. Mucosal Immunol. 2014;7:417-27 pubmed publisher
Mosconi E, Rekima A, Seitz Polski B, Kanda A, Fleury S, Tissandie E, et al. Breast milk immune complexes are potent inducers of oral tolerance in neonates and prevent asthma development. Mucosal Immunol. 2010;3:461-74 pubmed publisher
Horvat J, Starkey M, Kim R, Beagley K, Preston J, Gibson P, et al. Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease. J Immunol. 2010;184:4159-69 pubmed publisher
Neveu W, Allard J, Dienz O, Wargo M, Ciliberto G, Whittaker L, et al. IL-6 is required for airway mucus production induced by inhaled fungal allergens. J Immunol. 2009;183:1732-8 pubmed publisher
Daniel C, Sartory N, Zahn N, Schmidt R, Geisslinger G, Radeke H, et al. FTY720 ameliorates oxazolone colitis in mice by directly affecting T helper type 2 functions. Mol Immunol. 2007;44:3305-16 pubmed
Pierce J, Rir Sima Ah J, Estrada I, Wilder J, Strasser A, Tesfaigzi Y. Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia. Am J Physiol Lung Cell Mol Physiol. 2006;291:L862-70 pubmed
Wen H, Hogaboam C, Gauldie J, Kunkel S. Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile. Am J Pathol. 2006;168:1940-50 pubmed
Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, McClanahan T, et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity. 2005;23:479-90 pubmed
Proust B, Nahori M, Ruffie C, Lefort J, Vargaftig B. Persistence of bronchopulmonary hyper-reactivity and eosinophilic lung inflammation after anti-IL-5 or -IL-13 treatment in allergic BALB/c and IL-4Ralpha knockout mice. Clin Exp Allergy. 2003;33:119-31 pubmed

image

image 1 :

Cell Proliferation Induced by IL-13 and Neutralization by Mouse IL-13 Antibody.

product information

brand :

R&D Systems

master code :

MAB413

SKU :

MAB413-100

product name :

IL-13 Antibody

description :

The Mouse IL-13 Antibody from R&D Systems is a rat monoclonal antibody to IL-13. This antibody reacts with mouse. The Mouse IL-13 Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

IL-13

category :

Primary Antibodies

sizes available :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

38213

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse IL-13, Accession # P20109

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Mouse

specificity :

Detects mouse IL-13 in ELISAs and Western blots

gene symbol :

IL13

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

accessionNumbers :

P20109

applications :

Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)

USD :

442 USD

alt names :

ALRHMGC116789, BHR1interleukin-13, IL13, IL-13MGC116788, interleukin 13, MGC116786, NC30, P600

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage